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Akademický článek

Decreased hepatic production of very low density lipoproteins following activation of fatty acid oxidation by Ro 22-0654.

Autor: M Yamamoto, N Fukuda, J Triscari, A C Sullivan, J A Ontko

Publikováno v: Journal of Lipid Research, Vol 26, Iss 10, Pp 1196-1204 (1985)

In fed rat livers perfused with [1-14C]oleic acid, Ro 22-0654 (4-amino-5-ethyl-3-thiophenecarboxylic acid methyl ester hydrochloride), an inhibitor of fatty acid synthesis, activated ketogenesis and decreased the secretion of triglyceride in very low

Externí odkaz: https://doaj.org/article/44afc60e43fa4d1bb178b3d295c5563d

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Pharmacokinetic interaction between propranolol and the HMG-CoA reductase inhibitors pravastatin and lovastatin

Autor: HY Pan, D. Wang‐Iverson, J. Triscari, BN Swanson, DA Willard, SA Smith, AR DeVault

Publikováno v: British Journal of Clinical Pharmacology. 31:665-670

1. Single oral 20 mg doses of the HMG-CoA reductase inhibitors pravastatin and lovastatin, with and without concomitant propranolol (40 mg twice daily), were administered to 16 healthy male subjects participating in a randomized, four-way crossover s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc6d2c299ad3ab7d75291d73cda5406f
https://doi.org/10.1111/j.1365-2125.1991.tb05590.x

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Steady state serum concentrations of pravastatin and digoxin when given in combination

Autor: J. Triscari, DA Willard, BN Swanson, AR DeVault, AI Cohen, HY Pan

Publikováno v: British Journal of Clinical Pharmacology. 36:263-265

Pravastatin is an HMG CoA reductase inhibitor used in the treatment of hypercholesterolaemia. The steady state pharmacokinetics of pravastatin (20 mg) and digoxin (0.2 mg) were evaluated in 18 healthy male subjects following the administration of eac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af8c3330d9457a840d79abe6bfa4c4e
https://doi.org/10.1111/j.1365-2125.1993.tb04227.x

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Matrix study of irbesartan with hydrochlorothiazide in mild-to-moderate hypertension

Autor: Robert M. Guthrie, Richard A. Reeves, Mahendr S. Kochar, J. Triscari, Kenneth Kassler-Taub

Publikováno v: American journal of hypertension. 12(8 Pt 1)

The purpose of this study was to assess the safety and antihypertensive dose-response effects of irbesartan and hydrochlorothiazide (HCTZ) in patients with mild-to-moderate hypertension. After a 4- to 5-week single-blind placebo lead-in period, 683 p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc92786e1f243eb1341ec4efc936048
https://pubmed.ncbi.nlm.nih.gov/10480473

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