Zobrazeno 1 - 10
of 143
pro vyhledávání: '"J Thomas, Cunningham"'
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Background The supraoptic nucleus (SON) of the hypothalamus contains magnocellular neurosecretory cells that secrete the hormones vasopressin and oxytocin. Sex differences in SON gene expression have been relatively unexplored. Our study use
Externí odkaz:
https://doaj.org/article/d27f8dc7eace4a2cada5663dc14fc7e4
Autor:
Ella A. Kasanga, Joel Little, Tamara R. McInnis, Nicoleta Bugnariu, J. Thomas Cunningham, Michael F. Salvatore
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Preservation of motor capabilities is vital to maintaining independent daily living throughout a person's lifespan and may mitigate aging-related parkinsonism, a progressive and prevalent motor impairment. Physically active lifestyles can mitigate ag
Externí odkaz:
https://doaj.org/article/2a4eb8df6edc459f9e6d2985d1a77e0f
Autor:
George E. Farmer, Anna Amune, Martha E. Bachelor, Phong Duong, Joseph P. Yuan, J. Thomas Cunningham
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Neuropeptide release in the brain has traditionally been difficult to observe. Existing methods lack temporal and spatial resolution that is consistent with the function and size of neurons. We use cultured “sniffer cells” to improve the
Externí odkaz:
https://doaj.org/article/5d31e5e9234347df89331ea08aac6961
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 323(5)
Dilutional hyponatremia associated with liver cirrhosis is due to inappropriate release of arginine vasopressin (AVP). Elevated plasma AVP causes water retention resulting in a decrease in plasma osmolality. Cirrhosis, in this study caused by ligatio
Autor:
Shuping Jia, Nataliya Rybalchenko, Kishor Kunwar, George E. Farmer, Joel T. Little, Glenn M. Toney, J. Thomas Cunningham
Publikováno v:
Journal of Neurophysiology. 128:1383-1394
Chronic intermittent hypoxia (CIH), an animal model of sleep apnea, has been shown to alter the activity of second-order chemoreceptor neurons in the caudal nucleus of the solitary tract (cNTS). Although numerous studies have focused on excitatory pl
Autor:
Michael F, Salvatore, Isabel, Soto, Ella A, Kasanga, Rachael, James, Marla K, Shifflet, Kirby, Doshier, Joel T, Little, Joshia, John, Helene M, Alphonso, J Thomas, Cunningham, Vicki A, Nejtek
Publikováno v:
Journal of Parkinson's Disease. 12:1897-1915
Background: Rodent Parkinson’s disease (PD) models are valuable to interrogate neurobiological mechanisms of exercise that mitigate motor impairment. Translating these mechanisms to human PD must account for physical capabilities of the patient. Ob
Publikováno v:
Physiological Reports, Vol 5, Iss 10, Pp n/a-n/a (2017)
Abstract Obstructive sleep apnea is associated with hypertension and cardiovascular disease. Chronic intermittent hypoxia is used to model the arterial hypoxemia seen in sleep apnea patients and is associated with increased sympathetic nerve activity
Externí odkaz:
https://doaj.org/article/d63728233cdc466b814e25534e52c930
Publikováno v:
GeroScience
Vascular cognitive impairment (VCI) is a term that encompasses a continuum of cognitive disorders with cerebrovascular pathology contribution, ranging from mild cognitive impairment to vascular dementia (VaD). VCI and VaD, thus, represent an interest
Publikováno v:
Journal of Neurophysiology. 124:591-609
Designer receptors exclusively activated by designer drugs (DREADDs) modify cellular activity following administration of the exogenous ligand clozapine-N-oxide (CNO). However, some reports indicate CNO may have off-target effects. The current studie
Autor:
Kirthikaa Balapattabi, Rebecca L. Cunningham, Martha Bachelor, J. Thomas Cunningham, Joel T. Little
Publikováno v:
Neuroendocrinology
Introduction: Hyponatremia due to elevated arginine vasopressin (AVP) secretion increases mortality in liver failure patients. No previous studies have addressed sex differences in hyponatremia in liver failure animal models. Objective: This study ad