Zobrazeno 1 - 9
of 9
pro vyhledávání: '"J Tabitha, Hees"'
Publikováno v:
Cells, Vol 10, Iss 12, p 3436 (2021)
Established disease models have helped unravel the mechanistic underpinnings of pathological phenotypes in Parkinson’s disease (PD), the second most common neurodegenerative disorder. However, these discoveries have been limited to relatively simpl
Externí odkaz:
https://doaj.org/article/ae819050b53c443b91d8cfebcf70bee6
Autor:
J. Tabitha Hees, Angelika B. Harbauer
Mitochondrial quality control failure is frequently observed in neurodegenerative diseases. The detection of damaged mitochondria by stabilization of PTEN-induced kinase 1 (PINK1) requires transport ofPink1mRNA by tethering it to the mitochondrial su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::370cf0abdd87d28c6ec47f0a85146fa0
https://doi.org/10.1101/2023.02.06.527276
https://doi.org/10.1101/2023.02.06.527276
Autor:
J Tabitha, Hees, Angelika B, Harbauer
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2431
The use of fluorescent proteins has revolutionized the study of protein localization and transport. However, the visualization of other molecules and specifically RNA during live-cell imaging remains challenging. In this chapter, we provide guidance
Autor:
J. Tabitha Hees, Angelika B. Harbauer
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619896
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39806aff6bfff45914475e50ca58c1c6
https://doi.org/10.1007/978-1-0716-1990-2_11
https://doi.org/10.1007/978-1-0716-1990-2_11
Autor:
Angelika B. Harbauer, J. Tabitha Hees, Simone Wanderoy, Inmaculada Segura, Whitney Gibbs, Yiming Cheng, Martha Ordonez, Zerong Cai, Romain Cartoni, Ghazaleh Ashrafi, Chen Wang, Fabiana Perocchi, Zhigang He, Thomas L. Schwarz
Publikováno v:
Neuron 110, 1516-1531.e9 (2022)
PTEN-induced kinase 1 (PINK1) is a short-lived protein required for the removal of damaged mitochondria through Parkin translocation and mitophagy. Because the short half-life of PINK1 limits its ability to be trafficked into neurites, local translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa706e9325823230f048bfb2512a6aa
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64542
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64542
Autor:
Tammy Szu-Yu Ho, J. Tabitha Hees, Zhuqiu Xu, Riki Kawaguchi, Natalia P. Biscola, Daniel G Taub, Kuchuan Chen, Xirui Chen, Lee B. Barrett, Long Cheng, Christopher V. Gabel, Leif A. Havton, Daniel H. Geschwind, Clifford J. Woolf
SummaryCNS neurons do not regenerate after injury, leading to permanent functional deficits. Although sensory and motor neuron axons do regrow after peripheral nerve injury, functional outcome is limited due to the incomplete and slow regrowth. The l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e159f8008a764a2e520e980818808483
https://doi.org/10.1101/2021.11.02.466937
https://doi.org/10.1101/2021.11.02.466937
Publikováno v:
Biological Chemistry
Mitochondria are key players of cellular metabolism, Ca2+ homeostasis, and apoptosis. The functionality of mitochondria is tightly regulated, and dysfunctional mitochondria are removed via mitophagy, a specialized form of autophagy that is compromise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d447c5db4025e6e57a8220a632dc6b
https://hdl.handle.net/21.11116/0000-0007-AAC1-F21.11116/0000-0007-AAC3-D
https://hdl.handle.net/21.11116/0000-0007-AAC1-F21.11116/0000-0007-AAC3-D
Autor:
Angelika B. Harbauer, J. Tabitha Hees
Publikováno v:
American Journal of Biomedical Science & Research
Mitochondria are not only the “power houses of the cell” but also function as a major Ca2+ buffer in the cell. Mitochondrial dynamics respond to the level of Ca2+ in the cell in order to maintain a beneficial feedback cycle between Ca2+ buffering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a454cbe451646619c6c1d5f81a77722
https://hdl.handle.net/21.11116/0000-0006-7CD7-D21.11116/0000-0006-7CD9-B
https://hdl.handle.net/21.11116/0000-0006-7CD7-D21.11116/0000-0006-7CD9-B
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