Zobrazeno 1 - 10
of 37
pro vyhledávání: '"J T Pento"'
Publikováno v:
American Journal of Pharmacology and Toxicology. 1:60-64
We reported previously that L-methioninase targeted to the urokinase receptor of MCF-7 breast cancer cells is significantly more effective in inhibiting cell proliferation and migration than free L-methioninase both in vitro and in vivo. L-methionina
Publikováno v:
Cancer Investigation. 17:10-18
Metastatic spread of breast cancer is responsible for most of the morbidity and mortality associated with this disease. Thus, it is important to identify agents with antimetastatic activity. Because invasiveness and tumor cell attachment are fundamen
Publikováno v:
Anti-Cancer Drugs. 8:964-973
Analog II (1,1-dichloro-cis-2,3-diarylcyclopropane), previously shown to be a pure antiestrogen in mice, was examined for potential antitumor activity on human breast cancer cells in culture. In this study, Analog II produced a dose-related antiproli
Publikováno v:
Anti-Cancer Drugs. 5:429-436
Compound 4d ((E)- and (Z)-1,1-Dichloro-2-[4-(benzyloxy)-phenyl]2,3-bis(4-methoxyphenyl) cyclopropane) and compound 5c ((Z)-1,1-Dichloro-2-[4-(benzyloxy)-phenyl]- 2-(4-methoxyphenyl)-3-phenylcyclopropane) are two members of a novel series of triarylcy
Publikováno v:
ChemInform. 22
A series of 1,1-dichloro-2,2,3-triarylcyclopropanes (DTACs) was synthesized and evaluated as pure antiestrogens. Addition of 4-methoxy- or 4-(benzyloxy)phenyl Grignard reagents to p-methoxy, p-benzyloxy, or unsubstituted deoxybenzoins, followed by de
Publikováno v:
Anti-Cancer Drugs. 2:487-494
The potential antitumor activity of a series of novel cyclopropyl compounds, which lack estrogen agonist activity, was evaluated in estrogen receptor positive human breast cancer cells (MCF-7) in culture. The compounds were evaluated to determine the
Publikováno v:
Journal of Medicinal Chemistry. 34:842-851
A series of 1,1-dichloro-2,2,3-triarylcyclopropanes (DTACs) was synthesized and evaluated as pure antiestrogens. Addition of 4-methoxy- or 4-(benzyloxy)phenyl Grignard reagents to p-methoxy, p-benzyloxy, or unsubstituted deoxybenzoins, followed by de
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 37(9)
Autor:
X P, Zang, J T, Pento
Publikováno v:
Clinicalexperimental metastasis. 18(7)
Endogenous growth factors and cytokines are known to have a major influence on the progression, motility and invasiveness of tumor cells. We have reported previously that conditioned media from mouse fibroblasts increases the motility of breast cance
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 36(8)