Zobrazeno 1 - 10
of 127
pro vyhledávání: '"J T August"'
Autor:
Hadia Syahirah Abd Raman, Muhammad Farhan Sjaugi, Li Chuin Chong, Asif M. Khan, Swan Tan, J. T. August, Siew Chinn Fong, Nik Elena Nik Mohamed
Publikováno v:
Viruses
Volume 13
Issue 5
Viruses, Vol 13, Iss 871, p 871 (2021)
Volume 13
Issue 5
Viruses, Vol 13, Iss 871, p 871 (2021)
Avian influenza virus A (H7N9), after circulating in avian hosts for decades, was identified as a human pathogen in 2013. Herein, amino acid substitutions possibly essential for human adaptation were identified by comparing the 4706 aligned overlappi
Publikováno v:
PeerJ
PeerJ, Vol 7, p e7954 (2020)
PeerJ, Vol 7, p e7954 (2020)
BackgroundInfluenza A (H5N1) virus is a global concern with potential as a pandemic threat. High sequence variability of influenza A viruses is a major challenge for effective vaccine design. A continuing goal towards this is a greater understanding
Autor:
Zhijia Liu, Chaojun Song, Yuanjie Sun, Fei Liu, Haitao Li, Kui Zhang, Kun Yang, Yuying Wei, Jiuyu Gong, J. T. August, Yongming Li, Boquan Jin
Publikováno v:
The Journal of Gene Medicine. 14:353-362
Background A number of strategies have been used to improve the efficacy of the DNA vaccine for the treatment of tumors. These strategies, ranging from activating CD4+ T cell, manipulating antigen presentation and/or processing to anti-angiogenesis,
Autor:
Jiang Xu, K Sun, K Yang, Ernesto T. A. Marques, J. T. August, Kellathur N. Srinivasan, Jerome Salmon
Publikováno v:
Gene Therapy
In our previous study by Gupta et al, dominant T-cell epitopes of SARS CoV-N(N) protein were predicted by software. The spectrum of interferon (IFN)-gamma responses of Balb/c mice immunized against two different forms of SARS CoV-N plasmid was then a
Autor:
Ricardo Galler, Milton Maciel, Marli Tenório Cordeiro, J. T. August, Rita de Cássia Carvalho Maia, Klécia Marília Soares de Melo Cassemiro, Regina Celia Bressan Queiroz de Figueiredo, Marcos da Silva Freire, Rafael Dhalia, Marcia Archer da Motta, Fábia da Silva Pereira Cruz, Ernesto T. A. Marques
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 4, p e0003693 (2015)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Attenuated yellow fever (YF) virus 17D/17DD vaccines are the only available protection from YF infection, which remains a significant source of morbidity and mortality in the tropical areas of the world. The attenuated YF virus vaccine, which is used
Autor:
E Schweibert, Hai-Quan Mao, S. M. Walsh, V. L. Truong-Le, William B. Guggino, J. T. August, Kam W. Leong
Publikováno v:
Archives of Biochemistry and Biophysics. 361:47-56
A DNA and gelatin nanoparticle coacervate containing chloroquine and calcium, and with the cell ligand transferrin covalently bound to the gelatin, has been developed as a gene delivery vehicle. In this study, the coacervation conditions which result
Autor:
Henrik Sengeløv, A. M. Cieutat, Dorothy F. Bainton, Niels Borregaard, Peter Lobel, J. T. August, Lars Kjeldsen
Publikováno v:
Scopus-Elsevier
During granulocyte differentiation in the bone marrow (BM), neutrophilic leukocyte precursors synthesize large amounts of lysosomal enzymes. These enzymes are sequestered into azurophilic storage granules until used days later for digestion of phagoc
Autor:
Drew M. Pardoll, Tzyy Choou Wu, Kathleen R. Cho, J. T. August, Raphael P. Viscidi, Kevin Staveley-O'Carroll, Hyam I. Levitsky, Frank G. Guarnieri, Lora Hedrick
Publikováno v:
Proceedings of the National Academy of Sciences. 92:11671-11675
The presentation of antigenic peptides by major histocompatibility complex (MHC) class II molecules to CD4+ T cells is critical to the function of the immune system. In this study, we have utilized the sorting signal of the lysosomal-associated membr
Autor:
J F Rowell, A L Ruff, F G Guarnieri, K Staveley-O'Carroll, X Lin, J Tang, J T August, R F Siliciano
Publikováno v:
The Journal of Immunology. 155:1818-1828
A subset of endogenously synthesized Ags can be processed for class II-restricted presentation, probably through multiple mechanisms. Processing of exogenous Ags for class II-restricted presentation appears to occur in unique endosomal processing com