Zobrazeno 1 - 9 of 9 pro vyhledávání: '"J T, Sahlroot"'
1
A LIMITED SAMPLING METHOD FOR THE ESTIMATION OF FLUNARIZINE AREA UNDER THE CURVE (AUC) AND MAXIMUM PLASMA CONCENTRATION (CMAX)
Autor: Iftekhar Mahmood, J T Sahlroot
Publikováno v: Biopharmaceutics & Drug Disposition. 18:117-126
A limited sampling model has been developed for flunarizine following a 30 mg oral dose in epileptic patients who were receiving phenytoin or carbamazepine or both, to estimate the area under the curve (AUC) and maximum plasma concentration (Cmax). T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c9fc6a4c3a8e4bf7e1d04519e3ee81a
https://doi.org/10.1002/(sici)1099-081x(199703)18:2<117::aid-bdd5>3.0.co
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2
Analysis of Results: Statistical Principles
Autor: D. Hoberman, J. T. Sahlroot
Publikováno v: Clinical Trials in Neurology ISBN: 9781849968560
Human beings are anything but homogeneous experimental units. No matter how rigorous the effort to restrict a pool of patient candidates for a controlled clinical trial, even an effective treatment accounts for only a small portion of the resulting r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::565c164902829403451c7d4aee156710
https://doi.org/10.1007/978-1-4471-3787-0_10
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4
A limited sampling method for the estimation of flunarizine area under the curve (AUC) and maximum plasma concentration (Cmax)
Autor: I, Mahmood, J T, Sahlroot
Publikováno v: Biopharmaceuticsdrug disposition. 18(2)
A limited sampling model has been developed for flunarizine following a 30 mg oral dose in epileptic patients who were receiving phenytoin or carbamazepine or both, to estimate the area under the curve (AUC) and maximum plasma concentration (Cmax). T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ddf4401ec1d5fb2c690868c545ad1c4
https://pubmed.ncbi.nlm.nih.gov/9099448
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5
Dezinamide for partial seizures: results of an n-of-1 design trial
Autor: C. B. McCutchen, Michael Privitera, David M. Treiman, Gordon W. Pledger, Adrian Handforth, J. T. Sahlroot, J. H. Wood, James J. Cereghino, M. S. Linde
Publikováno v: Neurology. 44(8)
Background: Dezinamide (DZM, ADD 94057) is a potential antiepileptic drug that binds to the voltage-sensitive sodium channel and showed preliminary evidence of efficacy and safety in an open-label study.Methods: Our double-blind, placebo-controlled t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52cb19c7a0c175e9e0865dd1a2c40b7
https://pubmed.ncbi.nlm.nih.gov/8058148
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7
Felbamate for partial seizures: Results of a controlled clinical trial
Autor: J. Y. Tsay, Nina M. Graves, Philip H. Sheridan, Fritz E. Dreifuss, T. L. Sierzant, G. Cooper, Margaret Jacobs, I. Drury, Gordon W. Pledger, Soo Ik Lee, E. Bertram, James J. Cereghino, Ilo E. Leppik, Nancy Santilli, M. Ashworth, J. T. Sahlroot
Publikováno v: Neurology. 41:1785-1785
Felbamate (2-phenyl-1,3-propanediol dicarbamate) has a favorable preclinical profile in animal models of epilepsy. We present the results of a double-blind, randomized, placebo-controlled clinical trial in patients with partial seizures. Criteria for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8664b59742028ae96ac2cacf60028efc
https://doi.org/10.1212/wnl.41.11.1785
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