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Cebranopadol: novel dual opioid/NOP receptor agonist analgesic

Autor: F. Lin, B. Lu, J. T. Nguyen, H. E. Kinecki, T. N. Watkins, Robert B. Raffa, V. Phan, G. Burdge, J. Gambrah, M. A. Sesay, A. Ruan

Publikováno v: Journal of Clinical Pharmacy and Therapeutics. 42:8-17

SummaryWhat is known and objective Chronic pain presents a difficult clinical challenge because of the limited efficacy, the limiting adverse-effect profile or the abuse potential of current analgesic options. Cebranopadol is a novel new agent in cli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8842f1f4ddafa209aac7d97c08636ff5
https://doi.org/10.1111/jcpt.12461

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CD7 delivers a pro-apoptotic signal during galectin-1-induced T cell death

Autor: K E, Pace, H P, Hahn, M, Pang, J T, Nguyen, L G, Baum

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 165(5)

Galectin-1, an endogenous lectin expressed in lymphoid organs and immune-privileged sites, induces death of human and murine thymocytes and T cells. Galectin-1 binds to several glycoproteins on the T cell surface, including CD7. However, the T cell s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b06d4d2a858fa8ba2e1e7aefa5739f49
https://pubmed.ncbi.nlm.nih.gov/10946254

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Adeno-associated virus and other potential vectors for angiostatin and endostatin gene therapy

Autor: J T, Nguyen

Publikováno v: Advances in experimental medicine and biology. 465

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e254a5a4707777bdcf3b49a0d3ccd2c8
https://pubmed.ncbi.nlm.nih.gov/10810649

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Vascular endothelial growth factor as a target for cancer gene therapy

Autor: J T, Nguyen

Publikováno v: Advances in experimental medicine and biology. 465

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90cdc9e3f0291cf0c8c5511344ec041a
https://pubmed.ncbi.nlm.nih.gov/10810648

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Galectin-1 specifically modulates TCR signals to enhance TCR apoptosis but inhibit IL-2 production and proliferation

Autor: G N, Vespa, L A, Lewis, K R, Kozak, M, Moran, J T, Nguyen, L G, Baum, M C, Miceli

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(2)

Galectin-1 is an endogenous lectin expressed by thymic and lymph node stromal cells at sites of Ag presentation and T cell death during normal development. It is known to have immunomodulatory activity in vivo and can induce apoptosis in thymocytes a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7b186ea0c218a7e67a65da2e3040202
https://pubmed.ncbi.nlm.nih.gov/9916701

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Adeno-associated virus-mediated delivery of antiangiogenic factors as an antitumor strategy

Autor: J T, Nguyen, P, Wu, M E, Clouse, L, Hlatky, E F, Terwilliger

Publikováno v: Cancer research. 58(24)

Antiangiogenic tumor therapies have recently attracted intense interest for their broad-spectrum action, low toxicity, and, in the case of direct endothelial targeting, an absence of drug resistance. To promote tumor regression and to maintain dorman

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::38cf97dcc7c3161263c85e8a6ace921a
https://pubmed.ncbi.nlm.nih.gov/9865720

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Invasive melanoma patients treated with Canvaxin specific active immunotherapy show serconversion for both IgG and IgM antibody responses to numerous protein and glycolipid tumor antigens

Autor: Richard Essner, S. Kuhns, J. T. Nguyen, D. van Epps, D. Buckman, L. Zhang, Mark B. Faries, J. Thomas, Eddy C. Hsueh, C. R. Ill, Leland J. Foshag

Publikováno v: Journal of Clinical Oncology. 23:2574-2574

2574 Background: Although few nonsurgical treatment options offer significant benefit for patients with high-risk melanoma, extensive matched-pair control studies of phase II trials indicate that C...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4066b77ed70effe8b50e2e20ef3e1862
https://doi.org/10.1200/jco.2005.23.16_suppl.2574

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Akademický článek

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pH-dependent structural transitions of Alzheimer amyloid peptides

Autor: Daniel A. Kirschner, Witold K. Surewicz, J. T. Nguyen, Paul E. Fraser

Publikováno v: Scopus-Elsevier

To understand the molecular interactions leading to the assembly of beta/44 protein into the hallmark fibrils of Alzheimer's disease (AD), we have examined the ability of synthetic peptides that correspond to the beta/A4 extracellular sequence to for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d82512da7cbfccc9f3660d1456389a
http://www.scopus.com/inward/record.url?eid=2-s2.0-0025838381&partnerID=MN8TOARS

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