Zobrazeno 1 - 10
of 112
pro vyhledávání: '"J T, Bigger"'
Autor:
George Hripcsak, F. Liu, Yiye Zhang, Chunhua Weng, Junfeng Gao, J. T. Bigger, Yu Li, Patrick B. Ryan
SummaryObjective: To improve the transparency of clinical trial generalizability and to illustrate the method using Type 2 diabetes as an example.Methods: Our data included 1,761 diabetes clinical trials and the electronic health records (EHR) of 26,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989de694509db42fc42064fdb850c023
https://europepmc.org/articles/PMC4081748/
https://europepmc.org/articles/PMC4081748/
Autor:
J. T. Bigger, Andrew E. Epstein, Ronald W.F. Campbell, Craig M. Pratt, Lukas Kappenberger, Stuart J. Pocock, G. Breithardt, Sanjeev Saksena, Karl H. Kuck, A. J. Camm, Albert L. Waldo
Publikováno v:
Journal of Cardiovascular Electrophysiology. 10:1534-1549
Antiarrhythmic Drug Efficacy in Patients with an ICD. There are a number of novel ways in which implantable cardioverter defibrillator (ICD) endpoints can he used in clinical trials to evaluate antiarrhythmic drugs. The advances in ICD technology (st
Publikováno v:
Statistics in Medicine. 18:1943-1959
The Multicenter Automatic Defibrillator Implantation Trial (MADIT) showed a conclusive 54 per cent reduction in mortality in patients with inducible sustained monomorphic ventricular tachycardia (VT) and impaired left ventricular function who receive
Publikováno v:
Medicine & Science in Sports & Exercise. 29:812-817
The association between increasing age and decreasing vagal modulation is well known. However, the importance of fitness as a determinant of the decline in vagal modulation with age is not established. To test the hypothesis that decreasing vagal mod
Autor:
J. T. Bigger, L M Rolnitzky, Paul Albrecht, Richard C. Steinman, J L Fleiss, Richard J. Cohen
Publikováno v:
Circulation. 93:2142-2151
Background The purposes of the present study were (1) to establish normal values for the regression of log(power) on log(frequency) for RR-interval fluctuations in healthy middle-aged persons, (2) to determine the effects of myocardial infarction on
Autor:
R Lazzara, David E. Mann, M. J. Reiter, F. I. Marcus, James A. Reiffel, J W Mason, J. T. Bigger
Publikováno v:
Progress in Cardiovascular Diseases. 38:347-358
The Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) trial was completed in 1992 and the primary results were reported in 1993. Since then, considerable discussion about this trial has taken place and new trial results have bee
Publikováno v:
Computers and Biomedical Research. 28:221-238
We have developed a computer-assisted method that creates digital maps of the viable and infarcted regions of tetrazolium-stained gross cardiac sections. Here we describe and test the method, using a canine occlusion-reperfusion infarction model. Qua
Autor:
J. T. Bigger, Linda M. Rolnitzky, Schneider Wj, Joseph L. Fleiss, Richard C. Steinman, Phyllis K. Stein
Publikováno v:
Circulation. 91:1936-1943
Background The purpose of this investigation was to establish normal values of RR variability for middle-aged persons and compare them with values found in patients early and late after myocardial infarction. We hypothesized that presence or absence
Autor:
Emilia Bagiella, Peter A. Shapiro, Richard P. Sloan, Jack M. Gorman, J. T. Bigger, Michael M. Myers, Richard C. Steinman
Publikováno v:
Biological Psychology. 38:133-142
Heart period variability (HPV) measured from 24 h ECG recordings predicts mortality following myocardial infarction and may be a measure of cardiovascular health in the general population. Since epidemiologic evaluation of healthy people will require
Autor:
Myunghee Cho Paik, Peter A. Shapiro, Richard P. Sloan, Richard C. Steinman, Emilia Bagiella, S.M. Boni, J. T. Bigger, Jack M. Gorman
Publikováno v:
Biological Psychology. 37:89-99
Although many laboratory studies have demonstrated changes in cardiac autonomic control during psychological stress, few have attempted to demonstrate this effect in ambulatory subjects. To address this issue, 24-h electrocardiographic recordings of