Perturbations of Glutathione and Sphingosine Metabolites in Port Wine Birthmark Patient-Derived Induced Pluripotent Stem Cells

Autor: Vi Nguyen, Jacob Kravitz, Chao Gao, Marcelo L. Hochman, Dehao Meng, Dongbao Chen, Yunguan Wang, Anil G. Jegga, J Stuart Nelson, Wenbin Tan

Publikováno v: Metabolites, Vol 13, Iss 9, p 983 (2023)

Port Wine Birthmarks (PWBs) are a congenital vascular malformation on the skin, occurring in 1–3 per 1000 live births. We have recently generated PWB-derived induced pluripotent stem cells (iPSCs) as clinically relevant disease models. The metaboli

Externí odkaz: https://doaj.org/article/fb97ec88e52e441c8999d13348cecb6c

The Pathogenesis of Port Wine Stain and Sturge Weber Syndrome: Complex Interactions between Genetic Alterations and Aberrant MAPK and PI3K Activation

Autor: Vi Nguyen, Marcelo Hochman, Martin C. Mihm, J. Stuart Nelson, Wenbin Tan

Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 9, p 2243 (2019)

Port wine stain (PWS) is a congenital vascular malformation involving human skin. Approximately 15−20% of children a facial PWS involving the ophthalmic (V1) trigeminal dermatome are at risk for Sturge Weber syndrome (SWS), a neurocutaneous disorde

Externí odkaz: https://doaj.org/article/f824e1e5723f48b19dc10fc9adaf490a

Characterization of Laser‐Resistant Port Wine Stain Blood Vessels UsingIn VivoReflectance Confocal Microscopy

Autor: Wenbin Tan, J. Stuart Nelson, Zhen Tang, Jian Huang, Jianyun Lu, Yaping Xiang, Jing Chen, Zhibing Fu, Jinhua Huang

Publikováno v: Lasers in Surgery and Medicine. 51:841-849

Author(s): Fu, Zhibing; Huang, Jinhua; Xiang, Yaping; Huang, Jian; Tang, Zhen; Chen, Jing; Nelson, J Stuart; Tan, Wenbin; Lu, Jianyun | Abstract: Background and objectivesPort wine stain (PWS) is a congenital vascular malformation of the human skin.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5634d254aa83111779475540f9767139
https://doi.org/10.1002/lsm.23134

Clinical presentation and outcomes after endovascular management in a mixed pediatric and adult Klippel-Trenaunay syndrome population

Autor: A. Lam, Laura K. Findeiss, Rebecca Bennett, H. Javan, Nadine Abi-Jaoudeh, Kristen M. Kelly, J. Stuart Nelson, K. Nelson

Publikováno v: Journal of vascular surgery. Venous and lymphatic disorders, vol 9, iss 6

Objective We retrospectively studied the clinical presentations and outcomes of endovascular management in a mixed pediatric and adult Klippel-Trenaunay syndrome (KTS) population at a single academic medical center. Methods We performed a retrospecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c145deb3fb266c1eef20701d508f47e
https://pubmed.ncbi.nlm.nih.gov/33753300

Propranolol as a potentially novel treatment of arteriovenous malformations

Autor: Jian Huang, Jinwei Wang, Jianyun Lu, Jinhua Huang, Zhaoqi Yin, Radean T. Anvari, Yaping Xiang, Jing Chen, Shiyao Pei, Wenbin Tan, J. Stuart Nelson

Publikováno v: JAAD case reports, vol 4, iss 4
JAAD Case Reports, Vol 4, Iss 4, Pp 355-358 (2018)
JAAD Case Reports
Lu, J; Anvari, R; Wang, J; Huang, J; Pei, S; Xiang, Y; et al.(2018). Propranolol as a potentially novel treatment of arteriovenous malformations.. JAAD case reports, 4(4), 355-358. doi: 10.1016/j.jdcr.2017.11.005. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7343x3mk

Author(s): Lu, Jianyun; Anvari, Radean; Wang, Jinwei; Huang, Jian; Pei, Shiyao; Xiang, Yaping; Huang, Jinhua; Yin, Zhaoqi; Chen, Jing; Nelson, J Stuart; Tan, Wenbin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128d59e88dd5adb53201ee63775a20ff
https://doi.org/10.1016/j.jdcr.2017.11.005