Zobrazeno 1 - 10
of 1 158
pro vyhledávání: '"J Steer"'
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 7, Pp 100576- (2024)
Hypercholesterolemia is frequently intertwined with hepatosteatosis, hypertriglyceridemia, and hyperglycemia. This study is designed to assess the therapeutic efficacy of miR-206 in contrast to statins in the context of managing hypercholesterolemia
Externí odkaz:
https://doaj.org/article/c0d29ea5d23745b7893ea8750dfe7194
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Background Inhibitors of ornithine decarboxylase (ODC) are effective at preventing colorectal cancer (CRC). However, their high toxicity limits their clinical application. This study was aimed to explore the potential of microRNAs (miRNAs) a
Externí odkaz:
https://doaj.org/article/5c8b265355894efcaa3789fd9d0296d0
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1652-1663 (2022)
Abstract Hepatitis B virus (HBV) infection is a major risk factor of liver cirrhosis and hepatocellular carcinoma. Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated protein 9 (Cas9) has been used to precisely edit
Externí odkaz:
https://doaj.org/article/4ce12ca9a5f640229d2abe73863aa52a
Autor:
Emma J. Steer, Zhaokang Yang, Moza M. Al-Owais, Hannah M. Kirton, Edward White, Derek S. Steele
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background and purpose: While flecainide is now an accepted treatment for arrhythmias associated with catecholaminergic polymorphic ventricular tachycardia (CPVT), its mechanism of action remains controversial. In studies on myocytes from CPVT mice,
Externí odkaz:
https://doaj.org/article/67857d3bbcf941a2ace61eb090bed825
Autor:
Anala Shetty, Seunghyun Lim, Phoebe Strell, Clifford J. Steer, Juan Carlos Rivera-Mulia, Walter C. Low
Publikováno v:
Cell Transplantation, Vol 32 (2023)
Currently, there is a significant shortage of transplantable organs for patients in need. Interspecies chimerism and blastocyst complementation are alternatives for generating transplantable human organs in host animals such as pigs to meet this shor
Externí odkaz:
https://doaj.org/article/a9d00e310df4438ca1fd14e1bc787dc9
Publikováno v:
Cell Transplantation, Vol 31 (2022)
A growing need for organs and novel cell-based therapies has provided a niche for approaches like interspecies chimeras. To generate organs from one donor species in another host species requires techniques such as blastocyst complementation and gene
Externí odkaz:
https://doaj.org/article/c7c51135bf104ecd9a685251472419db
Autor:
M. Ruiz-Estevez, A. T. Crane, P. Rodriguez-Villamil, F. L. Ongaratto, Yun You, A. R. Steevens, C. Hill, T. Goldsmith, D. A. Webster, L. Sherry, S. Lim, N. Denman, W. C. Low, D. F. Carlson, J. R. Dutton, C. J. Steer, O. Gafni
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background There are over 17,000 patients in the US waiting to receive liver transplants, and these numbers are increasing dramatically. Significant effort is being made to obtain functional hepatocytes and liver tissue that can for therapeu
Externí odkaz:
https://doaj.org/article/4d8b1183f68246fe85476a7b0d4f9213
Autor:
Philip J. Steer
Publikováno v:
International Journal of Cardiology Congenital Heart Disease, Vol 4, Iss , Pp 100168- (2021)
Women with congenital heart disease should be encouraged to breastfeed their babies unless there are major contraindications.
Externí odkaz:
https://doaj.org/article/44b6f71651674f829c8088f83e55a4a1
Autor:
Sidsel Boie, Julie Glavind, Niels Uldbjerg, Jannet J. H. Bakker, Joris A. M. van der Post, Philip J. Steer, Pinar Bor
Publikováno v:
BMC Pregnancy and Childbirth, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Oxytocin is an effective drug for induction of labour, but is associated with serious adverse effects of which uterine tachysystole, fetal distress and the need of immediate delivery are the most common. Discontinuation of oxytoci
Externí odkaz:
https://doaj.org/article/c45449e50fe648b3b3069cbaed0b946e
Autor:
Philip J. Steer, Sabine Ernst
Publikováno v:
International Journal of Cardiology Congenital Heart Disease, Vol 2, Iss , Pp 100083- (2021)
Peer review has a key role in ensuring that information published in scientific journals is as truthful, valid and accurate as possible. It relies on the willingness of researchers to give of their valuable time to assess submitted papers, not just t
Externí odkaz:
https://doaj.org/article/5341903e2a8545cbb4f45b3384f61369