Zobrazeno 1 - 10
of 29
pro vyhledávání: '"J Slon-Campos"'
Autor:
Christina Dold, Mariolina Salio, John Frater, Peter Simmonds, Christopher P. Conlon, J Slon-Campos, Z Yin, David I. Stuart, N F Schwabe, Guido C. Paesen, D Dong, Richard J. Cornall, Paul Thomson, T Lockett, Oliver W. Bayfield, U S Rajapaksa, J W Fry, P Supasa, Jonathan M. Grimes, R Levin, Wanwisa Dejnirattisai, Graham S. Ogg, Dannielle Wellington, Openshaw Pjm., Chen Y-L., Hawkins Dedp., P Zhang, Giorgio Napolitani, Tao Dong, J K Baillie, C Liu, Cesar Lopez-Camacho, Paul Sopp, M A Ansari, Alfred A. Antson, Ker D-S., Persephone Borrow, Susanna Dunachie, Andrew J. McMichael, Juthathip Mongkolsapaya, Yanchun Peng, B Wang, T Rostron, Shona C Moore, Lance Turtle, G Liu, T I de Silva, Krishanthi Subramaniam, Jeremy Ratcliff, Ho L-P., Benedikt M. Kessler, G Kerr, Yuguang Zhao, X Yao, Malcolm G Semple, Gavin R. Screaton, Paul Klenerman, Wayne Paes, R Jing, Alexander J. Mentzer, Y Zhang, Philip J. R. Goulder, Eleanor Barnes, Julian C. Knight
Publikováno v:
Nature Immunology
NATURE IMMUNOLOGY
Nat Immunol
NATURE IMMUNOLOGY
Nat Immunol
The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines and therapeutics will depend on understanding viral immunity. We studied T cell memory in 42 patients following recovery from COVID-19 (28 with mild disease and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f78680cf7c854968fa13a2ef61dd0a2
https://ora.ox.ac.uk/objects/uuid:e5e926ec-b256-4608-9956-84db12d56741
https://ora.ox.ac.uk/objects/uuid:e5e926ec-b256-4608-9956-84db12d56741
Publikováno v:
Journal of General Virology. 101:73-78
Dengue virus (DENV) remains a significant healthcare and socioeconomic burden for endemic countries. Attempts to produce a safe and effective vaccine have been unsuccessful so far, making this task one of the top priorities in the field. We have prev
Autor:
Beibei Wang, D. Zhou, Elizabeth E. Fry, Julian C. Knight, Amy Flaxman, Valdinete Alves do Nascimento, Alexander J. Mentzer, E Barnes, Alex Pauvolid-Corrêa, Sarah C. Gilbert, M Bittaye, Mark A. Williams, Hulswit Rjg., Gavin R. Screaton, Sandra Belij-Rammerstorfer, Chang Liu, Andrew J. Pollard, David R. Hall, Tao Dong, David I. Stuart, Christina Dold, Felipe Gomes Naveca, Wanwisa Dejnirattisai, Elizabeth A. Clutterbuck, Paul Klenerman, Neil G. Paterson, Helen M. Ginn, C Fernandes da Costa, R Levin, Jingshan Ren, Duyvesteyn Hme., Thomas S. Walter, Aekkachai Tuekprakhon, Miles W. Carroll, Donal T. Skelly, R Nutalai, Yuguang Zhao, Thomas A. Bowden, D W Crook, S A Costa Clemens, Marilda M. Siqueira, P Supasa, Susanna Dunachie, S Bibi, Teresa Lambe, Paola Cristina Resende, Cesar Lopez-Camacho, J Slon-Campos, Juthathip Mongkolsapaya, Fabrícia F. Nascimento
Publikováno v:
Cell
Terminating the SARS-CoV-2 pandemic relies upon pan-global vaccination. Current vaccines elicit neutralizing antibody responses to the virus spike derived from early isolates. However, new strains have emerged with multiple mutations: P.1 from Brazil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ac3bb39f884cef9702bb4016069aa5
https://doi.org/10.1016/j.cell.2021.03.055
https://doi.org/10.1016/j.cell.2021.03.055
Autor:
Christina Dold, Miles W. Carroll, C Mason, David Hall, Eleanor Barnes, Cesar Lopez-Camacho, F. Gomes Naveca, Jingshan Ren, M C Nunes, D. Zhou, David I. Stuart, P Goulder, Elizabeth E. Fry, Neil G. Paterson, Shabir A. Madhi, Juthathip Mongkolsapaya, Amy Flaxman, S A Johnson, Teresa Lambe, Valdinete Alves do Nascimento, Sandra Belij-Rammerstorfer, Alexander J. Mentzer, Helen M. Ginn, Tao Dong, Thomas S. Walter, Donal T. Skelly, Paul Klenerman, Z Ditse, Marilda M. Siqueira, Sarah C. Gilbert, Susanna Dunachie, James C. Knight, Alex Pauvolid-Corrêa, P Supasa, Mark A. Williams, Vicky L. Baillie, N Serafin, C Fernandes da Costa, Yuguang Zhao, Andrew J. Pollard, R Nutalai, S Bibi, T G Ritter, Fabrícia F. Nascimento, M Bittaye, Wanwisa Dejnirattisai, Beibei Wang, Chang Liu, Gavin R. Screaton, Elizabeth A. Clutterbuck, Aekkachai Tuekprakhon, Paola Cristina Resende, J Slon-Campos, S A Costa Clemens, Nigel J. Temperton, Duyvesteyn Hme., D W Crook, K Da Silva, T Malik
Publikováno v:
Cell
SARS-CoV-2 has undergone progressive change with variants conferring advantage rapidly becoming dominant lineages e.g. B.1.617. With apparent increased transmissibility variant B.1.617.2 has contributed to the current wave of infection ravaging the I
Autor:
Derek C. Macallan, David W Eyre, J Slon-Campos, Susannah Leaver, Jai S Bolton, Lian Lee, Jeremy Ratcliff, Kreepa Kooblall, Christopher J. Walker, Marc Turner, Beibei Wang, Judith Wellens, José Lourenço, Christina Dold, Sheila F Lumley, Paul M. Matthews, Hannah Klim, J K Baillie, George Carnell, Juthathip Mongkolspaya, Philip Hopkins, Piyada Supasa, Alexander J. Mentzer, Duncan Wyncoll, Lucas Stolle, Wanwisa Dejnirattisai, Susanna Dunachie, Miles W. Carroll, Nigel Temperton, E Barnes, Robert S. Paton, Prabhjeet Phalora, Sandra Belij-Rammerstorfer, Sunetra Gupta, Stephen Kennedy, Malcom G Semple, Teresa Lambe, Provine N, Tihana Bicanic, Matthew Edmans, Alex Fyfe, Gavin R. Screaton, Donal T. Skelly, Anna L McNaughton, Paul Klenerman, Craig Thompson, Cesar Lopez-Camacho, Peter J. M. Openshaw, Lisa Jarvis, Uri Obolski, A Howarth, Jonathan Youngs, Investigators I, Peter Simmonds, Jonathan Ball
SummaryIt is unclear whether prior endemic coronavirus infections affect COVID-19 severity. Here, we show that in cases of fatal COVID-19, antibody responses to the SARS-COV-2 spike are directed against epitopes shared with endemic beta-coronaviruses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1579a3ab0f83669ff17997dd56f633e9
https://doi.org/10.1101/2021.05.04.21256571
https://doi.org/10.1101/2021.05.04.21256571
Autor:
Aekkachai Tuekprakhon, Thomas S. Walter, Donal T. Skelly, Beibei Wang, Marilda M. Siqueira, Thomas A. Bowden, Miles W. Carroll, David Hall, Derrick W. Crook, Susanna Dunachie, Paola Cristina Resende, Julian C. Knight, David I. Stuart, Cesar Lopez-Camacho, Piyada Supasa, Rubin Hulswit, Tao Dong, Guido C. Paesen, J Slon-Campos, S Bibi, Amy Flaxman, Fernanda Nascimento, Neil G. Paterson, Chang Liu, Sarah C. Gilbert, Juthathip Mongkolsapaya, Mark A. Williams, Alex Pauvolid-Corrêa, Paul Klenerman, Sandra Belij-Rammerstorfer, Helen M. Ginn, Eleanor Barnes, Helen M. E. Duyvesteyn, D. Zhou, Teresa Lambe, Valdinete Alves do Nascimento, Elizabeth A. Clutterbuck, Cristiano Fernandes da Costa, Sue Ann Costa Clemens, M Bittaye, Felipe Gomes Naveca, R Levin, R Nutalai, Yuguang Zhao, Andrew J. Pollard, Elizabeth E. Fry, Wanwisa Dejnirattisai, Jingshan Ren, Alexander J. Mentzer, Gavin R. Screaton, Christina Dold
SummaryTerminating the SARS-CoV-2 pandemic relies upon pan-global vaccination. Current vaccines elicit neutralizing antibody responses to the virus spike derived from early isolates. However, new strains have emerged with multiple mutations: P.1 from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00d2b37eb132a5eabf182afef4de1e8d
https://doi.org/10.1101/2021.03.12.435194
https://doi.org/10.1101/2021.03.12.435194
Autor:
Derrick W. Crook, Eleanor Barnes, Naomi Coombes, D. Zhou, Jingshan Ren, Duyvesteyn Hme., Bassam Hallis, Alexander J. Mentzer, Christina Dold, Sheila F Lumley, Cesar Lopez-Camacho, Aekkachai Tuekprakhon, Elizabeth E. Fry, Guido C. Paesen, Thomas S. Walter, Donal T. Skelly, Beibei Wang, Helen M. Ginn, David I. Stuart, Chang Liu, Sandra Belij-Rammerstorfer, Julian C. Knight, Susanna Dunachie, Juthathip Mongkolsapaya, S Bibi, Teresa Lambe, Amy Flaxman, Sarah C. Gilbert, P Supasa, Wanwisa Dejnirattisai, Paul Klenerman, M Bittaye, Miles W. Carroll, Tao Dong, Sue Charlton, R Levin, R Nutalai, Yuguang Zhao, William James, Gavin R. Screaton, Kevin R. Bewley, Elizabeth A. Clutterbuck, J Slon-Campos, Andrew J. Pollard
Publikováno v:
Cell
The race to produce vaccines against SARS-CoV-2 began when the first sequence was published, and this forms the basis for vaccines currently deployed globally. Independent lineages of SARS-CoV-2 have recently been reported: UK–B.1.1.7, South Africa
Autor:
Aekkachai Tuekprakhon, Amy Flaxman, Sarah C. Gilbert, Mark A. Williams, Teresa Lambe, Guido C. Paesen, J Slon-Campos, Eleanor Barnes, William James, N Gent, Naomi Coombes, I Shaik, Sue Charlton, Andrew J. Pollard, Christina Dold, Sheila F Lumley, A Sienkiewicz, Bassam Hallis, Alexander J. Mentzer, D. Zhou, Elizabeth E. Fry, R Nutalai, Kerry J Godwin, Gavin R. Screaton, Cesar Lopez-Camacho, Kevin R. Bewley, Paul Klenerman, Elizabeth A. Clutterbuck, Miles W. Carroll, Wanwisa Dejnirattisai, S Bibi, Beibei Wang, Juthathip Mongkolsapaya, Susanna Dunachie, Sandra Belij-Rammerstorfer, Jingshan Ren, David R. Hall, R Levin, Thomas S. Walter, Donal T. Skelly, Natalie Baker, Helen M. Ginn, P Supasa, Tao Dong, Chang Liu, Neil G. Paterson, Yuguang Zhao, Julian C. Knight, Holly E. Humphries, M Bittaye, David I. Stuart, D W Crook, Duyvesteyn Hme.
Publikováno v:
Cell
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
SARS-CoV-2 has caused over 2M deaths in little over a year. Vaccines are being deployed at scale, aiming to generate responses against the virus spike. The scale of the pandemic and error-prone virus replication is leading to the appearance of mutant
Autor:
J Kenneth Baillie, Lian Lee, José Lourenço, Piyada Supasa, Beibei Wang, J Slon-Campos, Stephen Kennedy, Lisa Jarvis, Philippa C Matthews, Peter J. M. Openshaw, Isaric C Investigators, George Carnell, Eleanor Barnes, Jeremy Ratcliff, Duncan Wyncoll, Prabhjeet Phalora, Craig Thompson, Wanwisa Dejnirattisai, Marc Turner, Judith Wellens, Alex Fyfe, Kreepa Kooblall, Cesar Lopez-Camacho, Alison Howarth, Christopher J. Walker, Philip Hopkins, Nigel Temperton, Lucas Stolle, Gavin R. Screaton, Donal T. Skelly, Susannah Leaver, Alexander J. Mentzer, Jai S Bolton, Sunetra Gupta, Teresa Lambe, Susanna Dunachie, Robert S. Paton, Tihana Bicanic, Hannah Klim, Peter Simmonds, Jonathan Ball, Uri Obolski, Sandra Belij-Rammerstorfer, Jonathan Youngs, Juthathip Mongkolspaya, Nicholas M. Provine, Derek C. Macallan, David W Eyre, Malcolm G Semple, Anna L McNaughton, Paul Klenerman, Christina Dold, Sheila F Lumley, Miles W. Carroll, Matthew Edmans
Publikováno v:
SSRN Electronic Journal.
It is unclear whether prior endemic coronavirus infections affect COVID-19 severity. Here, we show that in cases of fatal COVID-19, antibody responses to the SARS-COV-2 spike are directed against epitopes shared with endemic beta-coronaviruses in the
Autor:
Neil G. Paterson, Rita E. Chen, Elizabeth E. Fry, Alex Fyfe, Christina Dold, Chang Liu, Gavin R. Screaton, Yanchun Peng, Julika Raedecke, Piyada Supasa, Javier Gilbert-Jaramillo, Alexander J. Mentzer, J Slon-Campos, Mark A. Williams, Thomas S. Walter, Guido C. Paesen, Julian C. Knight, Nigel J. Temperton, Donal T. Skelly, Miles W. Carroll, Sunetra Gupta, David I. Stuart, Kuan-Ying A. Huang, Wanwisa Dejnirattisai, Tao Dong, William James, Karen R. Buttigieg, Yuguang Zhao, Tiong Kit Tan, Baoling Ying, David R. Hall, R Levin, A Howe, James Brett Case, C. Alistair Seibert, Michael S. Diamond, Adam L. Bailey, Jingshan Ren, Beibei Wang, Natasha M. Kafai, Felicity K.R. Bertram, Helen M. Ginn, Andrew J. Pollard, Yun Song, Alain Townsend, Helen M. E. Duyvesteyn, Paul Klenerman, Naomi Coombes, Juthathip Mongkolspaya, D. Zhou, Craig Thompson, Cesar Lopez-Camacho, Daniel K. Clare
Publikováno v:
Cell
Antibodies are crucial to immune protection against SARS-CoV-2, with some in emergency use as therapeutics. Here we identify 377 human monoclonal antibodies (mAbs) recognizing the virus spike, and focus mainly on 80 that bind the receptor binding dom