Zobrazeno 1 - 10
of 620
pro vyhledávání: '"J Simes"'
Publikováno v:
Current Oncology, Vol 30, Iss 2, Pp 1844-1859 (2023)
Randomized controlled trials (RCTs) form a cornerstone of oncology research by generating evidence about the efficacy of therapies in selected patient populations. However, their implementation is often resource- and cost-intensive, and their general
Externí odkaz:
https://doaj.org/article/f972ab7231a445c7afcf6c83a6ea1751
Autor:
Rachael L. Morton, Haitham Tuffaha, Vendula Blaya-Novakova, Jenean Spencer, Carmel M. Hawley, Phil Peyton, Alisa Higgins, Julie Marsh, William J. Taylor, Sue Huckson, Amy Sillett, Kieran Schneemann, Anitha Balagurunanthan, Miranda Cumpston, Paul A. Scuffham, Paul Glasziou, Robert J. Simes
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-21 (2022)
Abstract Background Prioritisation of clinical trials ensures that the research conducted meets the needs of stakeholders, makes the best use of resources and avoids duplication. The aim of this review was to identify and critically appraise approach
Externí odkaz:
https://doaj.org/article/b4089f70c4d54f298d3e58d96d490d16
Autor:
P. L. Thompson, J. Hui, J. Beilby, L. J. Palmer, G. F. Watts, M. J. West, A. Kirby, S. Marschner, R. J. Simes, D. R. Sullivan, H. D. White, R. Stewart, A. M. Tonkin
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background It is unclear whether genetic variants identified from single nucleotide polymorphisms (SNPs) strongly associated with coronary heart disease (CHD) in genome-wide association studies (GWAS), or a genetic risk score (GRS) derived f
Externí odkaz:
https://doaj.org/article/96fab9ee494749348d0580cefb62476e
Autor:
R. Mercieca-Bebber, E. H. Barnes, K. Wilson, Z. Samoon, E. Walpole, T. Mai, S. Ackland, M. Burge, G. Dickie, D. Watson, J. Leung, T. Wang, R. Bohmer, D. Cameron, J. Simes, V. Gebski, M. Smithers, J. Thomas, J. Zalcberg, A. P. Barbour
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background AGITG DOCTOR was a randomised phase 2 trial of pre-operative cisplatin, 5 fluorouracil (CF) followed by docetaxel (D) with or without radiotherapy (RT) based on poor early response to CF, detected via PET, for resectable oesophage
Externí odkaz:
https://doaj.org/article/5175ef561fb242c7a77bef9cbd168170
Autor:
B Mihaylova, R Wu, C Williams, J Zhou, I Schlackow, J Emberson, C Reith, A Keech, J Robson, K Wilkinson, J Armitage, R Collins, A Gray, J Simes, C Baigent
Publikováno v:
European Heart Journal. 43
Background Cardiovascular disease (CVD) mortality has declined steadily over the last few decades across Europe and North America. Purpose To provide contemporary estimates of long-term effectiveness and cost-effectiveness of statin therapy in differ
Autor:
J Zhou, R Wu, C Williams, J Emberson, C Reith, A Keech, J Robson, K Wilkinson, J Armitage, R Collins, A Gray, J Simes, C Baigent, B Mihaylova
Publikováno v:
European Heart Journal. 43
Background Need for primary and secondary healthcare increases following cardiovascular disease (CVD) events but there is no data on comparative increases in costs. Purpose To estimate annual primary care and hospital inpatient costs associated with
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Monica Tang, Thomas John, R. J. Simes, Sallie-Anne Pearson, Craig R. Lewis, Chee Khoon Lee, Andrea L Schaffer
Publikováno v:
Journal of Geriatric Oncology. 12:930-936
Objectives Older adults constitute the majority of patients with lung cancer. However, they are under-represented in clinical trials as eligibility criteria often restrict enrolment based on comorbidities that are common with aging. We aimed to descr