Zobrazeno 1 - 10
of 156
pro vyhledávání: '"J Shell"'
Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library
Autor:
Devan J. Shell, Justin M. Rectenwald, Peter H. Buttery, Rebecca L. Johnson, Caroline A. Foley, Shiva K.R. Guduru, Mélanie Uguen, Juanita Sanchez Rubiano, Xindi Zhang, Fengling Li, Jacqueline L. Norris-Drouin, Matthew Axtman, P. Brian Hardy, Masoud Vedadi, Stephen V. Frye, Lindsey I. James, Kenneth H. Pearce
Publikováno v:
SLAS Discovery, Vol 27, Iss 8, Pp 428-439 (2022)
Methyl-lysine (Kme) reader domains are prevalent in chromatin regulatory proteins which bind post-translational modification sites to recruit repressive and activating factors; therefore, these proteins play crucial roles in cellular signaling and ep
Externí odkaz:
https://doaj.org/article/859446a01131470eb8e3880dae7658e0
Autor:
Mélanie Uguen, Yu Deng, Fengling Li, Devan J. Shell, Jacqueline L. Norris-Drouin, Michael A. Stashko, Suzanne Ackloo, Cheryl H. Arrowsmith, Lindsey I. James, Pengda Liu, Kenneth H. Pearce, Stephen V. Frye
Publikováno v:
bioRxiv
Increased expression and hyperactivation of the methyltransferase SETDB1 are commonly observed in cancer and central nervous system disorders. However, there are currently no reported SETDB1-specific methyltransferase inhibitors in the literature, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6935d47261a73543a1a18915cbf62a28
https://doi.org/10.1101/2023.05.10.539986
https://doi.org/10.1101/2023.05.10.539986
Autor:
Katie M. Slattery, Shona L. Halson, Brad Clark, Aaron J. Coutts, Stephanie J. Shell, James R. Broatch
Publikováno v:
International Journal of Sports Physiology and Performance. 16:1901-1904
Purpose: This study aimed to independently validate a wearable inertial sensor designed to monitor training and performance metrics in swimmers. Methods: A total of 4 male (21 [4] y, 1 national and 3 international) and 6 female (22 [3] y, 1 national
Autor:
Elisabeth J. Shell
Publikováno v:
Physician Assistant Clinics. 6:603-611
Autor:
Stephanie J. Shell, Katie Slattery, Brad Clark, James R. Broatch, Shona L. Halson, Aaron J. Coutts
This study aimed to define, develop, and validate a subjective scale of training quality. Two related studies were used to 1) define training quality and 2) develop and validate a subjective scale. Part One: a purposive sample of 15 sub-elite (i.e. n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2845fa7defb25583d42cd73756410b31
https://hdl.handle.net/10453/163855
https://hdl.handle.net/10453/163855
Akademický článek
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Publikováno v:
Journal of cleaner production. 349
Estimates of biofuel carbon intensity are uncertain and depend on modeled land use change (LUC) emissions. While analysts have focused on economic and agronomic assumptions affecting the quantity of land converted, researchers have paid less attentio
Autor:
Shona L. Halson, Aaron J. Coutts, Katie M. Slattery, Stephanie J. Shell, Brad Clark, Michael Kellmann, James R. Broatch
Publikováno v:
Journal of Sports Sciences. 38:2092-2099
This study aimed to investigate swimmer's use and coach prescription of recovery strategies during training and competition while examining perceived challenges, barriers, and beliefs in the importance of their effectiveness. A mixed-methods sequenti
Akademický článek
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Akademický článek
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