Zobrazeno 1 - 10
of 36
pro vyhledávání: '"J Shawn Justement"'
Autor:
Katherine E Clarridge, Jana Blazkova, Kevin Einkauf, Mary Petrone, Eric W Refsland, J Shawn Justement, Victoria Shi, Erin D Huiting, Catherine A Seamon, Guinevere Q Lee, Xu G Yu, Susan Moir, Michael C Sneller, Mathias Lichterfeld, Tae-Wook Chun
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006792 (2018)
Therapeutic strategies aimed at achieving antiretroviral therapy (ART)-free HIV remission in infected individuals are under active investigation. Considering the vast majority of HIV-infected individuals experience plasma viral rebound upon cessation
Externí odkaz:
https://doaj.org/article/45496f66b1e943179ffa52f4f100a017
Autor:
Steven A Yukl, Eli Boritz, Michael Busch, Christopher Bentsen, Tae-Wook Chun, Daniel Douek, Evelyn Eisele, Ashley Haase, Ya-Chi Ho, Gero Hütter, J Shawn Justement, Sheila Keating, Tzong-Hae Lee, Peilin Li, Danielle Murray, Sarah Palmer, Christopher Pilcher, Satish Pillai, Richard W Price, Meghan Rothenberger, Timothy Schacker, Janet Siliciano, Robert Siliciano, Elizabeth Sinclair, Matt Strain, Joseph Wong, Douglas Richman, Steven G Deeks
Publikováno v:
PLoS Pathogens, Vol 9, Iss 5, p e1003347 (2013)
There is intense interest in developing curative interventions for HIV. How such a cure will be quantified and defined is not known. We applied a series of measurements of HIV persistence to the study of an HIV-infected adult who has exhibited eviden
Externí odkaz:
https://doaj.org/article/4dda2501e0024779b943768fe1eb4deb
Autor:
Jennifer Hartt Meyers, J Shawn Justement, Claire W Hallahan, Eric T Blair, Yongming A Sun, M Angeline O'Shea, Gregg Roby, Shyam Kottilil, Susan Moir, Colin M Kovacs, Tae-Wook Chun, Anthony S Fauci
Publikováno v:
PLoS ONE, Vol 2, Iss 5, p e458 (2007)
Plasmacytoid dendritic cells (pDCs) are important mediators of innate immunity that act mainly through secretion of interferon (IFN)-alpha. Previous studies have found that these cells can suppress HIV in vitro; additionally, pDCs have been shown to
Externí odkaz:
https://doaj.org/article/d44c8696110246179f9b5da77b358390
Autor:
Michael C. Sneller, Jana Blazkova, J. Shawn Justement, Victoria Shi, Brooke D. Kennedy, Kathleen Gittens, Jekaterina Tolstenko, Genevieve McCormack, Emily J. Whitehead, Rachel F. Schneck, Michael A. Proschan, Erika Benko, Colin Kovacs, Cihan Oguz, Michael S. Seaman, Marina Caskey, Michel C. Nussenzweig, Anthony S. Fauci, Susan Moir, Tae-Wook Chun
Publikováno v:
Nature. 606:375-381
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1debf122b8165144c14fa8fd497e2b2
https://doi.org/10.1038/s41586-022-04797-9
https://doi.org/10.1038/s41586-022-04797-9
Autor:
Victoria Shi, Erika Benko, J. Shawn Justement, Paul A. Wender, Kathleen R. Gittens, Colin Kovacs, Michael C. Sneller, Susan Moir, Tae-Wook Chun, Erin D Huiting, Anthony S. Fauci, Jana Blazkova
Publikováno v:
J Infect Dis
Therapeutic strategies for achieving sustained virologic remission are being explored in human immunodeficiency virus (HIV)–infected individuals who began antiretroviral therapy (ART) during the early phase of infection. In the evaluation of such t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f8d5b559587885907029d01e8ffb9b
https://doi.org/10.1093/infdis/jiz100
https://doi.org/10.1093/infdis/jiz100
Autor:
Jana, Blazkova, Feng, Gao, Manukumar Honnayakanahalli, Marichannegowda, J Shawn, Justement, Victoria, Shi, Emily J, Whitehead, Rachel F, Schneck, Erin D, Huiting, Kathleen, Gittens, Mackenzie, Cottrell, Erika, Benko, Colin, Kovacs, Justin, Lack, Michael C, Sneller, Susan, Moir, Anthony S, Fauci, Tae-Wook, Chun
Publikováno v:
Nature medicine. 27(11)
Certain infected individuals suppress human immunodeficiency virus (HIV) in the absence of anti-retroviral therapy (ART). Elucidating the underlying mechanism(s) is of high interest. Here we present two contrasting case reports of HIV-infected indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::728a0d8ea668b7565a747ade4db12a43
https://pubmed.ncbi.nlm.nih.gov/34711975
https://pubmed.ncbi.nlm.nih.gov/34711975
Autor:
Cuiping Liu, Eric W. Refsland, Victoria Shi, Jana Blazkova, Tae-Wook Chun, Stephen D. Schmidt, John R. Mascola, Susan Moir, Erin D Huiting, J. Shawn Justement, Kathleen R. Gittens, Xuejun Chen, Alonso Heredia, Nicole A. Doria-Rose, Katherine E Clarridge
A number of highly potent and broadly neutralizing antibodies (bNAbs) against the human immunodeficiency virus (HIV) have recently been shown to prevent transmission of the virus, suppress viral replication, and delay plasma viral rebound following d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62b17d31725cd9f724c2bf71a339ae1
https://europepmc.org/articles/PMC6819136/
https://europepmc.org/articles/PMC6819136/
Autor:
J. Shawn Justement, Tae-Wook Chun, Ming Chang, Danielle Murray, Kenneth Tapia, Sarah Holte, James I. Mullins, Robert W. Coombs, Joanne D. Stekler, Ann C. Collier, Janine Maenza, Claire E. Stevens
Publikováno v:
BioResearch Open Access, Vol 5, Iss 1, Pp 15-21 (2016)
BioResearch Open Access
BioResearch Open Access
Availability of integrase strand transfer inhibitors created interest in determining whether their use would decrease persistently infected cell numbers. This study hypothesized that adding raltegravir (RAL) to standard antiretroviral therapy (ART) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92126543e44e3bb2b89d13a9ea48c95f
https://www.liebertpub.com/doi/10.1089/biores.2015.0038
https://www.liebertpub.com/doi/10.1089/biores.2015.0038
Autor:
Susan Moir, Lela Kardava, Peter D. Sun, Yuxing Li, J. Shawn Justement, Kathleen R. Gittens, Wei Wang, Richard Kwan, Valerie A. Melson, Gwynne Roth, Marissa A. Hand, James W. Austin, Clarisa M. Buckner, Haewon Sohn, Christine Youn, Michael C. Sneller, Tae-Wook Chun, Susan K. Pierce
Immunoglobulin G3 (IgG3) has an uncertain role in the response to infection with and vaccination against human immunodeficiency virus (HIV). Here we describe a regulatory role for IgG3 in dampening the immune system–activating effects of chronic HI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c81c6c580eff8d7fb3ea246a8eeb8b
https://europepmc.org/articles/PMC6289069/
https://europepmc.org/articles/PMC6289069/
Autor:
Daryl E. Morris, John H. Eldridge, Tae-Wook Chun, Michael A. Proschan, Richard Kwan, Victoria Shi, Erika Benko, Eric W. Refsland, Michael A. Egan, Colin Kovacs, Susan Moir, J. Shawn Justement, Katherine E Clarridge, Kathleen R. Gittens, Kristen W. Cohen, Jana Blazkova, M. Juliana McElrath, Michael C. Sneller, Mary E. Petrone, Rong Xu, Anthony S. Fauci
Publikováno v:
Science translational medicine. 9(419)
Despite substantial clinical benefits, complete eradication of HIV has not been possible using antiretroviral therapy (ART) alone. Strategies that can either eliminate persistent viral reservoirs or boost host immunity to prevent rebound of virus fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01aef1ed1a79ca38a616814427efa77f
https://pubmed.ncbi.nlm.nih.gov/29212716
https://pubmed.ncbi.nlm.nih.gov/29212716