Zobrazeno 1 - 10
of 319
pro vyhledávání: '"J Seelbach"'
Publikováno v:
Einheit in Vielfalt.
Publikováno v:
Clinical Hemorheology and Microcirculation. 60:25-37
BACKGROUND Poly(N-isopropylacrylamide) conjugated hyaluronan (HA-pN), a brush-like copolymer system which serves as a polymer vehicle for cellular and drug delivery, has been previously synthesized via the copper catalyzed azide-alkyne reaction (CuAA
Autor:
Fernando Albericio, Peter Paul K.H. Fransen, Mauro Alini, Philipp Niemeyer, Alvaro Mata, Daniel Pulido, Thomas M. Freiman, Sebastian Sauerbier, Miriam Royo, Fabian Duttenhoefer, Matteo D'Este, David Eglin, Ryan J. Seelbach
Publikováno v:
Macromolecular Bioscience. 15:1035-1044
BMP-2 and TGF-β1 released from injectable thermoresponsive hydrogels are studied in the presence and absence of branched macromolecules bearing BMP-2 or TGF-β1 affinity binding peptides. The synthesized branched macromolecules and the gelling compo
Autor:
Alvaro Mata, Marianna Peroglio, David Eglin, Patricia López-Chicón, Philipp Niemeyer, Ryan J. Seelbach, Peter Fransen, Miriam Royo, Fernando Albericio, Carlos E. Semino, Fabian Duttenhoefer, Mauro Alini, Thomas M. Freiman, Daniel Pulido, Sebastian Sauerbier
Publikováno v:
Acta Biomaterialia. 10:4340-4350
The controlled presentation of biofunctionality is of key importance for hydrogel applications in cell-based regenerative medicine. Here, a versatile approach was demonstrated to present clustered binding epitopes in an injectable, thermoresponsive h
Autor:
Yean Jung Choi, Hong Pu, Melissa J. Seelbach, Bernhard Hennig, Michal Toborek, Lei Chen, Bei Zhang, Sung Yong Eum
Publikováno v:
Environmental Health Perspectives
Background Polychlorinated biphenyls (PCBs) are widely distributed environmental toxicants that contribute to numerous disease states. The main route of exposure to PCBs is through the gastrointestinal tract; however, little is known about the effect
Autor:
Bei Zhang, Lei Chen, Bernhard Hennig, Wen Huang, Geun Bae Rha, Ibolya E. András, Dennis Bruemmer, Michal Toborek, Melissa J. Seelbach
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 298:H1136-H1145
Telomerase, via its catalytic component telomerase reverse transcriptase (TERT), extends telomeres of eukaryotic chromosomes. The importance of this reaction is related to the fact that telomere shortening is a rate-limiting mechanism for human life
Autor:
Yean Jung Choi, Michal Toborek, Lei Chen, Anita Powell, Bernhard Hennig, Melissa J. Seelbach, Bei Zhang
Publikováno v:
Environmental Health Perspectives
Background Polychlorinated biphenyls (PCBs) comprise a ubiquitous class of toxic substances associated with carcinogenic and tumor-promoting effects as well as neurotoxic properties in the brain. However, the effects of PCBs on the development of tum
Publikováno v:
Journal of Neurochemistry. 102:1677-1690
P-glycoprotein (Pgp, ABCB1) is a critical efflux transporter at the blood-brain barrier (BBB) where its luminal location and substrate promiscuity limit the brain distribution of numerous therapeutics. Moreover, Pgp is known to confer multi-drug resi
Autor:
Ryan J, Seelbach, Peter, Fransen, Daniel, Pulido, Matteo, D'Este, Fabian, Duttenhoefer, Sebastian, Sauerbier, Thomas M, Freiman, Philipp, Niemeyer, Fernando, Albericio, Mauro, Alini, Miriam, Royo, Alvaro, Mata, David, Eglin
Publikováno v:
Macromolecular bioscience. 15(8)
BMP-2 and TGF-β1 released from injectable thermoresponsive hydrogels are studied in the presence and absence of branched macromolecules bearing BMP-2 or TGF-β1 affinity binding peptides. The synthesized branched macromolecules and the gelling compo
Autor:
Rachael A. Charles, Tracy A. Brooks, Richard D. Egleton, Scott M. Ocheltree, Melissa J. Seelbach, Nicole Nametz, Thomas P. Davis
Publikováno v:
Brain Research. 1120:172-182
The blood–brain barrier (BBB) is a dynamic system which maintains brain homeostasis and limits CNS penetration via interactions of transmembrane and intracellular proteins. Inflammatory pain (IP) is a condition underlying several diseases with know