Zobrazeno 1 - 10
of 157
pro vyhledávání: '"J Schmitges"'
Autor:
F Abdollah, M Sun, SF Shariat, J Schmitges, O Djahangirian, Z Tian, C Jeldres, P Perrotte, F Montorsi, PI Karakiewicz
Publikováno v:
International Brazilian Journal of Urology, Vol 37, Iss 3, Pp 413-414 (2011)
Externí odkaz:
https://doaj.org/article/bf547f1db8784df5a5023fd2e636f45b
Publikováno v:
Nachrichten aus Chemie, Technik und Laboratorium. 45:1105-1108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::744180a7041fd4952746eb24d6d2c6bc
https://doi.org/10.1002/nadc.199700030
https://doi.org/10.1002/nadc.199700030
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(4)
The discovery, synthesis and structure-activity relationships of a series of novel benzofuro[3,2-b]pyridines as non-selective endothelin ET(A)/ET(B) as well as selective ET(B) receptor antagonists are described. The most potent non-selective inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29a4bbada3ab997098be65f62a564921
https://pubmed.ncbi.nlm.nih.gov/10098676
https://pubmed.ncbi.nlm.nih.gov/10098676
Autor:
W W, Mederski, D, Dorsch, M, Osswald, S, Anzali, M, Christadler, C J, Schmitges, P, Schelling, C, Wilm, M, Fluck
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(13)
The discovery, in vitro and in vivo studies of the highly potent ETA antagonist EMD 122946 are presented. This compound displayed high binding affinity and functional antagonism [IC50 = 3.2 x 10(-11) M, pA2 = 9.5 (ETA)] and inhibited the ET-1 induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72da73ed675d2c33b7056c9c602042fa
https://pubmed.ncbi.nlm.nih.gov/9873432
https://pubmed.ncbi.nlm.nih.gov/9873432
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(1)
The methylendioxyphenyl group is present in a number of endothelin receptor antagonists thus far reported. By means of a Kohonen neural network we discovered with a benzothiadiazole a bioisosteric replacement instead. This group should be devoid of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::675a094897a2c9eada9e5012506ba5be
https://pubmed.ncbi.nlm.nih.gov/9871621
https://pubmed.ncbi.nlm.nih.gov/9871621
Publikováno v:
European Urology Supplements. 10:119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d57757e91169d4b21d6eb50bf3f7384
https://doi.org/10.1016/s1569-9056(11)60319-9
https://doi.org/10.1016/s1569-9056(11)60319-9
Autor:
M. Sun, F. Abdollah, C. Jeldres, J. Schmitges, O. Djahangirian, D. Liberman, S. Ismail, Z. Tian, S.F. Shariat, P.I. Karakiewicz
Publikováno v:
European Urology Supplements. 10:200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b13c2aff2c2236ab5952b99fbeef420a
https://doi.org/10.1016/s1569-9056(11)60605-2
https://doi.org/10.1016/s1569-9056(11)60605-2
Publikováno v:
Advances in experimental medicine and biology. 306
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d58aad96204eab49e5488acbf01e16cc
https://pubmed.ncbi.nlm.nih.gov/1812733
https://pubmed.ncbi.nlm.nih.gov/1812733
Autor:
Claus J. Schmitges, Robert D. Deeprose, Gail S. Duncan, Thomas P. Zimmerman, Gertrude B. Elion, Gerald Wolberg, Pedro Cuatrecasas
Publikováno v:
Proceedings of the National Academy of Sciences. 77:5639-5643
Mouse lymphocytes incubated with micromolar concentrations of adenosine or 3-deazaadenosine, in medium supplemented with L-homocysteine, rapidly accumulated supramillimolar concentrations of S-adenosylhomocysteine (AdoHcy) or S-3-deazaadenosylhomocys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea742a6f9e8ec929d026f4b3e8e1934
https://doi.org/10.1073/pnas.77.10.5639
https://doi.org/10.1073/pnas.77.10.5639
Publikováno v:
Life Sciences. 19:1971-1979
A naturally occurring compound, 2'-deoxyadenosine-3'-monophosphate (2'-deoxy-3'-AMP), is a potent inhibitor (K i about 10 μM) of the adenylate cuclase activity of various rat tissues, toad erythrocytes, and mammalian cells in culture. This inhibitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f7ff96e551fd807a6a7d037c0e312b
https://doi.org/10.1016/0024-3205(76)90133-8
https://doi.org/10.1016/0024-3205(76)90133-8