Výsledky vyhledávání - "J S Ungerstedt"

Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors

Autor: J. S. Ungerstedt, Paul A. Marks, Y. Shao, Arne Holmgren, Weisheng Xu, G. Perez, Y. Sowa, X. Jiang, Lang Ngo, Milos Dokmanovic

Publikováno v: Proceedings of the National Academy of Sciences. 102:673-678

This study examines the basis of resistance and sensitivity of normal and transformed cells to histone deacetylase inhibitor (HDACi)-induced cell death, specifically the role of caspases and thioredoxin (Trx). An important attribute of HDACis is that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f054ca051ea595ef88a172c91cb62a0
https://doi.org/10.1073/pnas.0408732102

Zobrazit plný text záznamu

Nicotinamide inhibits endotoxin-induced monocyte tissue factor expression

Autor: T Söderström, J S Ungerstedt, K Heimersson, M Hansson

Publikováno v: Journal of Thrombosis and Haemostasis. 1:2554-2560

Summary. Background: Tissue factor (TF) is the main initiator of blood coagulation in vivo. Its increased expression on activated monocytes is associated with thrombotic complications and mortality in conditions such as sepsis, disseminated intravasc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66714e5561d2d6cf65d30a2c04c99630
https://doi.org/10.1046/j.1538-7836.2003.00463.x

Zobrazit plný text záznamu

Autologous hematopoietic stem cell transplantation in multiple myeloma and lymphoma: an analysis of factors influencing stem cell collection and hematological recovery

Autor: Astrid Gruber, J. S. Ungerstedt, Hareth Nahi, Katarina Uttervall, Per Ljungman, Emma Watz, B. M Johansson, Björn E. Wahlin, U. Axdorph Nygell, Per Näsman

Publikováno v: Medical oncology (Northwood, London, England). 29(3)

Autologous stem cell transplantation is standard treatment for newly diagnosed younger patients with multiple myeloma and for relapsed or refractory Hodgkin or non-Hodgkin lymphoma. Patient characteristics influencing the yield from stem cell collect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464d9e771b81918cbf7d560e690cc913
https://pubmed.ncbi.nlm.nih.gov/21779930

Zobrazit plný text záznamu

Hemorrhagic symptoms and bleeding risk in obligatory carriers of type 3 von Willebrand disease: an international, multicenter study

Autor: P. Petrini, A. Cappelletti, A. Srivastava, Alberto Tosetto, Francesco Baudo, J. S. Ungerstedt, M. Nishino, Jeroen Eikenboom, Augusto B. Federici, Stefan Lethagen, F. Rodeghiero, S. Linari, J. M. Lusher, Giancarlo Castaman

Publikováno v: Journal of thrombosis and haemostasis : JTH. 4(10)

Objectives: We undertook an international, multicenter study to describe the clinical picture and to estimate the bleeding risk in a group of obligatory carriers of type 3 von Willebrand disease (VWD). Patients and methods: Obligatory carriers (OC) o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96b5252be1a769af269916652b15be5
https://pubmed.ncbi.nlm.nih.gov/16889558

Zobrazit plný text záznamu

Nicotinamide is a potent inhibitor of proinflammatory cytokines

Autor: T. Söderström, J. S. Ungerstedt, M. Blombäck

Publikováno v: Clinical and experimental immunology. 131(1)

SUMMARY The present study investigates the modulating effects of nicotinamide on the cytokine response to endotoxin. In an in vitro model of endotoxaemia, human whole blood was stimulated for two hours with endotoxin at 1 ng/ml, achieving high levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffd278dc4580d7b6c35f690a4ff4fdf
https://pubmed.ncbi.nlm.nih.gov/12519385

Zobrazit plný text záznamu

Measurement of blood and plasma coagulation time using free oscillating rheometry

Autor: Margareta Blombäck, J S Ungerstedt, Anders Kallner

Publikováno v: Karolinska Institutet

An assay based on free oscillating rheometry to measure the activity of coagulation factors is described. The method can be used in blood and plasma and is particularly suitable for screening and monitoring coagulation disturbances in point-of-care t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3c866e24e0f6a2e34f856bd154992e
https://pubmed.ncbi.nlm.nih.gov/12004929

Zobrazit plný text záznamu