Zobrazeno 1 - 10
of 168
pro vyhledávání: '"J S Remington"'
Autor:
C A Hunter, L Ellis-Neyer, K E Gabriel, M K Kennedy, K H Grabstein, P S Linsley, J S Remington
Publikováno v:
The Journal of Immunology. 158:2285-2293
We examined the role of the CD28/B7 interaction in regulation of NK cell activity. Cells transfected with B7 enhanced IL-12-induced production of IFN-gamma by IL-2-activated, CD28+ NK cells, but not by resting CD28- NK cells. The ability of B7 transf
Publikováno v:
The Journal of Immunology. 157:2564-2569
IFN-gamma is critical for prevention of development of toxoplasmic encephalitis (TE). Since IL-4 down-regulates production of IFN-gamma, we examined its role in the pathogenesis of TE in IL-4-targeted mutant (IL-4-/-) mice. IL-4-/- mice all died from
Publikováno v:
The Journal of Immunology. 155:4347-4354
Mice with the severe combined immunodeficiency (SCID) possess an IFN-gamma-dependent mechanism of resistance to the intracellular pathogens Toxoplasma gondii and Listeria monocytogenes that is dependent on IL-12-induced production of IFN-gamma by NK
Publikováno v:
The Journal of Immunology. 153:4649-4654
Previous studies revealed that mice with the b or k allele at the H-2D region are susceptible to toxoplasmic encephalitis (TE); those with the d allele are resistant. To determine whether the b or d allele is dominant, F1 hybrids between susceptible
Publikováno v:
The Journal of Immunology. 153:4583-4587
Toxoplasma gondii is a major pathogen of immunocompromised hosts, and one defense mechanism against the parasite is activation of macrophages (M phi) for toxoplasmacidal activity by IFN-gamma after triggering by TNF-alpha. IL-6, IFN-gamma, and TNF-al
Publikováno v:
The Journal of Immunology. 150:3404-3410
Microglia may play a role in host defense against Toxoplasma gondii in the central nervous system. In our study, the antitoxoplasma activity of murine microglia was investigated. T. gondii multiplied readily in cultured microglial cells, and activati
Publikováno v:
Journal of Clinical Microbiology. 30:3000-3002
The polymerase chain reaction (PCR) was used to detect Toxoplasma gondii DNA in cerebrospinal fluid (CSF) from 14 patients with AIDS by amplification of the repetitive B1 gene. Positive PCRs were obtained in CSF from four of nine patients with toxopl
Autor:
Y Suzuki, J S Remington
Publikováno v:
Journal of Clinical Microbiology. 28:2354-2356
Titers in a direct agglutination test using Formalin-fixed toxoplasma tachyzoites were significantly higher in patients with acquired immunodeficiency syndrome with toxoplasmic encephalitis (TE) than in those without TE. In contrast, when fresh (not
Autor:
Y Suzuki, J S Remington
Publikováno v:
The Journal of Immunology. 144:1954-1956
The effect of an IFN-gamma mAb on the protective activity of immune T cells against Toxoplasma infection was examined in a murine model of toxoplasmosis. Mice that received anti-IFN-gamma antibody and immune spleen cells all died of toxoplasmosis aft
Publikováno v:
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 17(3)
We report a case of fatal central nervous system infection with Scedosporium apiospermum (Pseudallescheria boydii) in a heart transplant recipient. This ubiquitous fungus is known to cause mycetoma and localized infections in patients with otherwise