Zobrazeno 1 - 10
of 95
pro vyhledávání: '"J S McDougal"'
Autor:
A. S. Abdullahi, C. Adje-Toure, Adrian Puren, L. Marum, J. W. Hargrove, M. Y. Borget-Alloue, J. S. McDougal, V. Pillay-Van Wyk, A. K. Ekra, Bharat Parekh, L. Odawo, Thomas Rehle, Andrea A. Kim
Publikováno v:
AIDS Research and Human Retroviruses. 26:1051-1061
Serological assays for estimating HIV-1 incidence are prone to misclassification, limiting the accuracy of the incidence estimate. Adjustment factors have been developed and recommended for estimating assay-based HIV-1 incidence in cross-sectional se
Publikováno v:
AIDS Research and Human Retroviruses. 15:435-443
New therapeutic regimens have dramatically altered morbidity and mortality attributed to HIV-1 infection. Changes in lymphocyte subsets after treatment may mirror salutary clinical changes. Over 4 months we analyzed lymphocyte subsets in 20 patients
Autor:
Eng M. Tan, Doyt Conn, Joachim R. Kalden, James A. Koziol, Josef S. Smolen, Robert G. Lahita, Naomi F. Rothfield, Ruud J.T. Smeenk, John A. Hardin, J. S. McDougal, Merlin R. Wilson, Ravinder N. Maini, Marvin J. Fritzler, Yoshinari Takasaki, Brian T. Butcher, Roger L. Dawkins, Walther J. van Venrooij, Allan Wiik, Tom P. Gordon
Publikováno v:
Arthritis & Rheumatism. 42:455-464
Objective To determine the performance characteristics of enzyme-based immunoassay (EIA) kits for the detection of antinuclear and other autoantibodies of defined specificities. Methods Nine manufacturers of EIA kits to detect antibodies of defined s
Autor:
Joachim R. Kalden, Brian T. Butcher, Tom P. Gordon, James A. Koziol, Yoshinari Takasaki, Josef S. Smolen, Robert G. Lahita, T. E. W. Feltkamp, Eng M. Tan, Ravinder N. Maini, Roger L. Dawkins, J. S. McDougal, Merlin R. Wilson, Allan Wiik, Marvin J. Fritzler, John A. Hardin, Naomi F. Rothfield, Ruud J.T. Smeenk
Publikováno v:
Arthritis & Rheumatism. 40:1601-1611
Objective. To determine the range of antinuclear antibodies (ANA) in “healthy” individuals compared with that in patients with systemic lupus erythematosus (SLE), systemic sclerosis (SSc; scleroderma), Sjogren's syndrome (SS), rheumatoid arthriti
Publikováno v:
Journal of Virology. 70:5236-5245
An assay for the neutralization of human immunodeficiency virus type 1 (HIV-1) is described in which the reduction in infectious titer of HIV-1 after preincubation at 37 degrees C with antibody-positive serum is the measure of neutralization. The ass
Cross-reactivity of 75 monoclonal antibodies to human immunoglobulin with sera of non-human primates
Publikováno v:
Immunology Letters. 37:207-213
We systematically analyzed a panel of 75 murine monoclonal antibodies (mAbs) reactive with human immunoglobulins IgG, IgA, IgM, IgD, and kappa and lambda light chains for reactivity with serum immunoglobulins of higher primates. In the great apes, an
Publikováno v:
Journal of Human Lactation. 9:13-17
Human milk was inoculated with human immunodeficiency virus type I (HIV-1) or with HIV-1-infected cells in volumes and containers typically used in human milk banks. The inoculated milk was pasteurized at 62.5°C for 30 minutes in a water bath, i.e.,
Publikováno v:
AIDS Research and Human Retroviruses. 7:975-981
We tested human immunodeficiency virus type 1 (HIV-1) antibody-positive human sera and sCD4, alone and in combination, for synergistic, additive, or antagonistic effects on blocking of HIV binding and infectivity. Data were analyzed by an application
Publikováno v:
Current Opinion in Immunology. 3:552-558
The three-dimensional structure of the binding domain of the CD4 molecule has been determined and extensive mutational analyses of the respective binding sites on gp120 and CD4 have been completed. The consequences of gp120-CD4 binding with respect t
Publikováno v:
The Journal of Immunology. 146:2578-2587
Receptor binding of HIV to the CD4 molecule is required for efficient infection of T cells, but the post-binding steps that result in penetration of HIV are not well understood. CD4 is induced to internalize upon T cell activation, and mAb to CD4 mod