Výsledky vyhledávání - "J S Manavalan"

Akademický článek

P1278: ACTIVATION OF THE NECROPTOSIS PATHWAY PLAYS A ROLE IN SYNERGISM WITH COMBINATION OF THE IAP ANTAGONIST, TOLINAPANT AND HYPOMETHYLATING AGENTS (HMA) IN IN VITRO MODELS OF T-CELL LYMPHOMA (TCL).

Autor: J. S. Manavalan, MD, I. Pal, PhD, A. Pursley, G. Ward, PhD, T. Smyth, PhD, M. Sims, PhD, D. Feith, PhD, T. P. Loughran, Jr, MD, O. A. O’Connor, MD, PhD, E. Marchi, MD, PhD

Publikováno v: HemaSphere, Vol 6, Pp 1163-1164 (2022)

Externí odkaz: https://doaj.org/article/c5043f7c27a345209abffa6fbe7b4082

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Cellular Basis of B Cell Clonal Populations in Old Mice

Autor: J, LeMaoult, J S, Manavalan, R, Dyall, P, Szabo, J, Nikolic-Zugic, M E, Weksler

Publikováno v: The Journal of Immunology. 162:6384-6391

Previous studies from this laboratory have shown that >85% of old mice have stable B cell clonal populations detectable by Ig heavy chain complementary-determining region 3 mRNA size analysis and confirmed by sequence analysis. B cells from the same

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79cf904b509911c12b2c09321c734b9a
https://doi.org/10.4049/jimmunol.162.11.6384

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Expanded CD4+ and CD8+ T cell clones in elderly humans

Autor: R Schwab, P Szabo, J S Manavalan, M E Weksler, D N Posnett, C Pannetier, P Kourilsky, J Even

Publikováno v: The Journal of Immunology. 158:4493-4499

The diversity of the human TCR repertoire in aging has been studied by examining the profiles of complementarity-determining region 3 (CDR3) sizes expressed by the BV families. The TCRBV CDR3 profile, which shows size heterogeneity in young adult hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca8c26b38162bfcd339ccd78f0139822
https://doi.org/10.4049/jimmunol.158.9.4493

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Abnormal T-cell repertoire is consistent with immune process underlying the pathogenesis of paroxysmal nocturnal hemoglobinuria

Autor: A, Karadimitris, J S, Manavalan, H T, Thaler, R, Notaro, D J, Araten, K, Nafa, I A, Roberts, M E, Weksler, L, Luzzatto

Publikováno v: Blood. 96(7)

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal disorder of the hematopoietic stem cell (HSC). Somatic mutations in the PIG-A gene result in the deficiency of several glycosylphosphatidylinositol-linked proteins from the surface of bl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a2baf41c310cbd1d24b7b7f3c711f33c
https://pubmed.ncbi.nlm.nih.gov/11001919

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