Zobrazeno 1 - 10
of 19
pro vyhledávání: '"J S Crowe"'
Autor:
J. S. H. Gaston, M. Hurle, A. Wong, Charles J. Cox, S. Wilkie, J. S. Crowe, E. D. Zanders, K. E. Kempsell
Publikováno v:
Infection and Immunity. 68:6012-6026
Onset of rheumatoid arthritis (RA) is widely believed to be preceded by exposure to some environmental trigger such as bacterial infectious agents. The influence of bacteria on RA disease onset or pathology has to date been controversial, due to inco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f99e90409e7b5780f999c6b926c3c7
https://doi.org/10.1128/iai.68.10.6012-6026.2000
https://doi.org/10.1128/iai.68.10.6012-6026.2000
Autor:
A Dalgleish, K Singh, A M Deakin, R J Leicester, J H Ellis, C J Finlayson, W F A Miles, P F Life, J S Crowe
Publikováno v:
Clinical and Experimental Immunology. 118:197-204
SUMMARYLoss of the T cell receptor-associated CD3 ζ chain has been proposed as a possible mechanism of the acquired immunosuppression in both tumour-bearing hosts, and in symptomatic patients with HIV infection. However, other reports suggest that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9873949f1aa772a4a2e278255aa2a6
https://doi.org/10.1046/j.1365-2249.1999.01044.x
https://doi.org/10.1046/j.1365-2249.1999.01044.x
Publikováno v:
The Journal of Immunology. 156:2700-2709
CD80 and CD86 are cell surface glycoproteins expressed on a variety of professional APCs. They have attracted much attention due to their function as potent costimulators of T lymphocyte function through their interaction with CD28 and possibly CTLA4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee7289c0e168e1e668d1ea763d6eb246
https://doi.org/10.4049/jimmunol.156.8.2700
https://doi.org/10.4049/jimmunol.156.8.2700
Publikováno v:
The Journal of Immunology. 155:925-937
Multiple myeloma is a malignancy of plasma cells for which there is no effective treatment. To develop an immunotherapeutic agent, we have raised a high affinity mAb (AT13/5) against CD38, one of the few well-characterized surface Ags present on myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44b26ebc42b31b8c2accab75df55a0ea
https://doi.org/10.4049/jimmunol.155.2.925
https://doi.org/10.4049/jimmunol.155.2.925
Autor:
A P Lewis, S M Lemon, K A Barber, P Murphy, N R Parry, T C Peakman, M J Sims, J Worden, J S Crowe
Publikováno v:
The Journal of Immunology. 151:2829-2838
A human anti-hepatitis A virus mAb was rescued from a hybridoma cell line by conventional cDNA cloning, and expressed in CHO cells. The full nucleotide sequences of the mAb H and L chains were determined, revealing a VHI/V lambda II V region combinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f75741b68edbed7ee093ab32a2b30c5d
https://doi.org/10.4049/jimmunol.151.5.2829
https://doi.org/10.4049/jimmunol.151.5.2829
Autor:
J M, Kupsch, N H, Tidman, N V, Kang, H, Truman, S, Hamilton, N, Patel, J A, Newton Bishop, I M, Leigh, J S, Crowe
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(4)
A human single-chain Fv (scFv) library as fusion to phage was constructed from donors with a high titer of autoantibodies. The library was subjected to three rounds of positive selection on human melanoma cells and negative selection on human periphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b44f49475c83bd7ca1fc2adcfd4aa04b
https://pubmed.ncbi.nlm.nih.gov/10213230
https://pubmed.ncbi.nlm.nih.gov/10213230
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(8)
CD80 and CD86 are cell surface glycoproteins expressed on a variety of professional APCs. They have attracted much attention due to their function as potent costimulators of T lymphocyte function through their interaction with CD28 and possibly CTLA4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b348a27c9c4b8de99c325a64b4cf6de4
https://pubmed.ncbi.nlm.nih.gov/8609386
https://pubmed.ncbi.nlm.nih.gov/8609386
Publikováno v:
Cancer research. 55(18)
We have examined the ability of melanoma cell lines and normal human melanocytes, which have demonstrable intact IFN genes, to secrete both IFN-alpha and IFN-beta in response to induction with virus. Normal melanocytes were found to secrete both IFN-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be9d466b6d964effa4963d33ac961e51
https://pubmed.ncbi.nlm.nih.gov/7664286
https://pubmed.ncbi.nlm.nih.gov/7664286
Autor:
J H, Ellis, K A, Barber, A, Tutt, C, Hale, A P, Lewis, M J, Glennie, G T, Stevenson, J S, Crowe
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(2)
Multiple myeloma is a malignancy of plasma cells for which there is no effective treatment. To develop an immunotherapeutic agent, we have raised a high affinity mAb (AT13/5) against CD38, one of the few well-characterized surface Ags present on myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e8be96d9db5c2759f839473f7c55411
https://pubmed.ncbi.nlm.nih.gov/7608568
https://pubmed.ncbi.nlm.nih.gov/7608568
Autor:
T C, Peakman, J, Worden, R H, Harris, H, Cooper, J, Tite, M J, Page, D R, Gewert, M, Bartholemew, J S, Crowe, S, Brett
Publikováno v:
Human antibodies and hybridomas. 5(1-2)
We report a detailed comparison of two commonly used stable, amplifiable mammalian expression systems (Chinese Hamster Ovary cells/dihydrofolate reductase and Mouse NSO myeloma/glutamine synthetase) used to express a humanized IgG1 monoclonal antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::734e504b0049010fbef83ae0e720733d
https://pubmed.ncbi.nlm.nih.gov/7532024
https://pubmed.ncbi.nlm.nih.gov/7532024