Zobrazeno 1 - 10
of 29
pro vyhledávání: '"J S, Verbeek"'
Autor:
L. van Beek, J. Van den Bossche, M. de Winther, J S Verbeek, Frits Koning, K. Willems van Dijk, Patrick C.N. Rensen, Mariëtte R. Boon, S M van den Berg, A D van Dam, Amanda C. M. Pronk, Vanessa van Harmelen, C. van Kooten
Publikováno v:
International Journal of Obesity, 42(2), 260-269. Nature Publishing Group
International journal of obesity (2005), 42(2), 260-269. Nature Publishing Group
International Journal of Obesity, 42(2), 260-269
International journal of obesity (2005), 42(2), 260-269. Nature Publishing Group
International Journal of Obesity, 42(2), 260-269
BACKGROUND/OBJECTIVES: In obesity, B cells accumulate in white adipose tissue (WAT) and produce IgG, which may contribute to the development of glucose intolerance. IgG signals by binding to Fc gamma receptors (Fc gamma R) and by activating the compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa93fa6af3c01d1e08ac7eb8d805b4ad
https://research.vumc.nl/en/publications/3793dd5d-39c6-44d9-907c-a97688087817
https://research.vumc.nl/en/publications/3793dd5d-39c6-44d9-907c-a97688087817
Autor:
M.H. van den Bosch, I. Di Ceglie, G. Ascone, P.L.E.M. van Lent, J. S. Verbeek, P.M. van der Kraan
Publikováno v:
Poster Presentations.
Background FcγRs are involved in regulation of synovial activation and bone destruction during immune complex (IC)-mediated arthritis. The balance between activating FcγRs (FcγRI,III and IV) and inhibiting FcγRII determines synovial activation. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8b02ae14d9042385eb153983d9fc182
https://doi.org/10.1136/annrheumdis-2017-eular.5386
https://doi.org/10.1136/annrheumdis-2017-eular.5386
Autor:
J. S. Verbeek, T. Rispens, Jan Voorberg, Aleksandra Wroblewska, Falk Nimmerjahn, A. ten Brinke, Ivan Peyron, J. W. Claassens, Robin B. Hartholt, Eszter Herczenik, Edith Slot, Martijn A. Nolte
Publikováno v:
Journal of thrombosis and haemostasis, 15(2), 329-340. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 15(2), 329-340
Journal of Thrombosis and Haemostasis, 15(2), 329-340
Essentials Anti-factor (F) VIII antibody formation is a major complication in the treatment of hemophilia A. We investigated uptake of FVIII and FVIII immune complex by bone marrow derived dendritic cells. Immune complex formation increased uptake of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72006a1e5cfdbe923c991b3839e0ad2
https://pubmed.ncbi.nlm.nih.gov/27868337
https://pubmed.ncbi.nlm.nih.gov/27868337
Autor:
J. Westermann, C. Schiller, Dirk Meyer, J. S. Verbeek, W. L. Hazenbos, R. E. Schmidt, Shozo Izui, J.E. Gessner
Publikováno v:
Blood. 92:3997-4002
In autoimmune hemolytic anemia (AIHA), there is accumulating evidence for an involvement of FcγR expressed by phagocytic effector cells, but demonstration of a causal relationship between individual FcγRs and IgG isotypes for disease development is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4fa8e18c10fc3c241288bd49507a1fc
https://doi.org/10.1182/blood.v92.11.3997
https://doi.org/10.1182/blood.v92.11.3997
Autor:
Takashi Saito, S. Y. Park, J. S. Verbeek, J.G.J. van de Winkel, C. Ra, Peter J.A. Capel, M. van Vugt, I. A. F. M. Heijnen
Publikováno v:
Blood. 87:3593-3599
Most Ig receptors exist as hetero-oligomeric complexes with separate ligand binding (alpha) and signal transducing (beta, gamma, or zeta) subunits. For Fc gamma RIIIa and Fc epsilon RI, association with the FcR gamma-chain is essential for surface ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae47a8139bfed385f0fdcedc8f30cbea
https://doi.org/10.1182/blood.v87.9.3593.bloodjournal8793593
https://doi.org/10.1182/blood.v87.9.3593.bloodjournal8793593
Autor:
John F. Morris, Jwm Hoppener, Frans M. A. Hofhuis, E. J. M. De Koning, Peter J.A. Capel, A Clark, J. S. Verbeek, E R Morris, G Posthuma
Publikováno v:
Proceedings of the National Academy of Sciences. 91:8467-8471
Islet amyloid polypeptide (IAPP) is the constituent peptide of amyloid deposits found in the islets of non-insulin-dependent diabetic patients. Formation of islet amyloid is associated with a progressive destruction of insulin-producing beta cells. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedcbf147d6e7bf10db0f4b5e3fbc49c
https://doi.org/10.1073/pnas.91.18.8467
https://doi.org/10.1073/pnas.91.18.8467
Human Islet Amyloid Polypeptide Accumulates at Similar Sites in Islets of Transgenic Mice and Humans
Autor:
K. L. Van Hulst, C. Oosterwijk, Jwm Hoppener, J. S. Verbeek, John F. Morris, A Clark, E. J. P. de Koning, C. A. Baker, Cornelis J.M. Lips
Publikováno v:
Diabetes. 43:640-644
The cellular mechanisms responsible for conversion of islet amyloid polypeptide (IAPP) into insoluble amyloid deposits in non-insulin-dependent diabetes mellitus (NIDDM) are not clear. Overexpression of IAPP and the amino acid sequence of human IAPP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5965526cbe2ae8184ef3229a2d01b02b
https://doi.org/10.2337/diab.43.5.640
https://doi.org/10.2337/diab.43.5.640
Autor:
H.S. Jansz, A Clark, Cornelis J.M. Lips, Jwm Hoppener, K. L. Van Hulst, E.J.P. de Koning, C. Oosterwijk, J. S. Verbeek, Peter J.A. Capel
Publikováno v:
Journal of Cellular Biochemistry. 55:39-53
Islet amyloid polypeptide ("amylin") is the major protein component of amyloid deposits in pancreatic islets of type 2 (non-insulin-dependent) diabetic patients. Islet amyloid polypeptide consists of 37 amino acids, is co-produced and co-secreted wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd677e38136676476b05d202098ce90
https://doi.org/10.1002/jcb.240550006
https://doi.org/10.1002/jcb.240550006
Autor:
E. J. P. de Koning, Frans M. A. Hofhuis, S. van Gaalen, Cornelis J.M. Lips, K. L. Van Hulst, John F. Morris, A Clark, Jwm Hoppener, W. H. L. Hackeng, M. J. H. Berends, Peter J.A. Capel, H. J. Visser-Vernooy, C. Oosterwijk, H.S. Jansz, J. S. Verbeek
Publikováno v:
Diabetologia. 36:1258-1265
Type 2 (non-insulin-dependent) diabetes mellitus is characterised by hyperglycaemia, peripheral insulin resistance, impaired insulin secretion and pancreatic islet amyloid formation. The major constituent of islet amyloid is islet amyloid polypeptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f9ca006906d196e17aa66ca17bf42e
https://doi.org/10.1007/bf00400803
https://doi.org/10.1007/bf00400803
Autor:
M van Vugt, Takashi Saito, H.H van Ojik, Shozo Izui, Sandra M. M. Hellwig, G-J B van Ommen, Lucien A. Aarden, J. Gerber, R. Roozendaal, W.B. van den Berg, David M. Mosser, S.A da Silveira, S. de Kimpe, Andreea Ioan-Facsinay, Y.F de Jong, Christine Sedlik, Frans M. A. Hofhuis, J.G.J. van de Winkel, J. S. Verbeek, Sebastian Amigorena, P.L.E.M. van Lent
Publikováno v:
Immunity, 16, 391-402
Immunity, Vol. 16, No 3 (2002) pp. 391-402
Immunity, 16(3), 391-402. Cell Press
Immunity, 16, 3, pp. 391-402
Immunity, Vol. 16, No 3 (2002) pp. 391-402
Immunity, 16(3), 391-402. Cell Press
Immunity, 16, 3, pp. 391-402
Item does not contain fulltext The high-affinity receptor for IgG, FcgammaRI, shares its capacity to bind IgG2a immune complexes (IgG2a-IC) with the low-affinity receptor FcgammaRIII and complement factors, hampering the definition of its biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a3cae053f3ff12d83428dcebf70697
http://hdl.handle.net/2066/142819
http://hdl.handle.net/2066/142819