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Tocopherol analogs suppress arachidonic acid metabolism via phospholipase inhibition

Autor: Luciann L. Hruza, S. C. Jacobs, J S Hebert, Alice P. Pentland, Aubrey R. Morrison, L Packer

Publikováno v: Journal of Biological Chemistry. 267:15578-15584

alpha-Tocopherol and three derivatives in which the phytol chain is modified or deleted were examined for their effect on cultured keratinocyte arachidonic acid metabolism. 2,2,5,7,8-Pentamethyl-6-hydroxychromane (PMC), in which the phytol chain is r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0fa288e7a441f63f65e3365129dab34c
https://doi.org/10.1016/s0021-9258(19)49575-6

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Enhanced prostaglandin synthesis after ultraviolet-B exposure modulates DNA synthesis of lens epithelial cells and lowers intraocular pressure in vivo

Autor: U P, Andley, B, Becker, J S, Hebert, J R, Reddan, A R, Morrison, A P, Pentland

Publikováno v: Investigative ophthalmologyvisual science. 37(1)

To study the functional significance of prostaglandin synthesis after ultraviolet-B (UVB) exposure of cultured human lens epithelial cells and rabbit eyes in vivo.Prostaglandin E2 (PGE2) was assayed using a radioimmunoassay (RIA) and mass spectroscop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ec4eb327e5a77e2a268455faae1e3ad8
https://pubmed.ncbi.nlm.nih.gov/8550317

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Modulation of lens epithelial cell proliferation by enhanced prostaglandin synthesis after UVB exposure

Autor: U P, Andley, J S, Hebert, A R, Morrison, J R, Reddan, A P, Pentland

Publikováno v: Investigative ophthalmologyvisual science. 35(2)

The goals of this investigation were to examine the synthesis of prostaglandins after UVB exposure of lens epithelial cells and to investigate their role in cell proliferation.Cultured rabbit lens epithelial cells (cell line N/N1003A) were exposed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::419e2b0685dd7702c249487d18b03f79
https://pubmed.ncbi.nlm.nih.gov/8112984

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Tocopherol analogs suppress arachidonic acid metabolism via phospholipase inhibition

Autor: A P, Pentland, A R, Morrison, S C, Jacobs, L L, Hruza, J S, Hebert, L, Packer

Publikováno v: The Journal of biological chemistry. 267(22)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::771b717562f4c85e9e4767e4aa34292d
https://pubmed.ncbi.nlm.nih.gov/1639798

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