Zobrazeno 1 - 10
of 41
pro vyhledávání: '"J S, Fink"'
Autor:
J S Fink, Aviva J. Symes
Publikováno v:
Proinflammatory and Antiinflammatory Peptides ISBN: 9781003064695
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::489af1e5a8e543faf70c204cfd4d3058
https://doi.org/10.1201/9781003064695-15
https://doi.org/10.1201/9781003064695-15
Publikováno v:
Journal of Neurochemistry. 66:362-368
The actions of the neurotransmitter adenosine are mediated by a family of high-affinity, G protein-coupled receptors. We have characterized the gene for the human A2a subtype of adenosine receptor (hA2aR) and determined levels of A2aR mRNA in human b
Autor:
Vincent J. Aloyo, Yuehang Xu, Rosario Moratalla, Timothy J. Turner, Jing Chen, Mark A. Beilstein, David G. Standaert, Michael A. Schwarzschild, J. S. Fink
Publikováno v:
Neuroscience. 97:195-204
A 2A adenosine receptors are highly expressed in the striatum where they modulate dopaminergic activity. The role of A 2A receptors in psychostimulant action is less well understood because of the lack of A 2A -selective compounds with access to the
A2AAdenosine Receptor Deficiency Attenuates Brain Injury Induced by Transient Focal Ischemia in Mice
Autor:
Rosario Moratalla, Michael A. Schwarzschild, J. S. Fink, Michael A. Moskowitz, David G. Standaert, Jing Chen, Zhihong Huang, Jianya Ma, Jinmin Zhu
Publikováno v:
The Journal of Neuroscience. 19:9192-9200
Extracellular adenosine critically modulates ischemic brain injury, at least in part through activation of the A1adenosine receptor. However, the role played by the A2Areceptor has been obscured by intrinsic limitations of A2Aadenosinergic agents. To
Publikováno v:
Journal of Biological Chemistry. 273:6233-6241
The src homology 2 (SH2) domain-containing protein-tyrosine phosphatase SHP-2 has been implicated as an important positive regulator of several mitogenic signaling pathways. SHP-2 has more recently been shown to be tyrosine phosphorylated and recruit
Publikováno v:
European Journal of Pharmacology. 336:71-80
Protein kinase C regulates mRNAs encoding several G protein-linked receptors but its role in adenosine A2a receptor expression is not known. We tested the hypothesis that protein kinase C activated by tetradecanoyl phorbol acetate (TPA) regulates ade
STAT proteins are activated by ciliary neurotrophic factor in cells of central nervous system origin
Publikováno v:
Journal of Neuroscience Research. 43:403-411
Neuropoietic cytokines, including ciliary neurotrophic factor (CNTF) and leukemia inhibitory factor (LIF), have survival effects on cells of the peripheral and central nervous systems (PNS and CNS). CNTF and LIF also produce differentiation in some c
Publikováno v:
Anesthesia & Analgesia. 81:1181-1185
The actions of dopamine are mediated by specific, high-affinity, G protein-coupled receptors. Multiple subtypes of dopamine receptors have been characterized, including the D2 subtype (D2R). Cells within the dorsal root and petrosal ganglia of the ra
Publikováno v:
NeuroReport. 6:2240-2244
Leukemia inhibitory factor (LIF) is a member of a family of neuropoietic cytokines which influence neuronal survival, differentiation and response to injury. In cell lines LIF activates the Jak/Tyk tyrosine kinases and the STAT family of transcriptio
Autor:
J. S. Fink, J. H. Growdon, W. Koller, C. W. Olanow, J. B. Bennett, Roger Kurlan, Christopher G. Goetz, P. LeWitt, O. Suchowersky, G. Paulson, K. Shannon, G. F. Wooten, A. H. Rajput, Joseph H. Friedman, S. Gancher, M. F. Brin, J. Nutt, Robert L. Rodnitzky, C. Tanner
Publikováno v:
New England Journal of Medicine. 328:176-183
In 1987 we began a multicenter controlled clinical trial of deprenyl (a monoamine oxidase inhibitor) and tocopherol (a component of vitamin E that traps free radicals) in the treatment of early Parkinson's disease. We randomly assigned 800 patients t