Zobrazeno 1 - 3
of 3
pro vyhledávání: '"J S, DeFrank"'
Publikováno v:
The Journal of biological chemistry. 274(19)
scid mouse embryonic fibroblasts are deficient in DNA-dependent protein kinase activity due to a mutation in the C-terminal domain of the catalytic subunit (DNA-PKcs). When exposed to ionizing radiation, the increase in levels of p53 was the same as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7b1a56e287c8313a7caa2a0d8974c49
https://pubmed.ncbi.nlm.nih.gov/10224064
https://pubmed.ncbi.nlm.nih.gov/10224064
Publikováno v:
Cancer research. 56(23)
We have shown previously that p53(-/-) fibroblasts show greater sensitization by caffeine to the lethal effects of ionizing radiation compared with p53(+/+) cells. Recently published data have suggested a possible role of p53 in nucleotide excision r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a583a616d3be2d0f488ada44153ac1e
https://pubmed.ncbi.nlm.nih.gov/9393772
https://pubmed.ncbi.nlm.nih.gov/9393772
Autor:
S N, Powell, J S, DeFrank, P, Connell, M, Eogan, F, Preffer, D, Dombkowski, W, Tang, S, Friend
Publikováno v:
Cancer research. 55(8)
Most drug discovery efforts have focused on finding new DNA-damaging agents to kill tumor cells preferentially. An alternative approach is to find ways to increase tumor-specific killing by modifying tumor-specific responses to that damage. In this r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::940e66d36d898a7fdbcec0be4b2f9316
https://pubmed.ncbi.nlm.nih.gov/7712468
https://pubmed.ncbi.nlm.nih.gov/7712468