Zobrazeno 1 - 10
of 53
pro vyhledávání: '"J S, Bromberg"'
Publikováno v:
The Journal of Immunology. 157:1863-1869
CD2 is a T cell surface glycoprotein that mediates both cell-cell adhesion and transmembrane signal transduction. To construct a model for the in vivo evaluation of human (h)CD2 function and hCD2-related reagents, hCD2 transgenic mice and murine (m)C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffad658f1f98f87de521a94f6046b095
https://doi.org/10.4049/jimmunol.157.5.1863
https://doi.org/10.4049/jimmunol.157.5.1863
Autor:
L Qin, K D Chavin, Y Ding, H Tahara, J P Favaro, J E Woodward, T Suzuki, P D Robbins, M T Lotze, J S Bromberg
Publikováno v:
The Journal of Immunology. 156:2316-2323
A murine heterotopic, nonvascularized cardiac allograft model was used to examine the effects of the immunosuppressive cytokine, viral IL-10 (vIL-10), delivered by gene transfer on graft rejection. Retroviral-mediated gene transfer and expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cf03e364f6ef798692dfa27a76dea74
https://doi.org/10.4049/jimmunol.156.6.2316
https://doi.org/10.4049/jimmunol.156.6.2316
Publikováno v:
Transplantation. 59:1162-1170
Anti-CD2 mAbs suppress T cell immunity and prolong allograft survival in vivo while inducing the down-modulation of CD2 expression. Manipulation of cell surface molecules may be important in inducing tolerance, so down-modulation of CD2 expression on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa066d238420f845ed299d3d274ea5f
https://doi.org/10.1097/00007890-199504270-00015
https://doi.org/10.1097/00007890-199504270-00015
Publikováno v:
The Journal of Immunology. 152:3729-3739
The mechanism by which anti-CD2 mAbs inhibit hapten-specific and alloantigen specific CTL was explored. In vivo administration of alpha-CD2 mAbs resulted in 80 to 100% inhibition of alloantigen specific CTLs. Mixing cells from control animals with ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c75540b74c14f5962fe1fa5525dfeb7d
https://doi.org/10.4049/jimmunol.152.8.3729
https://doi.org/10.4049/jimmunol.152.8.3729
Publikováno v:
The Journal of Immunology. 151:7249-7259
Administration of mAb against either the CD2 or CD3 receptor prolongs graft survival in CBA recipients in a heterotopic, nonvascularized cardiac transplant model, whereas the combination of mAb produces indefinite survival. Combined alpha-CD2 plus al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c7314654f0a6daf638fe08be7af3290
https://doi.org/10.4049/jimmunol.151.12.7249
https://doi.org/10.4049/jimmunol.151.12.7249
Publikováno v:
The Journal of Immunology. 148:3412-3417
Rabbit anti-murine TNF-alpha antibodies were administered in vivo to mice to evaluate the role of TNF-alpha in T cell-mediated immunity. Anti-TNF suppressed the in vivo development of contact sensitivity to the hapten TNP in a dose-dependent fashion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8df14edcb5e5608e631a03480f54c4d
https://doi.org/10.4049/jimmunol.148.11.3412
https://doi.org/10.4049/jimmunol.148.11.3412
Publikováno v:
Methods in enzymology. 346
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::444100ce82610a0426ed5160b6c9ad9d
https://pubmed.ncbi.nlm.nih.gov/11883069
https://pubmed.ncbi.nlm.nih.gov/11883069
Publikováno v:
Transplantation. 69(1)
Decapeptides derived from human HLA class I sequences have been shown to prolong allograft survival. The mechanism of action of these peptides has been uncertain, because they act in an MHC unrestricted manner. Recently, it was found that these pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebf9ab690dc6e8973ef46e11df912870
https://pubmed.ncbi.nlm.nih.gov/10653390
https://pubmed.ncbi.nlm.nih.gov/10653390
Autor:
C V, Paya, J J, Fung, M A, Nalesnik, E, Kieff, M, Green, G, Gores, T M, Habermann, P H, Wiesner, J L, Swinnen, E S, Woodle, J S, Bromberg
Publikováno v:
Transplantation. 68(10)
Epstein-Barr virus-induced posttransplant lymphoproliferative disease (EBV-PTLD) continues to be a major complication after solid organ transplantation in high-risk patients. Despite the identification of risk factors that predispose patients to deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4a3b42676a924c7e149e3e41438ac8b
https://pubmed.ncbi.nlm.nih.gov/10589949
https://pubmed.ncbi.nlm.nih.gov/10589949
Publikováno v:
Transplantation. 67(5)
Antigen specific allograft tolerance is induced in mice by anti-CD2 plus anti-CD3epsilon monoclonal antibody (mAb) treatment. Because anti-CD2 mAb inhibits several aspects of anti-CD3epsilon driven T cell activation, we investigated what components o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e3d58ea3ab9a40d5bab78bf11ee47e6
https://pubmed.ncbi.nlm.nih.gov/10096532
https://pubmed.ncbi.nlm.nih.gov/10096532