Zobrazeno 1 - 10
of 10
pro vyhledávání: '"J S, Babischkin"'
Publikováno v:
Biology of reproduction. 65(4)
The present study was conducted to determine the developmental expression of placental insulin-like growth factor (IGF)-II, IGF-binding protein (IGFBP)-1 and -2, and IGF-II receptor mRNA expression during baboon pregnancy and whether estrogen, the le
Publikováno v:
Endocrinology. 140(12)
We have previously shown that estrogen regulates the development and function of the fetal and definitive/transitional zones of the primate fetal adrenal gland. Thus, during baboon pregnancy estrogen acts directly on the fetal zone to suppress ACTH-s
Publikováno v:
Endocrinology. 138(4)
We have previously shown a decrease in fetal zone-specific ACTH-stimulable dehydroepiandrosterone formation and an increase in definitive zone-specific cortisol biosynthesis in the baboon fetal adrenal gland in the second half of gestation. Therefore
Publikováno v:
Biology of reproduction. 56(1)
The present study determined whether estrogen has a role in regulating the P450 cholesterol side-chain cleavage enzyme (P450scc) and/or de novo/deesterification cholesterol pathways involved in progesterone biosynthesis within human syncytiotrophobla
Publikováno v:
Endocrinology. 138(1)
The present study was conducted to determine whether estrogen regulates the P-450 cholesterol side-chain cleavage (P-450scc) enzyme component of the progesterone biosynthetic pathway in the placenta during the second half of baboon pregnancy. Placent
Publikováno v:
Endocrinology. 137(12)
Cortisol-cortisone interconversion is catalyzed by the NADP/NADPH-dependent oxido-reductase, 11beta-hydroxysteroid dehydrogenase-1 (11betaHSD-1) and the NAD-dependent oxidase, 11betaHSD-2. Because of the importance of placental corticosteroid metabol
Publikováno v:
Journal of Biological Chemistry. 261:8589-8592
Insulin is known to increase the de novo synthesis of inositol phospholipids in rat epididymal fat pads. We presently examined the effects of insulin on the hydrolysis of inositol phospholipids in this tissue. Relatively small (30-40%) but significan
Autor:
J. S. Babischkin, Mary L. Standaert, N K Rosic, Robert V. Farese, Denise R. Cooper, R J Pollet, John S. Davis
Publikováno v:
Diabetes. 35(9)
We have previously suggested that insulin effects on 2-deoxyglucose (2-DOG) uptake in BC3H-1 myocytes are due to increases in de novo phospholipid synthesis, diacylglycerol generation, and protein kinase C activation. To test this hypothesis further,
Autor:
Demeteria E. Barnes, N K Rosic, Mary L. Standaert, J. S. Babischkin, R J Pollet, R Hock, John S. Davis, Robert V. Farese
Publikováno v:
The Biochemical journal. 231(2)
We have previously reported that insulin increases the synthesis de novo of phosphatidic acid (PA), phosphatidylinositol (PI), phosphatidylinositol 4-phosphate (PIP), phosphatidylinositol 4,5-bisphosphate (PIP2) and diacylglycerol (DAG) in BC3H-1 myo
Publikováno v:
The Journal of biological chemistry. 261(19)
Insulin is known to increase the de novo synthesis of inositol phospholipids in rat epididymal fat pads. We presently examined the effects of insulin on the hydrolysis of inositol phospholipids in this tissue. Relatively small (30-40%) but significan