Zobrazeno 1 - 10
of 103
pro vyhledávání: '"J Rozen"'
Publikováno v:
Life, Vol 14, Iss 10, p 1260 (2024)
Neuroblastoma is a devastating disease accounting for ~15% of all childhood cancer deaths. Collagen content and fiber association within the tumor stroma influence tumor progression and metastasis. High expression levels of collagen receptor kinase,
Externí odkaz:
https://doaj.org/article/42150715b82c480aaa280990478245ca
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-20 (2023)
Abstract Background RUNX1 is a transcription factor and a master regulator for the specification of the hematopoietic lineage during embryogenesis and postnatal megakaryopoiesis. Mutations and rearrangements on RUNX1 are key drivers of hematological
Externí odkaz:
https://doaj.org/article/94be87776c5746f7bbd9ec462489c35e
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 197 (2024)
High-risk neuroblastoma is a very aggressive pediatric cancer, accounting for ~15% of childhood cancer mortality. Therefore, novel therapeutic strategies for the treatment of neuroblastoma are urgently sought. Here, we focused on the potential implic
Externí odkaz:
https://doaj.org/article/0ee963b66a144d33ba4c76f4b0b2dd62
Autor:
Lei Huang, Xiao-Ou Zhang, Esteban J. Rozen, Xiaomei Sun, Benjamin Sallis, Odette Verdejo-Torres, Kim Wigglesworth, Daniel Moon, Tingting Huang, John P. Cavaretta, Gang Wang, Lei Zhang, Jason M. Shohet, Mary M. Lee, Qiong Wu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
‘Protein arginine methyltransferase 5 (PRMT5) is known to regulate the expression of genes involved in metastasis. Here, the authors show that PRMT5 methylates Akt and methylation is required for phosphorylation and activation of Akt; ultimately le
Externí odkaz:
https://doaj.org/article/08beede925d14353979613ff4f723b89
Autor:
Esteban J. Rozen, Julia Roewenstrunk, María José Barallobre, Chiara Di Vona, Carole Jung, Ana F. Figueiredo, Jeroni Luna, Cristina Fillat, Maria L. Arbonés, Mariona Graupera, Miguel A. Valverde, Susana de la Luna
Publikováno v:
Cell Reports, Vol 23, Iss 6, Pp 1867-1878 (2018)
Summary: Angiogenesis is a highly regulated process essential for organ development and maintenance, and its deregulation contributes to inflammation, cardiac disorders, and cancer. The Ca2+/nuclear factor of activated T cells (NFAT) signaling pathwa
Externí odkaz:
https://doaj.org/article/91b2dfb0e22745f7bf0a389f39323eb3
Autor:
R. Bao, C. Durfee, J. Zhang, L. Qin, J. Rozen, H. Zhou, J. Li, S. Mukesh, S. Pancharatnam, K. Zhao, C. D. Adams, E. Leobandung, V. Narayanan, D. Guo, H. Bu
Publikováno v:
2021 IEEE International Electron Devices Meeting (IEDM).
Autor:
Lei Huang, Xiao-Ou Zhang, Esteban J. Rozen, Xiaomei Sun, Benjamin Sallis, Odette Verdejo-Torres, Kim Wigglesworth, Daniel Moon, Tingting Huang, John P. Cavaretta, Gang Wang, Lei Zhang, Jason M. Shohet, Mary M. Lee, Qiong Wu
Publikováno v:
Nature communications. 13(1)
Protein arginine methyltransferase 5 (PRMT5) is the primary methyltransferase generating symmetric-dimethyl-arginine marks on histone and non-histone proteins. PRMT5 dysregulation is implicated in multiple oncogenic processes. Here, we report that PR
Autor:
J. Rozen, Y. Ogawa, M. Hatanaka, T. Ando, E. Cartier, M.M. Frank, M. Hopstaken, J. Bruley, K.-T. Lee, J.-B. Yau, Y. Sun, R.L. Bruce, C. D'Emic, X. Sun, K. Suu, R.T. Mo, E. Leobandung, V. Narayanan
Publikováno v:
Extended Abstracts of the 2018 International Conference on Solid State Devices and Materials.
Autor:
X. Sun, C. D'Emic, C.-W. Cheng, A. Majumdar, Y. Sun, E. Cartier, R. L. Bruce, M. Frank, H. Miyazoe, K.-T. Shiu, S. Lee, J. Rozen, J. Patel, T. Ando, W.-B. Song, M. Lofaro, M. Krishnan, B. Obrodovic, K.-T. Lee, H. Tsai, W.-E. Wang, W. Spratt, K. Chan, J.-B. Yau, P. Hashemi, M. Khojasteh, M. Cantoro, J. Ott, T. Rakshit, Y. Zhu, D. Sadana, C.-C. Yeh, V. Narayanan, R. T. Mo, Y.-C. Heo, D.-W. Kim, M. S. Rodder, E. Leobandung
Publikováno v:
2017 Symposium on VLSI Technology.
We report the fabrication of short-channel FinFETs on InGaAs-on-silicon wafers using the aspect ratio trapping (ART) technique. We demonstrate excellent short-channel control down to 20 nm gate length due to scaled fin width down to 9 nm and reductio
Publikováno v:
International Journal of Thermal Sciences. 49:1561-1566
Several transport models are investigated in the context of two-dimensional fiber composites. We compare the thermal and electrical transport through the fiber composites as a function of the conductivity ratio and the fiber density. Three models wil