Zobrazeno 1 - 10
of 27
pro vyhledávání: '"J Ronald, Doucette"'
Publikováno v:
Neuromethods ISBN: 9781071604267
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ab5bed7370e9b6176779f4f8e3742fd
https://doi.org/10.1007/978-1-0716-0428-1_15
https://doi.org/10.1007/978-1-0716-0428-1_15
Autor:
Shaoping Ji, Kendra L Furber, LaRhonda Sobchishin, Adil J. Nazarali, Merlin P. Thangaraj, Jotham K. Gan, J. Ronald Doucette
Publikováno v:
Journal of Biological Chemistry. 292:5166-5182
Myelination is controlled by timely expression of genes involved in the differentiation of oligodendrocyte precursor cells (OPCs) into myelinating oligodendrocytes (OLs). Sirtuin 2 (SIRT2), a NAD+-dependent deacetylase, plays a critical role in OL di
Autor:
Adil J. Nazarali, Merlin P. Thangaraj, J. Ronald Doucette, Kendra L Furber, Shaoping Ji, LaRhonda Sobchishin
Publikováno v:
Cellular and molecular neurobiology. 38(1)
Sirtuin2 (SIRT2) is a deacetylase enzyme predominantly expressed in myelinating glia of the central nervous system (CNS). We have previously demonstrated that Sirt2 expression enhances oligodendrocyte (OL) differentiation and arborization in vitro, b
Autor:
Merlin P, Thangaraj, Kendra L, Furber, Jotham K, Gan, Shaoping, Ji, Larhonda, Sobchishin, J Ronald, Doucette, Adil J, Nazarali
Publikováno v:
The Journal of biological chemistry. 292(13)
Myelination is controlled by timely expression of genes involved in the differentiation of oligodendrocyte precursor cells (OPCs) into myelinating oligodendrocytes (OLs). Sirtuin 2 (SIRT2), a NAD+-dependent deacetylase, plays a critical role in OL di
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1436
SIRT2 is a NAD(+)-dependent deacetylase that belongs to the sirtuin family, which is comprised of seven members (SIRT1-SIRT7) in humans. Furthermore, recent study shows that the Sirt2 gene has three transcript variants in mice. Several diverse protei
Publikováno v:
Methods in Molecular Biology ISBN: 9781493936656
SIRT2 is a NAD(+)-dependent deacetylase that belongs to the sirtuin family, which is comprised of seven members (SIRT1-SIRT7) in humans. Furthermore, recent study shows that the Sirt2 gene has three transcript variants in mice. Several diverse protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088e7cd940c3f86cf10c4fe12a2262c9
https://doi.org/10.1007/978-1-4939-3667-0_13
https://doi.org/10.1007/978-1-4939-3667-0_13
Publikováno v:
Journal of Molecular Cell Biology. 3:351-359
Although Sirt2 is primarily expressed in oligodendrocytes of the central nervous system, its role in oligodendroglial lineage differentiation is not fully understood. Our findings demonstrate that the transcription factor Nkx2.2 binds to the Sirt2 pr
Publikováno v:
Cellular and Molecular Neurobiology. 30:607-629
During aging, there is a decrease both in the stability of central nervous system (CNS) myelin once formed and in the efficiency of its repair by oligodendrocytes (OLs). To study CNS remyelination during aging, we used the cuprizone (a copper chelato
Publikováno v:
Glia. 55:1287-1299
Oligodendrocytes (OGs) assemble the myelin sheath around axons in the central nervous system. Specification of cells into the OG lineage is largely the result of interplay between bone morphogenetic protein, sonic hedgehog and Notch signaling pathway
Publikováno v:
Cellular and Molecular Neurobiology. 26:801-819
1. The olfactory epithelium (OE) is a simple structure that gives rise to olfactory sensory neurons (OSNs) throughout life. 2. Numerous transcription factors (TFs) are expressed in regions of the OE which contain progenitor cells and OSNs. The functi