Zobrazeno 1 - 10
of 20
pro vyhledávání: '"J Robert Bostwick"'
Autor:
Brandon J. Metge, Heba Allah M. Alsheikh, Sarah C. Kammerud, Dongquan Chen, Devika Das, N. Miranda Nebane, J. Robert Bostwick, Lalita A. Shevde, Rajeev S. Samant
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-14 (2024)
Abstract Metastatic dissemination from the primary tumor is a complex process that requires crosstalk between tumor cells and the surrounding milieu and involves the interplay between numerous cellular-signaling programs. Epithelial–mesenchymal tra
Externí odkaz:
https://doaj.org/article/fdb5e2dddfe24017af39bdd3f65354a8
Autor:
Lynn Rasmussen, Shalisa Sanders, Melinda Sosa, Sara McKellip, N. Miranda Nebane, Yohanka Martinez-Gzegozewska, Andrew Reece, Pedro Ruiz, Anna Manuvakhova, Ling Zhai, Brooke Warren, Aliyah Curry, Qinghua Zeng, J. Robert Bostwick, Paige N. Vinson
Publikováno v:
SLAS Discovery, Vol 29, Iss 5, Pp 100160- (2024)
Four years after the beginning of the COVID-19 pandemic, it is important to reflect on the events that have occurred during that time and the knowledge that has been gained. The response to the pandemic was rapid and highly resourced; it was also bui
Externí odkaz:
https://doaj.org/article/6dbac02830044c3ab9f63c4c7d35bd4c
Autor:
Jonathan R Roth, Travis Rush, Derian A Pugh, Hunter B Dean, J. Nicholas Cochran, Samantha J Thompson, Adam R Aldaher, Jacob S Mesina, Pedro Ruiz, Vibha Pathak, Mousheng Wu, J Robert Bostwick, Mark J Suto, Corinne E Augelli‐Szafran, Erik D. Roberson
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2af62a76b07b7701eec12b82a4e6067
https://doi.org/10.1002/alz.055501
https://doi.org/10.1002/alz.055501
Autor:
Josh Echols, Ming Du, David M. Bedwell, Lynn Rasmussen, Mark J. Suto, Amna Siddiqui, J. Robert Bostwick, Kim M. Keeling, Halil Dündar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2640c9f9d8e128fa897a8180c7b4037
https://avesis.gazi.edu.tr/publication/details/c93d3982-ff9e-443f-9cf0-af1c21a5f74c/oai
https://avesis.gazi.edu.tr/publication/details/c93d3982-ff9e-443f-9cf0-af1c21a5f74c/oai
Autor:
Leah McAleer, Ling Zhai, Maarten E. A. Reith, J. Robert Bostwick, Eunie Cho, Shea McDowell, Guangyan Zhou, Robert R. Luedtke, Subramaniam Ananthan, Judith V. Hobrath, Tamara Antonio, Michelle Taylor, Surendra K. Saini, Indira Padmalayam
Publikováno v:
Journal of Medicinal Chemistry
Antagonist and partial agonist modulators of the dopamine D3 receptor (D3R) have emerged as promising therapeutics for the treatment of substance abuse and neuropsychiatric disorders. However, development of druglike lead compounds with selectivity f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d96e1022ff66e6fd23d384fb64dafab
https://doi.org/10.1021/jm500801r
https://doi.org/10.1021/jm500801r
Autor:
Xiaojiao Xue, David M. Bedwell, Bo Liu, Kim M. Keeling, Martin Mense, Feng Liang, Emily Falk Libby, Marina Mazur, J. Robert Bostwick, Mark J. Suto, Haibo Shang, E. Lucile White, Venkateshwar Mutyam, Ming Du, Jeong S. Hong, Steven M. Rowe, Lynn Rasmussen
Publikováno v:
American journal of respiratory and critical care medicine. 194(9)
Premature termination codons (PTCs) in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause cystic fibrosis (CF). Several agents are known to suppress PTCs but are poorly efficacious or toxic.To determine whether there are clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b85c84689bbd73f1a99b916f360668
https://pubmed.ncbi.nlm.nih.gov/27797609
https://pubmed.ncbi.nlm.nih.gov/27797609
Autor:
Vipa Ravyn, J. Robert Bostwick
Publikováno v:
Journal of Receptors and Signal Transduction. 26:241-258
A recently identified novel Galphaolf variant, XLGalphaolf, is shown to functionally couple to the human adenosine A2A receptor (A2AR). In Sf9 cells expressing A2AR, beta1, and gamma2, co-expression of XLGalphaolf increased NECA-induced [35S]GTPgamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d3700a0faa44703fcf62a69b9f452eb
https://doi.org/10.1080/10799890600710592
https://doi.org/10.1080/10799890600710592
Publikováno v:
Journal of Neurochemistry. 59:236-244
Dissociated rat septal nucleus cells cultured in defined medium exhibited twofold increases in the maximal rates of sodium-dependent, high-affinity choline uptake and acetylcholine formation when grown in the presence of phosphoethanolamine. The effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bc7271b7ebf73d52d1d52cedae4419
https://doi.org/10.1111/j.1471-4159.1992.tb08896.x
https://doi.org/10.1111/j.1471-4159.1992.tb08896.x
Autor:
J. Robert Bostwick, Weidong Le
Publikováno v:
Analytical Biochemistry. 192:125-130
A radiometric assay for tyrosine hydroxylase employing a coupled nonenzymatic decarboxylation of L-[14C]Dopa formed from L-[14C]tyrosine has been adapted for performance in a 96 microwell culture plate. The method uses an easily manufactured plate ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5061e4f4880e9d24fcbfe6b984a7fb3
https://doi.org/10.1016/0003-2697(91)90196-z
https://doi.org/10.1016/0003-2697(91)90196-z
Publikováno v:
Developmental Brain Research. 67:375-377
In this study we determined the temporal association between the appearance of the dopamine transporter, measured by 1-[2-(diphenylmethoxy)ethyl)]-4-(3-phenylpropyl)-piperazine ([3H]-GBR12935), a potent and selective inhibitor of dopamine uptake, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bdfc6a738dcccd62de6ff82fb195df
https://doi.org/10.1016/0165-3806(92)90238-r
https://doi.org/10.1016/0165-3806(92)90238-r