Zobrazeno 1 - 10
of 16
pro vyhledávání: '"J Richard Brewer"'
Autor:
Autumn G. York, Mathias H. Skadow, Rihao Qu, Joonseok Oh, Walter K. Mowel, J. Richard Brewer, Eleanna Kaffe, Kevin J. Williams, Yuval Kluger, Jason M. Crawford, Stephen T. Smale, Steven J. Bensinger, Richard A. Flavell
Publikováno v:
bioRxiv
Unchecked chronic inflammation is the underlying cause of many diseases, ranging from inflammatory bowel disease to obesity and neurodegeneration. Given the deleterious nature of unregulated inflammation, it is not surprising that cells have acquired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc43508e567e65fcce448ea1f93699a
https://doi.org/10.1101/2023.05.07.539780
https://doi.org/10.1101/2023.05.07.539780
Autor:
Ayan Ray, Catarina Catela, Pierre Mazot, Colin J. Dinsmore, J. Richard Brewer, Philippe Soriano
Publikováno v:
Genes & Development. 34:1735-1752
FGFs are key developmental regulators that engage a signal transduction cascade through receptor tyrosine kinases, prominently engaging ERK1/2 but also other pathways. However, it remains unknown whether all FGF activities depend on this canonical si
Autor:
Bing Su, Piotr Bielecki, George Kollias, Vassilis Aidinis, Richard M. Breyer, J Richard Brewer, Ana Henriques, Maren Bacher, Rihao Qu, Manolis Roulis, Jing Jiao, Niki Chalkidi, Dhanpat Jain, Harvey R. Herschman, Eleanna Kaffe, Xiaoyun Zhao, Aimilios Kaklamanos, Marlene S Knapp, Holly N. Blackburn, Jun Zhao, Marina Schernthanner, Richard A. Flavell, Laura-Sophie Frommelt, Vasiliki Koliaraki, Yuval Kluger
Publikováno v:
Nature. 580:524-529
The initiation of an intestinal tumour is a probabilistic process that depends on the competition between mutant and normal epithelial stem cells in crypts1. Intestinal stem cells are closely associated with a diverse but poorly characterized network
Autor:
Esen Sefik, Rihao Qu, Caroline Junqueira, Eleanna Kaffe, Haris Mirza, Jun Zhao, J. Richard Brewer, Ailin Han, Holly R. Steach, Benjamin Israelow, Holly N. Blackburn, Sofia Velazquez, Y. Grace Chen, Stephanie Halene, Akiko Iwasaki, Eric Meffre, Michel Nussenzweig, Judy Lieberman, Craig B. Wilen, Yuval Kluger, Richard A. Flavell
Publikováno v:
bioRxiv
Severe COVID-19 is characterized by persistent lung inflammation, inflammatory cytokine production, viral RNA, and sustained interferon (IFN) response all of which are recapitulated and required for pathology in the SARS-CoV-2 infected MISTRG6-hACE2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106c3ec8c6620543b3c1376ecd6d43ee
https://doi.org/10.1101/2021.09.27.461948
https://doi.org/10.1101/2021.09.27.461948
Autor:
Philippe Soriano, Pierre Mazot, Ayan Ray, J. Richard Brewer, Catarina Catela, Colin J. Dinsmore
Publikováno v:
Genes Dev
FGFs are key developmental regulators that engage a signal transduction cascade through receptor tyrosine kinases, prominently engaging ERK1/2 but also other pathways. However, it remains unknown whether all FGF activities depend on this canonical si
Publikováno v:
Nature Reviews Nephrology. 15:263-274
The recognition that intestinal microbiota exert profound effects on human health has led to major advances in our understanding of disease processes. Studies over the past 20 years have shown that host components, including components of the host im
Autor:
Mathias H. Skadow, Angel G. Solis, Abigail Jarret, J Richard Brewer, Alexandra Khitun, Holly R. Steach, Omair Khan, Will Bailis, Richard A. Flavell, Autumn G. York, Lina Kroehling, Ruaidhri Jackson, Christian C. D. Harman, Piotr Bielecki, Lelina Chang, Coco Duizer, Sarah A. Slavoff
Publikováno v:
Nature
The annotation of the mammalian protein coding genome is incomplete. Arbitrary open reading frame (ORF) size restriction and the absolute requirement for a methionine codon as the sole initiator of translation, have constrained identification of pote
Autor:
Colin J. Dinsmore, Philippe Soriano, Catarina Catela, Ayan Ray, J. Richard Brewer, Pierre Mazot
FGFs are key developmental regulators which engage a signal transduction cascade through receptor tyrosine kinases, typically involving ERK1/2, PI3K/AKT, and other effectors. However, it remains unknown if all FGF activities depend on kinase activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd90c60a6ae9d0bcfac5a191fa6e6e2a
https://doi.org/10.1101/2020.05.13.093252
https://doi.org/10.1101/2020.05.13.093252
Publikováno v:
Nature reviews. Nephrology. 15(5)
The recognition that intestinal microbiota exert profound effects on human health has led to major advances in our understanding of disease processes. Studies over the past 20 years have shown that host components, including components of the host im
Autor:
Manolis, Roulis, Aimilios, Kaklamanos, Marina, Schernthanner, Piotr, Bielecki, Jun, Zhao, Eleanna, Kaffe, Laura-Sophie, Frommelt, Rihao, Qu, Marlene S, Knapp, Ana, Henriques, Niki, Chalkidi, Vasiliki, Koliaraki, Jing, Jiao, J Richard, Brewer, Maren, Bacher, Holly N, Blackburn, Xiaoyun, Zhao, Richard M, Breyer, Vassilis, Aidinis, Dhanpat, Jain, Bing, Su, Harvey R, Herschman, Yuval, Kluger, George, Kollias, Richard A, Flavell
Publikováno v:
Cell Res
The initiation of an intestinal tumour is a probabilistic process that depends on the competition between mutant and normal epithelial stem cells in crypts