Zobrazeno 1 - 10
of 29
pro vyhledávání: '"J Ricardo McFaline-Figueroa"'
Autor:
Sebastian M. Christ, Gilbert Youssef, Shyam K. Tanguturi, Daniel Cagney, Diana Shi, J. Ricardo McFaline-Figueroa, Ugonma Chukwueke, Eudocia Q. Lee, Caroline Hertler, Nicolaus Andratschke, Michael Weller, David A. Reardon, Daphne Haas-Kogan, Matthias Guckenberger, Patrick Y. Wen, Rifaquat Rahman
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 44, Iss , Pp 100697- (2024)
Introduction and background: While recurrent glioblastoma patients are often treated with re-irradiation, there is limited data on the use of re-irradiation in the setting of bevacizumab (BEV), temozolomide (TMZ) re-challenge, or immune checkpoint in
Externí odkaz:
https://doaj.org/article/25491ed7bda84b609fc4d99318463fa8
Publikováno v:
Hematology/Oncology Clinics of North America. 36:133-146
Meningiomas are largely indolent tumors with a benign clinical course, but a minority exhibit aggressive behavior characterized by rapid growth, neurologic deficits, and increased mortality. Identifying high-risk patients requiring intervention is ch
Autor:
Fabio Iwamoto, Shyam Tanguturi, Arati Desai, Lakshmi Nayak, Erik Uhlmann, Tony Wang, Robert Lustig, Lauren Hertan, Stephen Bagley, Julia Hayden, Corey Laforest-Roys, Alona Muzikansky, Christine McCluskey, Ugonma Chukwueke, J Ricardo McFaline-Figueroa, Eudocia Lee, Patrick Y Wen, David Reardon
Publikováno v:
Neuro-Oncology. 24:vii63-vii64
Re-irradiation is therapeutically considered for select rGBM patients and may induce immunogenic cell death to stimulate anti-tumor immune responses. Our phase 2 study of re-irradiation with pembrolizumab among rGBM patients evaluated the efficacy an
Autor:
J Ricardo McFaline-Figueroa, Robert Prins, Yu Qiao, Lu Sun, Gang Li, Jiyoon Kim, Eudocia Lee, Lakshmi Nayak, Ugonma Chukwueke, Rameen Beroukhim, Tracy Batchelor, E Antonio Chiocca, Lisa Doherty, Jennifer Stefanik, Kathryn Partridge, Amanda Spearman, Maria Lavallee, Alexa Myers, Corey Laforest-Roys, Rachel Fox Garcia, Wenya Linda Bi, Omar Arnaout, Pierpaolo Peruzzi, G Rees Cosgrove, Keith Ligon, Isabel Arrillaga-Romany, Jennifer Clarke, David A Reardon, Timothy Cloughesy, Patrick Y Wen
Publikováno v:
Neuro-Oncology. 24:vii65-vii66
Glioblastoma is immunologically “cold”, with little clinical response to single-agent immune-checkpoint inhibitors (ICI). Our previous randomized study of neoadjuvant and adjuvant pembrolizumab versus adjuvant pembrolizumab in recurrent glioblast
Publikováno v:
Neurotherapeutics. 19:1689-1690
Autor:
Florence Coulet, Jill S. Barnholtz-Sloan, Marc Sanson, Adam Boynton, Aniket Shetty, Yvonne Y. Li, Tracy T. Batchelor, Marine Giry, Garrett M. Frampton, Alexandre Carpentier, Peter J. Park, Franck Bielle, Eudocia Q. Lee, Khê Hoang-Xuan, Jean-Yves Delattre, Leon Taquet, Philippe Cornu, Erell Guillerm, Andrew D. Cherniack, Liam F. Spurr, Robert E. Jones, Mehdi Touat, Rameen Beroukhim, Patrick Y. Wen, J. Bryan Iorgulescu, David Meredith, Kristine Pelton, Caroline Dehais, Radwa Sharaf, Sandro Santagata, Alex Duval, Kenin Qian, Nadia Younan, Florence Laigle-Donadey, Patricia Ho, J Ricardo McFaline-Figueroa, Juliana Bonardi, Mary Jane Lim-Fat, David A. Reardon, Capucine Baldini, Naomi Currimjee, Shakti H. Ramkissoon, Caroline Houillier, Katie Pricola Fehnel, Seth Malinowski, Dimitri Psimaras, Cristina Birzu, Charlotte Bellamy, Isidro Cortes-Ciriano, Keith L. Ligon, Jack Geduldig, Karima Mokhtari, Maite Verreault, Lee A. Albacker, Pratiti Bandopadhayay, Bertrand Mathon, Susan N. Chi, E. Antonio Chiocca, Agusti Alentorn, Dean Pavlick, Frank Dubois, Sangita Pal, Samy Ammari, Brian M. Alexander, Arnab Chakravarti, Azra H. Ligon, Sanda Alexandrescu, Ahmed Idbaih, Frédéric Beuvon, Lakshmi Nayak, Laurent Capelle, Aurélien Marabelle, Daphne A. Haas-Kogan, Raymond Y. Huang, Craig L. Bohrson, Wenya Linda Bi, Ruben Ferrer-Luna, Kin-Hoe Chow
Publikováno v:
Nature
A high tumour mutational burden (hypermutation) is observed in some gliomas1–5; however, the mechanisms by which hypermutation develops and whether it predicts the response to immunotherapy are poorly understood. Here we comprehensively analyse the
Autor:
Mary Jane Lim-Fat, Gilbert C Youssef, Mehdi Touat, J Bryan Iorgulescu, Sydney Whorral, Marie Allen, Rifaquat Rahman, Ugonma Chukwueke, J Ricardo McFaline-Figueroa, Lakshmi Nayak, Eudocia Q Lee, Tracy T Batchelor, Omar Arnaout, Pier Paolo Peruzzi, E Antonio Chiocca, David A Reardon, David Meredith, Sandro Santagata, Rameen Beroukhim, Wenya Linda Bi, Keith L Ligon, Patrick Y Wen
Publikováno v:
Neuro Oncol
Background Targeted gene NGS testing is available through many academic institutions and commercial entities and is increasingly incorporated in practice guidelines for glioblastoma (GBM). This single-center retrospective study aimed to evaluate the
Publikováno v:
Hematology/oncology clinics of North America. 36(1)
Meningiomas are largely indolent tumors with a benign clinical course, but a minority exhibit aggressive behavior characterized by rapid growth, neurologic deficits, and increased mortality. Identifying high-risk patients requiring intervention is ch
Autor:
Mary Jane Lim-Fat, Daniel N. Cagney, L. Nicolas Gonzalez Castro, David A. Reardon, Rifaquat Rahman, Omar Arnaout, Matthew N. DeSalvo, Christopher A. Potter, Eudocia Q. Lee, Gilbert Youssef, Wenya Linda Bi, J Ricardo McFaline-Figueroa, Timothy F. Cloughesy, Camden P. Bay, Jeffrey P. Guenette, Raymond Y. Huang, Patrick Y. Wen, Benjamin M. Ellingson
Publikováno v:
Neuro Oncol
BACKGROUND Accurate response criteria are crucial for determining treatment efficacy. The response assessment in neuro-oncology (RANO) criteria was developed to standardize response assessment in neuro-oncology. Modified RANO (m-RANO) criteria were r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a56ec641d76f21e84995c27ca2a94f
https://europepmc.org/articles/PMC8598494/
https://europepmc.org/articles/PMC8598494/
Autor:
Mary Jane Lim-Fat, Rifaquat Rahman, Bryan Iorgulescu, Varun Bhave, Gilbert Youssef, Marie Allen, Ugonma Chukwueke, J Ricardo McFaline-Figueroa, Lakshmi Nayak, Eudocia Lee, David A Reardon, Tracy Batchelor, Rameen Beroukhim, Raymond Huang, Wenya Linda Bi, Keith Ligon, Patrick Y Wen
Publikováno v:
Neuro-Oncology. 24:vii15-vii15
BACKGROUND Adverse events (AE) including seizures cause significant morbidity in patients with GBM. We propose a novel method for assessing genomic predictors of AEs using results from a clinical targeted sequencing platform with variant function ana