Zobrazeno 1 - 10
of 55
pro vyhledávání: '"J Rataud"'
Autor:
Warscotte, Jean-Marie Stutzmann, M. Lucas, Roger Demeure, Baudouin Maldague, Jean-Philippe Thiran, Isabelle Mottet, Jean-François Goudemant, J Rataud, Jean-Marie Maloteaux, F Wahl
Publikováno v:
Magma: Magnetic Resonance Materials in Physics, Biology, and Medicine. 5:185-191
The aim of this study was to investigate the effects of riluzole on the lesion induced by a permanent middle cerebral artery occlusion (MCAO) in rats. Riluzole at 4 or 8 mg/kg i.v. significantly reduced the cortical ischemic brain damage. With the mo
Autor:
Jeremy Pratt, Michel Reibaud, Florence Wahl, J. Rataud, E. Tecoult, Veronique Mary, Jean-Marie Stutzmann
Publikováno v:
CNS Drug Reviews. 3:83-101
Autor:
Jean-Claude Aloup, Jean-Marie Stutzmann, Michel Cheve, Michel Barreau, Francois Audiau, Alain Boireau, John Randle, Jacques Lavayre, Serge Mignani, J.‐C. Blanchard, Dominique Damour, Adam Doble, Gilles Dutruc-Rosset, J. Rataud, Patrick Jimonet, Andrees Bohme
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:2735-2740
Autor:
Jeremy Pratt, A. Doble, Serge Mignani, Jean-Charles Blanchard, Jacques Lavayre, J.-M. Stutzmann, Michel Barreau, O. Piot, J. Rataud, P.M. Laduron, Patrick Jimonet, C. Malgouris, Alain Boireau, Michel Reibaud
Publikováno v:
Bioorganic & Medicinal Chemistry. 2:793-798
RP 66055, a riluzole derivative, has been characterized as a potent anticonvulsant and in vivo neuroprotective agent.
Autor:
Gérard Ducrotoy, François Beaudoin, Serge Mignani, Dominique Lurier, Gilles Dutruc-Rosset, Jean-Marie Stutzmann, Michel Cheve, J. Rataud, Patrick Jimonet
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:983-988
Optical isomers of the riluzole derivative, sulfoxide RP 64406, were prepared in pure forms. No significant difference was found between the (+) and (−) isomers in their powerful antiglutamate activity.
Autor:
Dominique Damour, Francois Audiau, Adam Doble, Gilles Dutruc-Rosset, John Randle, Andrees Bohme, Jacques Lavayre, J. Rataud, J.‐C. Blanchard, Alain Boireau, Jean-Marie Stutzmann, Jean-Claude Aloup, Michel Cheve, Serge Mignani, Patrick Jimonet, Michel Barreau
Publikováno v:
ChemInform. 26
Autor:
Georg Andrees Bohme, Frédéric Darche, J. Rataud, Jean-Charles Blanchard, Jean-Marie Stutzmann, O. Piot
Publikováno v:
Brain Research. 548:315-317
The effects of systemic treatment with the CCK-B receptor antagonist L-365,260, its 3S-(-) enantiomer and the CCK-A receptor antagonist devazepide were assessed in the plus-maze procedure in mice. L-365,260 (1-1000 micrograms.kg-1 i.p.) produced a do
Autor:
Jean-Marie Stutzmann, Michel Roux, J. Rataud, Jeremy Pratt, Christelle Archambaud, G.Andrees Böhme, Assunta Imperato
Publikováno v:
Neuroscience letters. 272(3)
A cryogenic lesion was produced under halothane anaesthesia in the mouse by placing a cotton swab soaked in liquid nitrogen onto the surface of the cranium. This provoked an oedematous lesion which developed within the hour after the insult and evolv
Publikováno v:
Neuroscience letters. 172(1-2)
This study evaluates the neuroprotective properties of some voltage-sensitive sodium channel blockers in a model of focal ischaemia. After curative treatment (0.5 and 24.5 h after insult), well known voltage-sensitive sodium channel blockers, phenyto
Autor:
A, Doble, T, Canton, S, Dreisler, O, Piot, A, Boireau, J M, Stutzmann, M C, Bardone, J, Rataud, M, Roux, G, Roussel
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 266(3)
This study describes the pharmacological properties of two novel cyclopyrrolone derivatives, RP 59037 [2-(7-chloro-2-naphthyridin-1,8-yl)-3-(5- methyl-2-oxohexyl)isoindolin-1-one] and RP 60503 [2-(7-chloro-2-naphthyridin-1,8-yl)isoindolin-1-yl-4- ace