Zobrazeno 1 - 10
of 29
pro vyhledávání: '"J R Reel"'
Publikováno v:
Biology of reproduction. 65(6)
The present studies were undertaken to determine the testicular cell type(s) affected by the antispermatogenic indenopyridine CDB-4022. At the oral threshold dose (2.5 mg/kg), CDB-4022 induced infertility in all males. CDB-4022 did not alter (P0.05)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ab21c503b9cbabafe18f44c2eb56824
https://pubmed.ncbi.nlm.nih.gov/11717140
https://pubmed.ncbi.nlm.nih.gov/11717140
Publikováno v:
Biology of reproduction. 65(1)
The goals of this study were to determine the CDB-4022 dose-response relationship for induction of acute decreases in testicular weight and germ cell depopulation in rats; establish the threshold dose of CDB-4022 required to induce infertility; and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91f2b66195682351c6b95d143a8488ec
https://pubmed.ncbi.nlm.nih.gov/11420236
https://pubmed.ncbi.nlm.nih.gov/11420236
Publikováno v:
AIDS research and human retroviruses. 14
The objective of this study was to determine whether progestin-only contraceptives induce thinning of the vaginal epithelium in nonhuman primates. Eight intact rhesus monkeys (four per group) were treated with either a single intramuscular injection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8d9fa4dcf30845ec9f8762cfd670b65
https://pubmed.ncbi.nlm.nih.gov/9581896
https://pubmed.ncbi.nlm.nih.gov/9581896
Autor:
D. M. Hollenbaugh, T. A. Barbolt, Richard C. Winneker, P. E. Juniewicz, B. M. Lemp, C. Shaw, J. R. Reel, F. H. Batzold, M. Mccarthy
Publikováno v:
Endocrinology. 126(5)
The effect of the steroidal androgen receptor antagonist Win 49,596 on the prostate and testis was studied in beagle dogs and was compared to the effects of the nonsteroidal androgen receptor antagonist ICI 176,334 and the steroidal 5 alpha-reductase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1997ebcca177656ce4be459e3489f8
https://pubmed.ncbi.nlm.nih.gov/1691701
https://pubmed.ncbi.nlm.nih.gov/1691701
Autor:
M. Mccarthy, T. A. Barbolt, J. R. Reel, F. H. Batzold, P. E. Juniewicz, B. M. Lemp, T. K. Labrie
Publikováno v:
The Prostate. 16(1)
The effects of the steroidal androgen receptor antagonist Win 49,596 on steroid-induced prostatic growth, histomorphology, and secretory function were studied in the castrate male beagle dog. At oral doses ranging from 0.625 to 40 mg/kg/day for 12 we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ec850e146b4e119c38ecd5fd242e9a
https://pubmed.ncbi.nlm.nih.gov/1689481
https://pubmed.ncbi.nlm.nih.gov/1689481
Publikováno v:
Endocrinology. 97:125-135
The distribution of gonadotropinreleasing hormone (GnRH) was studied in the brain of adult female rats with three immunocytochemical techniques using antisera to unconjugated synthetic GnRH and to GnRH conjugated with limpet hemocyanin. GnRH was foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83c5f4d721490726fb9fbd70ac306117
https://doi.org/10.1210/endo-97-1-125
https://doi.org/10.1210/endo-97-1-125
Publikováno v:
Environmental Health Perspectives
Dietary exposure of adult male F344 rats to 0, 320, 1250, 5000, or 20,000 ppm DEHP for 60 consecutive days resulted in a dose-dependent reduction in total body, testis, epididymis, and prostate weights at 5000 and 20,000 ppm. Degenerative changes wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ceba171b549d498a37577e1480e0df5
http://europepmc.org/articles/PMC1474682
http://europepmc.org/articles/PMC1474682
Publikováno v:
The Prostate. 14:341-352
A model for the dose-dependent hormonal induction of benign prostatic hyperplasia (BPH) in castrated dogs has been established using subcutaneously implanted Silastic capsules containing 5 alpha-androstane-3 alpha, 17 beta-diol (3 alpha-diol) and est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b7a092e3ad38b16ff162ab7f614c57
https://doi.org/10.1002/pros.2990140406
https://doi.org/10.1002/pros.2990140406
Publikováno v:
American Journal of Anatomy. 139:129-134
Utilizing immunohistochemistry with rabbit antiserum to synthetic luteinizing hormone-releasing hormone (LRH), LRH was localized in the peripheral region of the median eminence in the mouse and rat, and more generally in the median eminence of the gu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d065fb1d7758ba9821fcf7ade9faf9ed
https://doi.org/10.1002/aja.1001390108
https://doi.org/10.1002/aja.1001390108
Publikováno v:
International journal of fertility. 22(3)
Whereas the administration of LHRH to pregnant hamsters has no effect during the prenidatory period, the hormone is effective in terminating pregnancy when given after implantation (days 6-10). The ED50 for pregnancy termination over this period appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff010d3f8d01254e4634b161432071c0
https://pubmed.ncbi.nlm.nih.gov/24014
https://pubmed.ncbi.nlm.nih.gov/24014