Zobrazeno 1 - 10
of 102
pro vyhledávání: '"J R Lamb"'
Autor:
Marc Feldmann, Christopher E. Rudd, John Trowsdale, J. R. Lamb, Walter F. Bodmer, Penelope Austin
The HLA class II antigens are a highly polymorphic family of dimeric cell-surface glycoproteins, expressed predominantly on the surface of immunocompetent cells. They are intimately involved with the induction of the T-cell response to extrinsic anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d854f4c5956d48ea456f7c9bdceb48
https://doi.org/10.1038/313061a0
https://doi.org/10.1038/313061a0
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 82, Pp 311-323 (1987)
Externí odkaz:
https://doaj.org/article/ce30e5fc928c472e9d2e2b2190ef8c3d
Autor:
J. R. Lamb
Publikováno v:
Research in Immunology. 149:235-240
The exposure of susceptible individuals to environmental allergens induces enhanced levels of specific IgE antibodies, which bind to high affinity receptors on mast cells and basophils. Cross linking of receptor-bound IgE occurs, mediators are releas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74c45bbbfc3a447fc6c1cd6a2116c9a6
https://doi.org/10.1016/s0923-2494(98)80091-6
https://doi.org/10.1016/s0923-2494(98)80091-6
Autor:
Simon Walker, R Dickason, Christopher Corrigan, David P. Huston, Stephen J. Till, A. B. Kay, Stephen R. Durham, Frances O'Brien, J. R. Lamb
Publikováno v:
Clinical and Experimental Immunology. 110:114-121
SUMMARY Grass pollen immunotherapy for the treatment of seasonal allergic rhinitis (‘summer hayfever’) results in improvement in symptoms, a reduction in the early and late phase responses to allergen provocation and decreased tissue eosinophilia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec21db696f9fa672fce6bf209c8becaf
https://doi.org/10.1111/j.1365-2249.1997.494-ce1392.x
https://doi.org/10.1111/j.1365-2249.1997.494-ce1392.x
Publikováno v:
The Journal of Immunology. 157:2160-2165
Changes in the affinity of the interaction between T cell Ag receptors and their ligands can modulate selected T cell effector functions. Since both allergen-specific Th2 and Th0 cells are present in the peripheral CD4+ T cell pool of atopic individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79180a10857d9dbeb523726c72777786
https://doi.org/10.4049/jimmunol.157.5.2160
https://doi.org/10.4049/jimmunol.157.5.2160
Publikováno v:
Clinical Immunology and Immunopathology. 80:S23-S30
Allergic inflammatory responses are regulated by cytokines [interleukin (IL)-4, IL-5, IL-10, and IL-13] produced by CD4+ helper (Th0and Th2) cells. The activation of these T cells follows engagement of T-cell antigen receptors (TCR) by antigenic pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef81023a34520ba7e497a0e6c84df56
https://doi.org/10.1006/clin.1996.0138
https://doi.org/10.1006/clin.1996.0138
Autor:
C. J. M. LORD, J. R. LAMB
Publikováno v:
Clinical Experimental Allergy. 26:756-765
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70cbcd9e8305272eed5e3e09803cde37
https://doi.org/10.1046/j.1365-2222.1996.d01-381.x
https://doi.org/10.1046/j.1365-2222.1996.d01-381.x
Autor:
Gerard F. Hoyne, J. R. Lamb
Publikováno v:
Immunology and Cell Biology. 74:180-186
A major key to successful immunotherapy may depend on altering the qualitative nature of the immune response in allergic patients. In this review we examine how immune responses to environmental allergens are regulated, and the mechanisms used by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056941accd62ae8e87d3fc983c02c114
https://doi.org/10.1038/icb.1996.25
https://doi.org/10.1038/icb.1996.25
Publikováno v:
Clinical & Experimental Allergy. 26:20-27
Summary Background Selected cytokines produced by allergen specific CD4+ T cells from atopic individuals contribute to both the specific and non-specific effector mechanisms of the allergic itnmune response. The chemokine family of cytokines and tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b14bf0003ace1da13ed5af8091fa3d
https://doi.org/10.1111/j.1365-2222.1996.tb00052.x
https://doi.org/10.1111/j.1365-2222.1996.tb00052.x
Publikováno v:
Clinical Experimental Allergy. 25:1163-1170
Summary Background The adhesion molecule LFA-1 contributes to the activation response of peripheral blood human CD4+ T cells. Less is known of its contribution to stimulation of long-term CD4+ T cell lines and clones or of its potential to co-stimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11a33524e34e01f8ba53123d3db5bb5f
https://doi.org/10.1111/j.1365-2222.1995.tb03039.x
https://doi.org/10.1111/j.1365-2222.1995.tb03039.x