Zobrazeno 1 - 7
of 7
pro vyhledávání: '"J R Goodhand"'
Autor:
S Lin, E Hannon, J F Waring, M Reppell, N Smaoui, V L Pivorunas, H Guay, N Chanchlani, C Bewshea, B Y H Bai, N A Kennedy, J R Goodhand, J Mill, T Ahmad
Publikováno v:
Journal of Crohn's and Colitis. 17:i164-i166
Background Anti-TNF treatment failure in patients with IBD is common and frequently related to low drug concentrations. DNA methylation sites from whole blood have been identified as effective biomarkers predicting treatment response to methotrexate
Autor:
S Lin, N A Kennedy, A Saifuddin, D Muñoz Sandoval, C J Reynolds, R C Seoane, S H Kottoor, F P Pieper, K M Lin, D K Butler, N Chanchlani, R Nice, D Chee, C Bewshea, M Janjua, T J McDonald, S Sebastian, J L Alexander, L Constable, J C Lee, C D Murray, A L Hart, P M Irving, G R Jones, K B Kok, C A Lamb, C W Lees, D M Altmann, R J Boyton, J R Goodhand, N Powell, T Ahmad
Publikováno v:
Journal of Crohn's and Colitis. 16:i023-i025
Background Antibody responses following SARS-CoV-2 infection or a single-dose of SARS-CoV-2 vaccine are impaired in patients with inflammatory bowel disease treated with anti-TNF compared to those treated with vedolizumab, a gut-selective anti-integr
Autor:
I Carbery, S Lin, N Chanchlani, M Janjua, R Nice, T J McDonald, C Bewshea, N A Kennedy, T Ahmad, J R Goodhand, C P Selinger
Publikováno v:
Journal of Crohn's and Colitis. 17:i778-i778
Background Lower serum free triiodothyronine-to-thyroxine (fT3/fT4) ratio has been linked to non-response to treatment in a range of diseases, including in biologic-treated patients with IBD. We sought to assess whether baseline serum fT3/fT4 ratio p
Publikováno v:
Alimentary pharmacologytherapeutics. 33(4)
There is increasing concern about the apparently rising incidence and worsening outcome of Clostridium difficile infection (CDI) associated with inflammatory bowel disease (IBD). We have systematically reviewed the literature to evaluate the incidenc
Publikováno v:
Alimentary pharmacologytherapeutics. 33(5)
Although patients with inflammatory bowel disease (IBD) are at increased risk of osteoporosis, low bone mineral density (BMD) alone confers only a modest increase in risk of fracture. The FRAX score, developed by the WHO, is a free web-based clinical
Publikováno v:
Gut. 61:A82.2-A82
Introduction Medical research is focused on the developing of treatments and improving survival outcomes. In recent years, quality of life (QoL) measurements have been included in clinical trials as a relevant outcome variable; however, other psychol
Autor:
P Davies, Christos Toumpanakis, M Mohmaduvesh, J R Goodhand, Jorge Garcia-Hernandez, Martyn Caplin, David Skuse
Publikováno v:
Gut. 61:A252.1-A252
Introduction The relationship between brain serotonin and depression is well established. It is also widely accepted that serotonin hyperproduction in carcinoid syndrome does not cross the brain barrier. CNS serotonin is synthesised from tryptophan w