Zobrazeno 1 - 10
of 12
pro vyhledávání: '"J R Flores-Riveros"'
Publikováno v:
Proceedings of the National Academy of Sciences. 90:3348-3352
Preliminary studies showed that up to 7 kb of 5' flanking sequence of the insulin-responsive glucose transporter (GLUT4) gene are insufficient to mediate differentiation-induced reporter gene expression in mouse 3T3-L1 preadipocytes. To locate the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aafc3342af1c187b7e9a530cb7ffdaf
https://doi.org/10.1073/pnas.90.8.3348
https://doi.org/10.1073/pnas.90.8.3348
Publikováno v:
Proceedings of the National Academy of Sciences. 90:512-516
Insulin rapidly represses expression of the gene encoding the insulin-responsive glucose transporter (GLUT4) in 3T3-L1 mouse adipocytes. Upon exposure to the hormone the cellular level of GLUT4 mRNA falls (t1/2 approximately 2.5 hr) to 20-30% of its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a6a377e0cf1fc307977f2f573a6387
https://doi.org/10.1073/pnas.90.2.512
https://doi.org/10.1073/pnas.90.2.512
Publikováno v:
Journal of Biological Chemistry. 266:9382-9391
Competitive hormone binding studies with membrane and partially purified receptors from Xenopus laevis oocytes revealed that the oocyte possesses high affinity (KD = 1-3 nM) binding sites for both insulin growth factors 1 and 2 (IGF-1 and IGF-2), but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b648511eb984bcfa6dea9ecd3b191c4
https://doi.org/10.1016/s0021-9258(18)92830-9
https://doi.org/10.1016/s0021-9258(18)92830-9
Publikováno v:
Journal of Biological Chemistry. 265:21075-21085
It was established previously that the 15-kDa protein phosphorylated in 3T3-L1 adipocytes treated with insulin and phenylarsine oxide is O-phospho-Tyr19 422(aP2) protein, a fatty acid-binding protein. To assess its capacity to serve as substrate of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14049d99463837cb1d1478375a6218df
https://doi.org/10.1016/s0021-9258(17)45329-4
https://doi.org/10.1016/s0021-9258(17)45329-4
Autor:
R D Hoffman, K H Kaestner, K Liao, R C Hresko, J R Flores-Riveros, T Kastelic, J C McLenithan, Robert J. Christy, M Janicot, M D Lane
Publikováno v:
Diabetes Care. 13:565-575
We identified the earliest events in autophosphorylation of the insulin receptor after insulin addition. Insulinstimulated autophosphorylation at specific sites in the tyrosine kinase domain of the receptor's β-subunit is correlated kinetically with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac95bdb962d8f719e2c8a27e8a2f1850
https://doi.org/10.2337/diacare.13.6.565
https://doi.org/10.2337/diacare.13.6.565
Autor:
Y, Hu, B T, Bloomquist, L J, Cornfield, L B, DeCarr, J R, Flores-Riveros, L, Friedman, P, Jiang, L, Lewis-Higgins, Y, Sadlowski, J, Schaefer, N, Velazquez, M L, McCaleb
Publikováno v:
The Journal of biological chemistry. 271(42)
Neuropeptide Y (NPY) plays important roles in the central control of appetite and energy balance, but the receptor subtype responsible for this function has not been cloned. Here we report the cloning by expression of a novel NPY receptor subtype fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c71a52565332b54ea90b1a09c5666b66
https://pubmed.ncbi.nlm.nih.gov/8824284
https://pubmed.ncbi.nlm.nih.gov/8824284
Publikováno v:
The Journal of biological chemistry. 266(15)
Competitive hormone binding studies with membrane and partially purified receptors from Xenopus laevis oocytes revealed that the oocyte possesses high affinity (KD = 1-3 nM) binding sites for both insulin growth factors 1 and 2 (IGF-1 and IGF-2), but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4a38827aea37caf5f1b37a502f7b942
https://pubmed.ncbi.nlm.nih.gov/1851744
https://pubmed.ncbi.nlm.nih.gov/1851744
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 88(5)
Glucose uptake by adipose tissue is mediated by two glucose transporters: GLUT4, which is most abundant, and GLUT1. While GLUT1 is expressed in many tissues, GLUT4 is unique to tissues that exhibit insulin-stimulated glucose uptake (heart and skeleta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f747a05fa6909a5dc56a9221f6b812a6
https://pubmed.ncbi.nlm.nih.gov/1705711
https://pubmed.ncbi.nlm.nih.gov/1705711
Publikováno v:
The Journal of biological chemistry. 265(34)
It was established previously that the 15-kDa protein phosphorylated in 3T3-L1 adipocytes treated with insulin and phenylarsine oxide is O-phospho-Tyr19 422(aP2) protein, a fatty acid-binding protein. To assess its capacity to serve as substrate of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45d203533f14a34fdb66f0f634f7a547
https://pubmed.ncbi.nlm.nih.gov/2174434
https://pubmed.ncbi.nlm.nih.gov/2174434
Publikováno v:
Journal of Biological Chemistry. 264:21557-21572
The kinetics of insulin-stimulated autophosphorylation of specific tyrosines in the beta subunit of the mouse insulin receptor and activation of receptor kinase-catalyzed phosphorylation of a model substrate were compared. The deduced amino acid sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::097c85cd84758844f9210c628229be1e
https://doi.org/10.1016/s0021-9258(20)88221-0
https://doi.org/10.1016/s0021-9258(20)88221-0