Zobrazeno 1 - 6
of 6
pro vyhledávání: '"J R Fabian"'
Publikováno v:
Molecular and Cellular Biology. 13:7170-7179
The serine/threonine kinase activity of the Raf-1 proto-oncogene product is stimulated by the activation of many tyrosine kinases, including growth factor receptors and pp60v-src. Recent studies of growth factor signal transduction pathways demonstra
Publikováno v:
Molecular and Cellular Biology. 13:7170-7179
The serine/threonine kinase activity of the Raf-1 proto-oncogene product is stimulated by the activation of many tyrosine kinases, including growth factor receptors and pp60v-src. Recent studies of growth factor signal transduction pathways demonstra
Publikováno v:
The Journal of biological chemistry. 273(21)
The guanine nucleotide exchange activity of eIF2B plays a key regulatory role in the translation initiation phase of protein synthesis. The activity is markedly inhibited when the substrate, i. e. eIF2, is phosphorylated on Ser51 of its alpha-subunit
Publikováno v:
Molecular and cellular biology. 15(6)
Recent reports have demonstrated the in vivo association of Raf-1 with members of the 14-3-3 protein family. To address the significance of the Raf-1-14-3-3 interaction, we investigated the enzymatic activity and biological function of Raf-1 in the p
Publikováno v:
Biology of reproduction. 48(6)
The components of the renin-angiotensin system have been detected in various reproductive tissues of mammals including the testis, epididymis, ovary, and placenta. Using Northern blot and in situ hybridization analyses, we detected abundant levels of
Publikováno v:
The Journal of biological chemistry. 264(29)
Inbred strains of mice carry either one of two alleles for the Ren-1 gene on chromosome 1; Ren-1c or Ren-1d. The Ren-1d allele is found in association with a tightly linked duplicated locus, Ren-2. The relative accumulations of renin transcripts deri