Výsledky vyhledávání - "J R E, Del Castillo"

Interindividual variability in plasma concentrations after systemic exposure of swine to dietary doxycycline supplied with and without paracetamol: A population pharmacokinetic approach1

Autor: A. Keïta, Didier Concordet, P. Pommier, Claudine Zemirline, Pierre-Louis Toutain, V. Laroute, J. R. E. del Castillo

Publikováno v: Journal of Animal Science. 84:3155-3166

Anorexigenic substances released during infection may hinder the therapeutic efficacy of in-feed antibiotics. Paracetamol (acetaminophen; PARA) inhibits the anorexia of infection and seems to improve the clinical efficacy of doxycycline (DOX) against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50dfbb7e872dc5ee6b31a0d7b5b392cc
https://doi.org/10.2527/jas.2005-561

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The use of the noninferiority analysis in clinical studies

Autor: E C, Bermingham, J R E, del Castillo, S V, Radecki

Publikováno v: Equine veterinary journal. 46(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ca6527b7dee60bf1b37c09739b21cc8b
https://pubmed.ncbi.nlm.nih.gov/24909652

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Comparison of continuous infusion with intermittent bolus administration of cefotaxime on blood and cavity fluid drug concentrations in neonatal foals

Autor: J, Hewson, R, Johnson, L G, Arroyo, A, Diaz-Mendez, J A, Ruiz-López, Y, Gu, J R E, del Castillo

Publikováno v: Journal of veterinary pharmacology and therapeutics. 36(1)

Healthy neonatal foals were treated with cefotaxime by bolus (40 mg/kg i.v. q6h for 12 doses; n=10) or by infusion (loading dose of 40 mg/kg i.v. followed by continuous infusion of a total daily dose of 160 mg/kg per 24 h for 3 days; n=5). Population

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49f4dfd38be00be159c38c1020de779e
https://pubmed.ncbi.nlm.nih.gov/22489635

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Demonstrating bioequivalence using clinical endpoint studies

Autor: E, Bermingham, J R E, Del Castillo, C, Lainesse, K, Pasloske, S, Radecki

Publikováno v: Journal of veterinary pharmacology and therapeutics. 35

For drug products not amenable to blood level studies, clinical endpoint studies have been used as an indirect measure of formulation difference in bioavailability between test and reference products. However, clinical endpoint studies are not as sen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9f6d56510bd3815a5447fc31f104193f
https://pubmed.ncbi.nlm.nih.gov/22413789

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Interindividual variability in plasma concentrations after systemic exposure of swine to dietary doxycycline supplied with and without paracetamol: a population pharmacokinetic approach

Autor: J R E, del Castillo, V, Laroute, P, Pommier, C, Zémirline, A, Keïta, D, Concordet, P-L, Toutain

Publikováno v: Journal of animal science. 84(11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::33946489c4ae3e4adb79428f89d23940
https://pubmed.ncbi.nlm.nih.gov/17032811

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