Zobrazeno 1 - 10
of 12
pro vyhledávání: '"J R Adair"'
Autor:
V L Pulito, V A Roberts, J R Adair, A L Rothermel, A M Collins, S S Varga, C Martocello, M Bodmer, L K Jolliffe, R A Zivin
Publikováno v:
The Journal of Immunology. 156:2840-2850
OKT4A, a murine mAb that recognizes an epitope on the CD4 receptor, is a potent immunosuppressive agent in vitro and in a variety of nonhuman primate models of graft rejection and autoimmune disease. Initial human cardiac transplant trials suggest th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf77649c606ea2b414be381a76794a5d
https://doi.org/10.4049/jimmunol.156.8.2840
https://doi.org/10.4049/jimmunol.156.8.2840
Autor:
D J, King, J R, Adair
Publikováno v:
Current opinion in drug discoverydevelopment. 2(2)
It is nearly 25 years since the first description of monoclonal antibodies. During that time, monoclonal antibodies and derivatives have become a major group of pharmaceuticals in development. Technical problems have, however, hindered their developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a9a9f8eb12b9f5f8eea5df1fdecd329
https://pubmed.ncbi.nlm.nih.gov/19649936
https://pubmed.ncbi.nlm.nih.gov/19649936
Autor:
J. L. Shenep, J. R. Adair, W. T. Hughes, P. K. Roberson, P. M. Flynn, T. O. Brodkey, G. H. Fullen, W. T. Kennedy, L. L. Oakes, N. M. Marina
Publikováno v:
Clinical Pediatrics. 30:36-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5219185119e1c8da7bae06a67c3d5091
https://doi.org/10.1177/000992289103000411
https://doi.org/10.1177/000992289103000411
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::067e8eeb1100382a469a574f40041a4e
https://pubmed.ncbi.nlm.nih.gov/9664399
https://pubmed.ncbi.nlm.nih.gov/9664399
Autor:
V L, Pulito, V A, Roberts, J R, Adair, A L, Rothermel, A M, Collins, S S, Varga, C, Martocello, M, Bodmer, L K, Jolliffe, R A, Zivin
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(8)
OKT4A, a murine mAb that recognizes an epitope on the CD4 receptor, is a potent immunosuppressive agent in vitro and in a variety of nonhuman primate models of graft rejection and autoimmune disease. Initial human cardiac transplant trials suggest th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bea1cddbebff22ca3395c90c192cfb19
https://pubmed.ncbi.nlm.nih.gov/8609403
https://pubmed.ncbi.nlm.nih.gov/8609403
Autor:
D J, King, A, Turner, A P, Farnsworth, J R, Adair, R J, Owens, R B, Pedley, D, Baldock, K A, Proudfoot, A D, Lawson, N R, Beeley
Publikováno v:
Cancer research. 54(23)
The construction and use of recombinant chimeric and later fully humanized (CDR-grafted) antibodies to tumor-associated antigens has reduced the immune response generated to these antibodies in clinical studies. However, their long circulating half-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c076df48ab54533ce1f88c269cee177
https://pubmed.ncbi.nlm.nih.gov/7954464
https://pubmed.ncbi.nlm.nih.gov/7954464
Autor:
J R, Adair, D S, Athwal, M W, Bodmer, S M, Bright, A M, Collins, V L, Pulito, P E, Rao, R, Reedman, A L, Rothermel, D, Xu
Publikováno v:
Human antibodies and hybridomas. 5(1-2)
OKT3 is a murine monoclonal antibody which recognizes an epitope on the epsilon-subunit within the human CD3 complex. OKT3 possesses potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3feab3d72c19934158251d7b78b6f5a
https://pubmed.ncbi.nlm.nih.gov/7858182
https://pubmed.ncbi.nlm.nih.gov/7858182
Autor:
E S, Woodle, J R, Thistlethwaite, L K, Jolliffe, R A, Zivin, A, Collins, J R, Adair, M, Bodmer, D, Athwal, M L, Alegre, J A, Bluestone
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 148(9)
Antibodies that possess the Ag-binding regions of OKT3 within the context of a human framework (Hu-OKT3 Ab) offer distinct advantages for optimizing anti-CD3 mAb therapy. First, manipulation of Ab genes to produce humanized Ab that retain Ag-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd2b9542f5c4d4cf2a7a4399b5a66674
https://pubmed.ncbi.nlm.nih.gov/1533410
https://pubmed.ncbi.nlm.nih.gov/1533410
Autor:
Philip M. Williams, N. R. A. Beeley, J. R. Adair, S. J. B. Tendler, David E. Jackson, Clive J. Roberts, K. M. Kreusel, M. C. Davies
Publikováno v:
Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures. 12:1517
Images have been obtained of two types of chimeric B72.3 anti‐TAG‐72 mutant hinge IgG4 antibodies using scanning tunneling microscopy. The antibodies were specifically engineered to show differences in their conformation due to site specific modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0262726cdad6e2443c2c2641b43005ee
https://doi.org/10.1116/1.587276
https://doi.org/10.1116/1.587276
Autor:
J R, Adair, D E, Theobald
Publikováno v:
The Journal of the Indiana State Medical Association. 71(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de2329e088e4153fc136a84e156fda7a
https://pubmed.ncbi.nlm.nih.gov/701835
https://pubmed.ncbi.nlm.nih.gov/701835