Zobrazeno 1 - 10
of 333
pro vyhledávání: '"J R Adair"'
Publikováno v:
Vetus Testamentum, 2003 Oct 01. 53(4), 562-562.
Externí odkaz:
https://www.jstor.org/stable/1518563
Publikováno v:
The Military Engineer, 1969 Jul 01. 61(402), 316-316.
Externí odkaz:
https://www.jstor.org/stable/44565515
Autor:
V L Pulito, V A Roberts, J R Adair, A L Rothermel, A M Collins, S S Varga, C Martocello, M Bodmer, L K Jolliffe, R A Zivin
Publikováno v:
The Journal of Immunology. 156:2840-2850
OKT4A, a murine mAb that recognizes an epitope on the CD4 receptor, is a potent immunosuppressive agent in vitro and in a variety of nonhuman primate models of graft rejection and autoimmune disease. Initial human cardiac transplant trials suggest th
Autor:
D J, King, J R, Adair
Publikováno v:
Current opinion in drug discoverydevelopment. 2(2)
It is nearly 25 years since the first description of monoclonal antibodies. During that time, monoclonal antibodies and derivatives have become a major group of pharmaceuticals in development. Technical problems have, however, hindered their developm
Autor:
J. L. Shenep, J. R. Adair, W. T. Hughes, P. K. Roberson, P. M. Flynn, T. O. Brodkey, G. H. Fullen, W. T. Kennedy, L. L. Oakes, N. M. Marina
Publikováno v:
Clinical Pediatrics. 30:36-41
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 80
Autor:
D J, King, A, Turner, A P, Farnsworth, J R, Adair, R J, Owens, R B, Pedley, D, Baldock, K A, Proudfoot, A D, Lawson, N R, Beeley
Publikováno v:
Cancer research. 54(23)
The construction and use of recombinant chimeric and later fully humanized (CDR-grafted) antibodies to tumor-associated antigens has reduced the immune response generated to these antibodies in clinical studies. However, their long circulating half-l
Autor:
J R, Adair, D S, Athwal, M W, Bodmer, S M, Bright, A M, Collins, V L, Pulito, P E, Rao, R, Reedman, A L, Rothermel, D, Xu
Publikováno v:
Human antibodies and hybridomas. 5(1-2)
OKT3 is a murine monoclonal antibody which recognizes an epitope on the epsilon-subunit within the human CD3 complex. OKT3 possesses potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver
Autor:
E S, Woodle, J R, Thistlethwaite, L K, Jolliffe, R A, Zivin, A, Collins, J R, Adair, M, Bodmer, D, Athwal, M L, Alegre, J A, Bluestone
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 148(9)
Antibodies that possess the Ag-binding regions of OKT3 within the context of a human framework (Hu-OKT3 Ab) offer distinct advantages for optimizing anti-CD3 mAb therapy. First, manipulation of Ab genes to produce humanized Ab that retain Ag-binding
Autor:
Philip M. Williams, N. R. A. Beeley, J. R. Adair, S. J. B. Tendler, David E. Jackson, Clive J. Roberts, K. M. Kreusel, M. C. Davies
Publikováno v:
Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures. 12:1517
Images have been obtained of two types of chimeric B72.3 anti‐TAG‐72 mutant hinge IgG4 antibodies using scanning tunneling microscopy. The antibodies were specifically engineered to show differences in their conformation due to site specific modi