Zobrazeno 1 - 10 of 33 pro vyhledávání: '"J R, Zucali"'
1
Prevention of graft-versus-host disease by induction of immune tolerance with ultraviolet B-irradiated leukocytes in H-2 disparate bone marrow donor
Autor: M L, del Rosario, J R, Zucali, K J, Kao
Publikováno v: Blood. 93(10)
Transfusions (Tx) of Ultraviolet B (UVB)-irradiated peripheral blood mononuclear leukocytes (MNL) have been shown to induce humoral immune tolerance to major histocompatability complex (MHC) antigens (Blood 88:4375, 1996). To determine whether cellul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a7089412ba42c39b82cd034d63b50d4f
https://pubmed.ncbi.nlm.nih.gov/10233909
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2
Overexpression of the human aldehyde dehydrogenase class I results in increased resistance to 4-hydroperoxycyclophosphamide
Autor: J, Moreb, M, Schweder, A, Suresh, J R, Zucali
Publikováno v: Cancer gene therapy. 3(1)
A correlation between overexpression of aldehyde dehydrogenase and resistance to oxazaphosphorines, widely used anticancer agents, has been shown. To investigate the direct role of the human aldehyde dehydrogenase class 1 (ALDH-1) in the resistance t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c7d3115bdca89a13a9d3171fc1b12533
https://pubmed.ncbi.nlm.nih.gov/8785707
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3
Role of manganese superoxide dismutase in radioprotection using gene transfer studies
Autor: A, Suresh, F, Tung, J, Moreb, J R, Zucali
Publikováno v: Cancer gene therapy. 1(2)
Overexpression of manganese superoxide dismutase (MnSOD) has been postulated as one possible mechanism of radioprotection for hematopoietic cells. In this study retroviral constructs having the human MnSOD gene in both the sense and antisense orienta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::43b95ed2b772afbb9cf20c7b0a2ff5aa
https://pubmed.ncbi.nlm.nih.gov/7621245
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4
Radioprotection of hematopoietic stem cells by interleukin-1
Autor: J R, Zucali, J, Moreb, W, Gibbons, J, Alderman, A, Suresh, Y, Zhang, B, Shelby
Publikováno v: Experimental hematology. 22(2)
Radioprotective agents such as interleukin-1 (IL-1) and tumor necrosis factor (TNF-alpha), when given prior to irradiation, protect animals from radiation damage. However, in vivo administration of these cytokines does not allow one to determine whet
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91872735c48d9372d1741c75b4f16c1c
https://pubmed.ncbi.nlm.nih.gov/8299734
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6
A role for manganese superoxide dismutase in radioprotection of hematopoietic stem cells by interleukin-1
Autor: J, Eastgate, J, Moreb, H S, Nick, K, Suzuki, N, Taniguchi, J R, Zucali
Publikováno v: Blood. 81(3)
Pretreatment with interleukin-1 (IL-1) has been shown to protect mice from the myelotoxicity associated with irradiation via a mechanism potentially mediated through the induction of the antioxidant enzyme manganese superoxide dismutase (MnSOD). In t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::644c476cb08f26cdb96c03ec863b8c10
https://pubmed.ncbi.nlm.nih.gov/8427959
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7
Protection of cells capable of reconstituting long-term bone marrow stromal cultures from 4-hydroperoxycyclophosphamide by interleukin 1 and tumor necrosis factor
Autor: J R, Zucali, J, Moreb, C, Bain
Publikováno v: Experimental hematology. 20(8)
The cytokines interleukin 1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) have been implicated in protecting normal hematopoiesis from both irradiation and chemotherapy damage. The mechanism of action of these cytokines and which cells are prote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::182c5b51195b0941fa789d77b0f5b1b2
https://pubmed.ncbi.nlm.nih.gov/1505642
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8
Role of aldehyde dehydrogenase in the protection of hematopoietic progenitor cells from 4-hydroperoxycyclophosphamide by interleukin 1 beta and tumor necrosis factor
Autor: J, Moreb, J R, Zucali, Y, Zhang, M O, Colvin, M A, Gross
Publikováno v: Cancer research. 52(7)
Preincubation of human bone marrow cells with interleukin 1 beta (IL-1) and tumor necrosis factor alpha (TNF-alpha) for 20 h can protect early progenitor cells from 4-hydroperoxycyclophosphamide (4-HC) toxicity. In this report, we have studied the me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8647b2e3118975a815573e07f7c3e964
https://pubmed.ncbi.nlm.nih.gov/1551107
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9
Effects in vivo of purified recombinant human activin and erythropoietin in mice
Autor: H E, Broxmeyer, G, Hangoc, J R, Zucali, A, Mason, R, Schwall, C, Carow, S, Cooper
Publikováno v: International journal of hematology. 54(6)
Activin has been shown to act in vitro as an erythroid specific enhancing activity for erythropoietin (epo)-stimulated erythroid (BFU-E) and multipotential (CFU-GEMM) progenitor cells. To evaluate effects in vivo, purified recombinant activin-A and e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76acaeb7a90cffb63d5e1f10156e2e78
https://pubmed.ncbi.nlm.nih.gov/1793828
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10
Human N-terminal analogs of interleukin 1 beta demonstrate altered binding and function in hematopoiesis
Autor: J R, Zucali, J, Moreb, R C, Newton, J J, Huaog
Publikováno v: Experimental hematology. 18(10)
This study describes the structure-function relationship of interleukin 1 beta (IL-1 beta) using two amino-terminal muteins of human IL-1 beta. One mutein, clone 18, which substitutes a threonine and methionine for the alanine and proline at position
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d38816f20b6d920d50d1dd6f2c4b8d45
https://pubmed.ncbi.nlm.nih.gov/2145179
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