Zobrazeno 1 - 10 of 32 pro vyhledávání: '"J R, Trudell"'
2
Molecular modeling of ligand-gated ion channels: progress and challenges
Autor: E, Bertaccini, J R, Trudell
Publikováno v: International review of neurobiology. 48
There has been rapid progress in molecular modeling of LGICs in recent years. The convergence of improved software for molecular mechanics/dynamics, techniques of chimeric substitution and site-directed mutations, and the first X-ray structures of tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c77e68faa801f51817f79e900d71b381
https://pubmed.ncbi.nlm.nih.gov/11526737
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3
Time course of 72-kilodalton heat shock protein induction and appearance of trifluoroacetyl adducts in livers of halothane-exposed rats
Autor: W Q, Lin, R A, van Dyke, H M, Marsh, J R, Trudell
Publikováno v: Molecular pharmacology. 46(4)
Previous studies have shown that exposure of phenobarbital-pretreated rats to halothane in 10% O2 causes centrilobular necrosis, induces expression of the 72-kDa heat shock protein (HSP72), and produces several trifluoroacetylated adducts. In the pre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::10d14184b6347c7ed2728940865a57fc
https://pubmed.ncbi.nlm.nih.gov/7526150
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4
Antibodies raised against trifluoroacetyl-protein adducts bind to N-trifluoroacetyl-phosphatidylethanolamine in hexagonal phase phospholipid micelles
Autor: J R, Trudell, C M, Ardies, W R, Anderson
Publikováno v: The Journal of pharmacology and experimental therapeutics. 257(2)
The delayed fulminant form of halothane hepatotoxicity is thought to be triggered by an immune response to haptenic adducts formed by a metabolite, trifluoroacetyl chloride. In this study we demonstrate that antibodies purified from the sera of rabbi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2f099fd9bb0c31f5001bffa29a27eed
https://pubmed.ncbi.nlm.nih.gov/2033512
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6
Cross-reactivity of antibodies raised against acetaldehyde adducts of protein with acetaldehyde adducts of phosphatidyl-ethanolamine: possible role in alcoholic cirrhosis
Autor: J R, Trudell, C M, Ardies, W R, Anderson
Publikováno v: Molecular pharmacology. 38(5)
This study measured the possible cross-reactivity of hapten-specific IgG antibodies purified from the sera of rabbits sensitized to an albumin-acetaldehyde conjugate [N-ethyl-rabbit serum albumin (N-ethyl-RSA)] with acetaldehyde-phosphatidylethanolam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a862c9fa07ddad6b399c61c665464680
https://pubmed.ncbi.nlm.nih.gov/2233695
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7
Phospholipid transfer between vesicles. Dependence on presence of cytochrome P-450 and phosphatidylcholine-phosphatidylethanolamine ratio
Autor: B, Bösterling, J R, Trudell
Publikováno v: Biochimica et biophysica acta. 689(1)
The rate of transfer of spin-labeled phospholipid from donor vesicles of sonicated 1-acyl-2-(10-doxylstearoyl)-sn-glycero-3-phosphocholine to other vesicle was determined as a function of content of cytochrome P-450 and the phosphatidylcholine/phosph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2cde257e69af9d615eabc12d78be94a6
https://pubmed.ncbi.nlm.nih.gov/6285973
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