Zobrazeno 1 - 10
of 17
pro vyhledávání: '"J R, Reddan"'
Publikováno v:
Investigative ophthalmologyvisual science. 37(10)
Cell lines are the systems of choice to analyze cellular functions related to the particular organ system. For lens research, three cell lines are widely used: N/N1003A (derived from rabbit lenses), alpha TN4, and NKR-11 (both of murine origin). The
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 42(2)
Oxidative stress is thought to play a major role in cataract formation. The present experiments are aimed at gaining a better understanding of the systems that protect the lens from damage by reactive oxygen species. The aqueous humor normally contai
Publikováno v:
Investigative ophthalmologyvisual science. 37(1)
To study the functional significance of prostaglandin synthesis after ultraviolet-B (UVB) exposure of cultured human lens epithelial cells and rabbit eyes in vivo.Prostaglandin E2 (PGE2) was assayed using a radioimmunoassay (RIA) and mass spectroscop
Publikováno v:
Cytobios. 85(340)
The effect of hydrogen peroxide on cultured neonatal and adult cardiac myocytes was investigated. On neonatal cardiac myocytes the effect was very pronounced at a low concentration (0.03 mM), whereas the adult cardiac myocytes were resistant to the s
Publikováno v:
Investigative ophthalmologyvisual science. 36(2)
To investigate the effect of hydrogen peroxide on the epithelial cells of cultured rabbit lenses.Lenses were cultured in minimum essential medium containing a single dose of 0.03, 0.1, or 0.2 mM H2O2. Three hours later the medium was replaced with pe
Publikováno v:
Investigative ophthalmologyvisual science. 36(2)
To determine if lens epithelial lines can be established from cryopreserved whole rabbit lenses and from cryopreserved capsule-epithelial preparations (CEPs).Lenses or freshly isolated CEPs were cryopreserved and subsequently thawed. Thawed whole len
Publikováno v:
Investigative ophthalmologyvisual science. 35(2)
This study was done to quantitate the biologic effects of different wavelengths of radiation in the UVA- and UVB-wavelength region on cultured rabbit lens epithelial cells.An action spectrum for UV-induced cytotoxicity as measured by colony-forming a
Publikováno v:
Investigative ophthalmologyvisual science. 35(2)
The goals of this investigation were to examine the synthesis of prostaglandins after UVB exposure of lens epithelial cells and to investigate their role in cell proliferation.Cultured rabbit lens epithelial cells (cell line N/N1003A) were exposed to
Autor:
J R, Reddan, D, Wilson-Dziedzic
Publikováno v:
Investigative ophthalmologyvisual science. 24(4)
The mitogenicity of insulin, insulin growth factor (IGF), and epidermal growth factor (EGF) was evaluated on rabbit lenses cultured in medium KEI-4. IGF, the most highly purified of the insulin-like growth factors was a potent mitogen for mammalian l
Publikováno v:
Current eye research. 2(8)
Lenses were cultured in Medium 199 containing 14C acetate for 3, 6, 12 and 20 hours. There was a linear increase in incorporation into the total lipids with time. The total lipid extract was subjected to two-dimensional chromatography and incorporati