Zobrazeno 1 - 10
of 13
pro vyhledávání: '"J R, Pfeiffer"'
Autor:
Frederick M. Howard, Gong He, Joseph R. Peterson, J. R. Pfeiffer, Tyler Earnest, Alexander T. Pearson, Hiroyuki Abe, John A. Cole, Rita Nanda
Publikováno v:
Breast cancer research and treatment. 196(1)
Purpose Pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) in early breast cancer (EBC) is largely dependent on breast cancer subtype, but no clinical-grade model exists to predict response and guide selection of treatment. A biophy
Autor:
Rebecca J. Lee, Y Platt, N Kapp, Janet M. Oliver, A M Martinez, F Letourneur, Bridget S. Wilson, J R Pfeiffer
Publikováno v:
Journal of Biological Chemistry. 270:4013-4022
In RBL-2H3 rat tumor mast cells, cross-linking the high affinity IgE receptor, Fc epsilon R1, activates the protein-tyrosine kinases Lyn and Syk and initiates a series of responses including protein-tyrosine phosphorylation, inositol 1,4,5-trisphosph
Publikováno v:
The Journal of Immunology. 151:2760-2774
IgE receptors of mast cells, Fc epsilon RI, localize to coated pits and internalize after cross-linking. We investigated whether any one of the receptor's four distinctive cytoplasmic domains regulates these phenomena. COS cells, which lack Fc epsilo
Publikováno v:
The Journal of Immunology. 146:3528-3535
In the 2H3 subline of rat basophilic leukemia cells (RBL-2H3), IgE receptor cross-linking stimulates a signal transduction pathway that leads to the secretion of histamine, serotonin, and other inflammatory mediators; the assembly of F-actin; and the
Autor:
E, Ortega, M, Lara, I, Lee, C, Santana, A M, Martinez, J R, Pfeiffer, R J, Lee, B S, Wilson, J M, Oliver
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(1)
Cross-linking the heterotrimeric (alpha beta gamma 2) IgE receptor, Fc epsilon RI, of mast cells activates two tyrosine kinases: Lyn, which phosphorylates beta and gamma subunit immunoreceptor tyrosine-based activation motifs, and Syk, which binds ga
Autor:
T E, Graham, J R, Pfeiffer, R J, Lee, D F, Kusewitt, A M, Martinez, T, Foutz, B S, Wilson, J M, Oliver
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(12)
Cross-linking the high affinity IgE receptor Fc epsilonRI of basophils and mast cells activates receptor-associated protein-tyrosine kinases and stimulates a signaling cascade leading to secretion, ruffling, spreading, and cytokine production. Previo
Autor:
B S, Wilson, N, Kapp, R J, Lee, J R, Pfeiffer, A M, Martinez, Y, Platt, F, Letourneur, J M, Oliver
Publikováno v:
The Journal of biological chemistry. 270(8)
In RBL-2H3 rat tumor mast cells, cross-linking the high affinity IgE receptor, Fc epsilon R1, activates the protein-tyrosine kinases Lyn and Syk and initiates a series of responses including protein-tyrosine phosphorylation, inositol 1,4,5-trisphosph
Autor:
J R, Pfeiffer, J M, Oliver
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(1)
RBL-2H3 rat tumor mast cells form monolayers on various surfaces without assembling specialized adhesion structures at the cell substrate interface. Incubation of RBL-2H3 cells with Ag that cross-link the high affinity IgE receptor, Fc epsilon R1, ac
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(5)
IgE receptors of mast cells, Fc epsilon RI, localize to coated pits and internalize after cross-linking. We investigated whether any one of the receptor's four distinctive cytoplasmic domains regulates these phenomena. COS cells, which lack Fc epsilo
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 146(10)
In the 2H3 subline of rat basophilic leukemia cells (RBL-2H3), IgE receptor cross-linking stimulates a signal transduction pathway that leads to the secretion of histamine, serotonin, and other inflammatory mediators; the assembly of F-actin; and the