Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J R, Okita"'
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 46:93-98
The specific activity of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (PGDH) was found to increase in the ovaries of pregnant and pseudopregnant rabbits. The mean specific activity of cytosolic ovarian PGDH in 14- to 28-day pregnant rabbits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbed25708813c1e59c716cdab3213aa7
https://doi.org/10.1016/0952-3278(92)90214-4
https://doi.org/10.1016/0952-3278(92)90214-4
Autor:
R C, Zangar, J R, Okita, H, Kim, P E, Thomas, A, Anderson, R J, Edwards, D L, Springer, R T, Okita
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(3)
Calcium channel antagonists are widely prescribed for treatment of hypertension. In this study, we examined whether treatment with the calcium channel antagonists, nicardipine, nifedipine or diltiazem, alters cytochrome P-450 2B or 3A (CYP2B or CYP3A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46d2483f63881e57d3819a3a038fc6a5
https://pubmed.ncbi.nlm.nih.gov/10454523
https://pubmed.ncbi.nlm.nih.gov/10454523
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(8)
In the study of tissues that contain several forms of one cytochrome P450 subfamily, it is useful to develop immunoblotting techniques so that the various individual members of the family can be distinguished. This paper describes improvements in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e216409c648867190f913c5c32af56ba
https://pubmed.ncbi.nlm.nih.gov/9280410
https://pubmed.ncbi.nlm.nih.gov/9280410
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(2)
Lauramide diethanolamine (LDEA)--a compound used in cosmetics and soap products as an emollient, thickener, and foam stabilizer--was observed to be metabolized by rat liver microsomes to two major products that were identified by GC/MS to be the 11-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33011d0b205d5654245daa40574772fb
https://pubmed.ncbi.nlm.nih.gov/8742229
https://pubmed.ncbi.nlm.nih.gov/8742229
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(10)
Nine male and five female human liver microsomal sample were examined for laurate 11- and 12-hydroxylase activities. The mean specific activities for the 11- and 12-hydroxylation reactions were 0.78 +/- 0.33 and 1.07 +/- 0.12 nmol/min/mg protein, res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d699b48b4b1c775d7fc2bfde6652b4e
https://pubmed.ncbi.nlm.nih.gov/8654190
https://pubmed.ncbi.nlm.nih.gov/8654190
Effects of diethyl phthalate and other plasticizers on laurate hydroxylation in rat liver microsomes
Autor:
R T, Okita, J R, Okita
Publikováno v:
Pharmaceutical research. 9(12)
Diethyl phthalate (DEP) is used in pharmaceutical coatings, cosmetics, and plastic films to wrap foods. There is a health concern associated with the exposure to certain phthalate esters because they belong to a class of compounds referred to as pero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9fe50cb69dc667cd7dc6e19af38c84a
https://pubmed.ncbi.nlm.nih.gov/1488412
https://pubmed.ncbi.nlm.nih.gov/1488412
Publikováno v:
Methods in enzymology. 206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8454df0d7e6503525b4d11b5156d80e
https://pubmed.ncbi.nlm.nih.gov/1784228
https://pubmed.ncbi.nlm.nih.gov/1784228
Publikováno v:
Blood. 74:715-721
Platelets from patients with Montreal platelet syndrome (MPS) consistently display a defect in the mechanisms that regulate platelet size during shape change and undergo spontaneous aggregation and stir- induced microaggregate formation. We now provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee714de28bba5cb81c0938010a3be53d
https://doi.org/10.1182/blood.v74.2.715.bloodjournal742715
https://doi.org/10.1182/blood.v74.2.715.bloodjournal742715
Publikováno v:
Journal of Biological Chemistry. 257:14029-14034
Arachidonic acid is mobilized from the fetal membranes (amnion and chorion laeve) during human parturition. To define the lipid species that serve as the source of arachidonic acid, we determined the lipid composition of fetal membranes obtained befo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09ef1e4cce4a5332d35d658f4a164fbb
https://doi.org/10.1016/s0021-9258(19)45338-6
https://doi.org/10.1016/s0021-9258(19)45338-6
Publikováno v:
The Journal of Cell Biology
Glycoprotein (GP) Ib was purified from lysates of human platelets prepared in the presence or absence of inhibitors of the endogenous calcium-activated neutral protease (CANP) by immunoaffinity chromatography, employing the GPIb-specific murine monoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43034ab0a339c87cc7a15e5987e25777
http://europepmc.org/articles/PMC2113466
http://europepmc.org/articles/PMC2113466