Zobrazeno 1 - 10 of 30 pro vyhledávání: '"J R, Nevins"'
1
Molecular Analyses of Two Poly(A) Site-Processing Factors That Determine the Recognition and Efficiency of Cleavage of the Pre-mRNA
Autor: G M, Gilmartin, J R, Nevins
Publikováno v: Molecular and Cellular Biology. 11:2432-2438
Poly(A) site processing of a pre-mRNA requires the participation of multiple nuclear factors. Two of these factors recognize specific sequences in the pre-mRNA and form a stable processing complex. Since these initial interactions are likely critical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc59061edc0a60da6511826b3d62e753
https://doi.org/10.1128/mcb.11.5.2432-2438.1991
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2
Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
Autor: W C, Lin, F T, Lin, J R, Nevins
Publikováno v: Genesdevelopment. 15(14)
Previous work has established a role for p53 in triggering apoptosis in response to DNA damage; p53 also induces apoptosis in response to deregulation of the Rb cell cycle pathway. The latter event is consistent with a role for the Rb-regulated E2F1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6bd00d60c9548523ba817db394cc0cdb
https://pubmed.ncbi.nlm.nih.gov/11459832
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4
Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth
Autor: E J, Smith, G, Leone, J R, Nevins
Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 9(4)
A variety of studies have demonstrated the critical role of the Rb/E2F pathway in the control of cell growth and have highlighted a complexity in the accumulation of both the E2F family proteins and the Rb family of proteins. Whereas the Rb protein i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ea80c488f5cc2b7a2bb952e61fcd46f
https://pubmed.ncbi.nlm.nih.gov/9563849
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6
Use of the E2F Transcription Factor by DNA Tumor Virus Regulatory Proteins
Autor: J. R. Nevins, W. D. Cress
Publikováno v: Current Topics in Microbiology and Immunology ISBN: 9783642799129
In most cases the normal host cell for infection by the DNA tumor virus is a quiescent, terminally differentiated cell that is not dividing. Various experiments have demonstrated that upon infection these cells are stimulated to enter S phase, as ind
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21b797aced1575b2de7362f0387dd312
https://doi.org/10.1007/978-3-642-79910-5_3
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8
Identification of distinct roles for separate E1A domains in disruption of E2F complexes
Autor: M A, Ikeda, J R, Nevins
Publikováno v: Molecular and cellular biology. 13(11)
The adenovirus E1A protein can disrupt protein complexes containing the E2F transcription factor in association with cellular regulatory proteins such as the retinoblastoma gene product (Rb) and the Rb-related p107 protein. Previous experiments have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf35eedf1a53eb680b530dda0de90219
https://pubmed.ncbi.nlm.nih.gov/8413292
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9
E4F and ATF, two transcription factors that recognize the same site, can be distinguished both physically and functionally: a role for E4F in E1A trans activation
Autor: R J, Rooney, P, Raychaudhuri, J R, Nevins
Publikováno v: Molecular and cellular biology. 10(10)
Previous experiments have identified an element in the adenovirus E4 promoter that is critical for E1A-dependent trans activation and that can confer inducibility to a heterologous promoter. This DNA element is a recognition site for multiple nuclear
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::68b698578efca48df46f1b10324ae6e8
https://pubmed.ncbi.nlm.nih.gov/2169022
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10
Adenovirus E1A-dependent trans-activation of transcription
Autor: J R, Nevins
Publikováno v: Seminars in cancer biology. 1(1)
The study of E1A-mediated trans-activation of adenovirus transcription has provided insight into mechanisms controlling transcription factor activity. Almost certainly, multiple cellular transcription factors contribute to the trans-activation proces
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::db435129d75b64cd9cc3aeeaa317e22e
https://pubmed.ncbi.nlm.nih.gov/2133112
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