Zobrazeno 1 - 10
of 38
pro vyhledávání: '"J R, Mead"'
Publikováno v:
Nucleic Acids Research
Increasing evidence suggests that the cytokine transforming growth factor-beta (TGF-beta) inhibits the development of atherosclerosis. The lipoprotein lipase (LPL) enzyme expressed by macrophages has been implicated in the pathogenesis of atheroscler
Publikováno v:
Journal of Biological Chemistry. 278:17741-17751
Interferon-γ (IFN-γ) is a pleiotropic cytokine that modulates the immune function, cell proliferation, apoptosis, macrophage activation, and numerous other cellular responses. These biological actions of IFN-γ are characterized by both the activat
Autor:
Dipak Purshottam Ramji, J. R. Mead
Publikováno v:
Cardiovascular Research. 55:261-269
Time for primary review 33 days. Atherosclerosis, the underlying cause of heart attacks, stroke and peripheral vascular disease, is responsible for over 50% of all deaths in developed countries. The disease can generally be viewed as a form of chroni
Publikováno v:
Parasite immunology. 34(10)
Cryptosporidium parvum is an opportunistic intracellular parasite that causes mild to severe diarrhoea, which can be life-threatening in an immunocompromised host. To increase our understanding of the mechanisms that play a role in host immune respon
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:1837-1842
Severe combined immunodeficient (SCID) mice were found to be highly susceptible to murine cytomegalovirus (MCMV) infection. Treatment of infected mice with ganciclovir (12.5, 25, and 50 mg/kg of body weight for 10 days) starting 24 h after virus chal
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 80(12)
Lipoprotein lipase (LPL) catalyses the hydrolysis of the triacylglycerol component of circulating chylomicrons and very low density lipoproteins, thereby providing non-esterified fatty acids and 2-monoacylglycerol for tissue utilisation. Research car
Publikováno v:
The Journal of eukaryotic microbiology. 46(5)
Autor:
J. R. Mead, Xiangdong You
Publikováno v:
Parasitology. 117
Severe cryptosporidial infections were produced in gamma interferon (IFN-γ) knockout mice. Mean oocyst shedding increased from 332 to 30717 oocysts/100 μl of faecal suspension between day 4 and 9 after administration of 1×105 oocysts/mouse. No sig
Publikováno v:
The Journal of parasitology. 84(5)
Differences in susceptibility to cryptosporidial infections were investigated between 2 strains of gamma interferon knockout (GKO) mice. Male C57BL/6J-Ifg and BALB/c-Ifg (GKO) mice, ages 8-10 wk, were inoculated with infectious oocysts at various dos
Publikováno v:
The Journal of parasitology. 81(3)
A flow cytometric method for the quantification of Cryptosporidium parvum oocysts in stool specimens was developed to replace conventional microscopic immunofluorescent assays. Fecal pellets were collected from control (uninfected) severe combined im