Zobrazeno 1 - 10
of 13
pro vyhledávání: '"J R, Luderer"'
Publikováno v:
European Journal of Clinical Pharmacology. 45:437-443
We have studied the pharmacokinetics and haemodynamic effects of nicorandil after a 12-h infusion. Nicorandil is a mixed vasodilator combining the actions of a nitrate and a potassium channel opener. Nicorandil was infused for 12 h in 21 healthy volu
Publikováno v:
European Journal of Clinical Pharmacology. 44:27-33
We have studied the effects of intravenous nicorandil, a mixed arterial and venous vasodilator, in 48 healthy volunteers. Nicorandil (20, 28, 39, 54, 74, 103, 144, or 200 μg·kg−1) or placebo were given over 5 min to subjects supine (16 subjects,
Publikováno v:
International journal of clinical pharmacology and therapeutics. 32(5)
The effects of nicorandil, a nicotinamide derived vasodilator combining nitrate and potassium channel opener actions, on kidney function have not been determined. This study investigated changes in renal blood flow and glomerular filtration rate as e
Autor:
H A, Harvey, J C, Allegra, L M, Demers, J R, Luderer, D E, Brenner, J J, Trautlein, D S, White, M A, Gillin, A, Lipton
Publikováno v:
Cancer. 39(6)
Prostaglandins, unsaturated fatty acid derivatives with diversified pharmacologic activity, have been implicated in the pathophysiology of many diseases. Prostaglandin E (PGE) levels were measured by radioimmunoassay in the plasma of 41 normocalcemic
Publikováno v:
Advances in prostaglandin and thromboxane research. 8
Publikováno v:
Transactions - American Society for Artificial Internal Organs. 28
Publikováno v:
Archives of pathologylaboratory medicine. 101(7)
The histopathologic characteristics of a patient with progressive myopathy, renal failure, hemoptysis, and a fulminant terminal event demonstrated a diffuse vasculitis, type 2 fiber atrophy of muscle, and linear IgG staining of the basement membranes
Publikováno v:
The Journal of family practice. 16(5)
Fifty-nine nursing home patients (average age, 79.9 +/- .9 years) receiving chlorpropamide were screened with a serum sodium determination. Nine patients (15.3 percent) had a serum sodium concentration less than 135 mEq/L; six of these patients (10.2
Autor:
J R, Luderer
Publikováno v:
Clinical therapeutics. 5(2)
Publikováno v:
Research communications in chemical pathology and pharmacology. 28(1)
The effects of hydralazine on arachidonic acid metabolism were studied in isolated washed human platelets. The washed platelets (10(9)/ml) were exposed to 14C-arachidonic acid and incubated for 15 minutes in a platelet aggregometer (37 degrees C). Th