Zobrazeno 1 - 10
of 27
pro vyhledávání: '"J R, Kuszak"'
Autor:
Ren-Rong Wang, Guangyi Wang, Wanchao Ma, M Weiss, A M Cotliar, A Spector, Wan-Cheng Li, J R Kuszak, M Leib, Kenneth W. Dunn
Publikováno v:
The Journal of Cell Biology
Cataract is a major ocular disease that causes blindness in many developing countries of the world. It is well established that various factors such as oxidative stress, UV, and other toxic agents can induce both in vivo and in vitro cataract formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9275199ef0e5a91836a9202cae2fb92
https://doi.org/10.1083/jcb.130.1.169
https://doi.org/10.1083/jcb.130.1.169
Publikováno v:
Experimental Eye Research. 59:521-535
We have quantified the influence of lens sutural anatomy on optical quality (focal length variability, i.e. spherical aberration) in adult monkeys (Macaque nemestrina). Adult lenses (n = 6) were initially scanned by a low-power helium-neon laser beam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a470717b1352e3301402ad65cc035c16
https://doi.org/10.1006/exer.1994.1138
https://doi.org/10.1006/exer.1994.1138
Autor:
J R, Kuszak, J G, Sivak, K L, Moran, S A, Scheib, W H, Garner, T L, Ke, M R, Hellberg, G, Graff
Publikováno v:
Experimental eye research. 75(4)
This study reports for the first time a therapeutic modality for the suppression of posterior subcapsular cataract (PSC) formation in an animal model (rabbit) of vitrectomy. This therapeutic modality may also have the potential to attenuate/prevent t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cbf371c04b0483b90d902a1de997c2c3
https://pubmed.ncbi.nlm.nih.gov/12387793
https://pubmed.ncbi.nlm.nih.gov/12387793
Autor:
M B, Kelz, J R, Kuszak, Y, Yang, W, Ma, C, Steffen, K, Al-Ghoul, Y J, Zhang, J, Chen, E J, Nestler, A, Spector
Publikováno v:
Investigative ophthalmologyvisual science. 41(11)
The objective of this study was to investigate a possible relationship between posterior subcapsular cataract (PSC) formation and expression of the transcription factor DeltaFosB.Western blot analysis was performed on bitransgenic NSE-tTA, TetOp-Delt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::042e6cc6539443b2e02924e949c63fe8
https://pubmed.ncbi.nlm.nih.gov/11006248
https://pubmed.ncbi.nlm.nih.gov/11006248
Publikováno v:
Investigative ophthalmologyvisual science. 41(11)
To examine the effects of refractive error on avian lens morphology and optical quality.Hatchling white leghorn chicks were unilaterally goggled for 7 days with either a form-deprivation goggle (n = 12), a -10 D defocus goggle (n = 12), or a +10 D de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1de326f246d6c48c31e9b28562fc37a9
https://pubmed.ncbi.nlm.nih.gov/11006247
https://pubmed.ncbi.nlm.nih.gov/11006247
Publikováno v:
Investigative ophthalmologyvisual science. 41(2)
To obtain in vivo specular images of human lens epithelial cells (LECs) from persons with or without age-related cataract (ARC); to identify features that describe individual aspects of these complex images; to develop feature scales to quantify the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbdc67695c6e6f5ce6a198be3620b551
https://pubmed.ncbi.nlm.nih.gov/10670478
https://pubmed.ncbi.nlm.nih.gov/10670478
Publikováno v:
Investigative ophthalmologyvisual science. 40(8)
Intracellular osmotic stress is believed to be linked to the advancement of diabetic cataract. Although the accumulation of organic osmolytes (myo-inositol, sorbitol, taurine) is thought to protect the lens by maintaining osmotic homeostasis, the phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4352a5355988f29f88d6b96ed76ec997
https://pubmed.ncbi.nlm.nih.gov/10393042
https://pubmed.ncbi.nlm.nih.gov/10393042
Publikováno v:
Molecular vision. 5
To document lens ultrastructure during and after internalization of posterior subcapsular cataracts (PSCs) in Royal College of Surgeons (RCS) rats, a model for human autosomal retinal degenerative disease.RCS rat lenses at 2, 2.5, 3, 4, 6, 9, 12, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29dba23b7f4fb13594a5d7f3a3bc1906
https://pubmed.ncbi.nlm.nih.gov/10329769
https://pubmed.ncbi.nlm.nih.gov/10329769
Publikováno v:
Molecular vision. 5
The Royal College of Surgeons (RCS) rat is an animal model for human retinal degenerative disease and posterior subcapsular cataracts (PSCs). The purpose of this study was to correlate the structure and optical quality of RCS lenses with PSCs as a fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c34a962ed4d59b2da88544114e7872d
https://pubmed.ncbi.nlm.nih.gov/10329770
https://pubmed.ncbi.nlm.nih.gov/10329770
Autor:
K J, Al-Ghoul, J R, Kuszak
Publikováno v:
Investigative ophthalmologyvisual science. 40(3)
The objective of this study was to characterize the morphology of the anterior opacities formed during recovery from posterior subcapsular cataract (PSC) in Royal College of Surgeons (RCS) rats.Lenses from RCS rats at 8 and 12 weeks postnatal (n = 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af0fc5ac66c6bc9041a383b217714add
https://pubmed.ncbi.nlm.nih.gov/10067970
https://pubmed.ncbi.nlm.nih.gov/10067970